Gene Information

Name : Cgl2089 (NCgl2008)
Accession : NP_601288.2
Strain : Corynebacterium glutamicum ATCC 13032
Genome accession: NC_003450
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2205665 - 2207092 bp
Length : 1428 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
GTGGATAGACGAACTAAGATTGTATGTACCCTAGGCCCAGCGGTGGCTAGTGCAGATGGAATTCTGCGTTTGGTAGAAGA
CGGCATGGATGTTGCTCGCCTCAACTTCTCCCATGGTGACCACCCAGATCATGAGCAAAACTACAAGTGGGTCCGCGAGG
CGGCGGAGAAGACTGGCCGTGCAGTCGGTATTCTCGCAGACCTCCAAGGACCGAAGATCCGTCTTGGCCGTTTCACTGAC
GGCGCAACCGTGTGGGAAAACGGCGAGACCATTCGGATCACCGTTGACGATGTAGAGGGAACGCACGATCGTGTGTCCAC
CACCTACAAGAATCTGGCAAAAGACGCGAAGCCAGGCGACCGCCTGCTCGTTGATGACGGCAAGGTTGGCCTCGTCTGCG
TTTCCGTCGAAGGTAACGACGTCATCTGTGAGGTTGTTGAGGGCGGACCAGTCTCCAACAACAAGGGTGTTTCCCTGCCA
GGTATGGATATTTCCGTACCTGCACTGTCCGAAAAGGATATCCGTGACCTGCGCTTCGCCCTGAAGCTCGGCGTGGACTT
TATTGCACTGTCCTTCGTACGTTCCCCAGCAGATGCTGAACTCGTTCACAAGATCATGGACGAAGAAGGTCGTCGTGTTC
CTGTGATCGCCAAGCTGGAAAAGCCAGAGGCTGTCACCTCCCTCGAGCCAATCGTGTTGGCATTCGACGCCGTCATGGTT
GCTCGTGGTGACCTCGGCGTTGAGGTTCCTCTGGAGGAGGTTCCACTGGTTCAGAAGCGCGCAATCCAGATTGCCCGTGA
GAACGCAAAGCCAGTTATCGTGGCAACCCAGATGCTGGATTCCATGATTGAGAACTCCCGCCCAACCCGTGCGGAAGCTT
CTGACGTGGCAAACGCTGTGCTCGATGGCGCAGATGCTGTCATGCTTTCTGGTGAAACTTCAGTGGGCAAAGATCCGCAC
AACGTTGTGCGCACCATGTCTCGCATTGTTCGCTTCGCTGAAACCGACGGTCGCGTCCCAGACCTGACCCACATCCCTCG
CACTAAGCGTGGCGTTATTTCCTACTCTGCACGTGATATCGCCGAGCGCCTCAACGCTCGTGCATTGGTTGCGTTCACCA
CCTCTGGTGATACCGCAAAGCGTGTGGCTCGTCTGCACAGCCACCTGCCACTGCTCGTGTTCACTCCAAATGAGGCAGTT
CGCTCTGAGCTGGCGCTGACCTGGGGTGCAACCACCTTCCTGTGTCCACCTGTCAGCGATACCGATGACATGATGCGCGA
AGTCGACCGTGCTCTTTTAGCAATGCCTGAGTACAACAAGGGTGACATGATGGTTGTTGTTGCAGGTTCCCCTCCTGGTG
TTACCGGTAACACCAACATGATTCACGTCCACCTTCTTGGTGACGACACAAGGATTGCAAAGCTCTAA

Protein sequence :
MDRRTKIVCTLGPAVASADGILRLVEDGMDVARLNFSHGDHPDHEQNYKWVREAAEKTGRAVGILADLQGPKIRLGRFTD
GATVWENGETIRITVDDVEGTHDRVSTTYKNLAKDAKPGDRLLVDDGKVGLVCVSVEGNDVICEVVEGGPVSNNKGVSLP
GMDISVPALSEKDIRDLRFALKLGVDFIALSFVRSPADAELVHKIMDEEGRRVPVIAKLEKPEAVTSLEPIVLAFDAVMV
ARGDLGVEVPLEEVPLVQKRAIQIARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKDPH
NVVRTMSRIVRFAETDGRVPDLTHIPRTKRGVISYSARDIAERLNARALVAFTTSGDTAKRVARLHSHLPLLVFTPNEAV
RSELALTWGATTFLCPPVSDTDDMMREVDRALLAMPEYNKGDMMVVVAGSPPGVTGNTNMIHVHLLGDDTRIAKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-69 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-69 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 6e-69 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cgl2089 NP_601288.2 pyruvate kinase VFG0479 Protein 3e-69 42