Gene Information

Name : Cgl1305 (NCgl1253)
Accession : NP_600527.1
Strain : Corynebacterium glutamicum ATCC 13032
Genome accession: NC_003450
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 1369874 - 1371637 bp
Length : 1764 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGACGCCTACCCAAAATGAGATCCACCCGAAACATAGCTACTCCCCCATCCGCAAGGACGGTCTCGAGGTCCCGGAGAC
CGAAATCCGCCTCGATGACTCGCCAAGCGGCCCCAACGAACCCTTCCGCATCTACCGCACCCGTGGCCCAGAAACCAACC
CCAAGCAGGGACTTCCGCGGCTGCGCGAGTCATGGATCACCGCCCGCGGCGACGTTGCCACCTATCAGGGGCGCGAGCGT
TTGCTTATCGACGACGGCCGCTCGGCAATGCGTCGAGGTCAAGCTTCGGCTGAGTGGAAAGGCCAAAAACCAGCTCCTTT
GAAGGCGCTACCTGGCAAAAGAGTCACCCAAATGGCCTATGCACGTGCTGGCGTGATTACTCGTGAAATGGAGTTTGTAG
CGCTGCGCGAACACGTTGATGCGGAGTTTGTGCGCTCTGAGGTGGCGCGCGGTCGGGCCATTATTCCCAACAACGTCAAC
CACCCCGAATCTGAACCGATGATTATTGGTCGCAAATTTTTGACCAAAATCAACGCCAATATTGGCAATTCTGCGGTCAC
CTCTTCAATCGAGGAAGAGGTGTCCAAGCTGCAGTGGGCCACGCGCTGGGGTGCCGATACCGTGATGGATCTATCCACCG
GCGATGATATTCACACCACCCGCGAATGGATTATCCGCAACTCCCCCGTTCCTATCGGCACCGTCCCGATCTACCAAGCG
CTGGAAAAAGTAAATGGCGTGGCCGCAGACCTTAACTGGGAAGTATTCCGCGATACCATCATTGAGCAGTGTGAACAAGG
CGTGGACTATATGACCATCCACGCCGGCGTCCTGCTGGCTTATATCCCACTGACTACCCGTCGTGTCACCGGCATTGTCT
CCCGCGGCGGATCCATTATGGCCGGTTGGTGTCTGGCGCATCACCGCGAATCATTCCTCTACGAGCATTTCGACGAGCTG
TGCGAAATCTTTGCACAATATGACGTCGCATTCTCCCTCGGTGATGGCCTACGCCCCGGATCGCTTGCCGATGCCAACGA
CGCCGCGCAATTCGCCGAGCTGAAAACCATTGGTGAGCTCACCCAACGCGCCTGGGAATACGATGTACAAGTAATGGTCG
AAGGACCTGGACACGTGCCACTAAACATGATCCAGGAAAACAACGAGCTGGAACAAAAGTGGGCAGCGGACGCACCTTTT
TACACTCTTGGACCACTAGTTACCGACATCGCTCCAGGTTATGACCACATCACTTCTGCCATTGGTGCAGCTCACATCGC
CATGGGTGGCACCGCCATGCTGTGTTATGTCACCCCGAAAGAACACCTTGGCCTGCCCAACCGTGACGACGTCAAAACCG
GCGTAATCACCTACAAGCTCGCTGCCCACGCAGCAGATGTGGCCAAGGGTCATCCCGGCGCGCGTGCCTGGGACGACGCC
ATGAGTAAAGCGCGTTTTGAATTCCGTTGGAATGATCAGTTTGCGCTCTCCCTCGACCCCGACACTGCAATCGCTTATCA
CGACGAAACCCTGCCGGCAGAGCCTGCGAAAACCGCACACTTCTGTTCAATGTGTGGCCCGAAGTTCTGCTCCATGCGAA
TTAGCCAGGACATTCGCGATATGTTTGGCGATCAAATCGCGGAATTGGGGATGCCTGGGGTTGGGGATTCTTCTAGTGCT
GTTGCTTCTAGTGGGGCACGGGAGGGGATGGCTGAGAAATCCCGGGAATTTATTGCTGGTGGTGCGGAGGTTTATCGGCG
TTAG

Protein sequence :
MTPTQNEIHPKHSYSPIRKDGLEVPETEIRLDDSPSGPNEPFRIYRTRGPETNPKQGLPRLRESWITARGDVATYQGRER
LLIDDGRSAMRRGQASAEWKGQKPAPLKALPGKRVTQMAYARAGVITREMEFVALREHVDAEFVRSEVARGRAIIPNNVN
HPESEPMIIGRKFLTKINANIGNSAVTSSIEEEVSKLQWATRWGADTVMDLSTGDDIHTTREWIIRNSPVPIGTVPIYQA
LEKVNGVAADLNWEVFRDTIIEQCEQGVDYMTIHAGVLLAYIPLTTRRVTGIVSRGGSIMAGWCLAHHRESFLYEHFDEL
CEIFAQYDVAFSLGDGLRPGSLADANDAAQFAELKTIGELTQRAWEYDVQVMVEGPGHVPLNMIQENNELEQKWAADAPF
YTLGPLVTDIAPGYDHITSAIGAAHIAMGGTAMLCYVTPKEHLGLPNRDDVKTGVITYKLAAHAADVAKGHPGARAWDDA
MSKARFEFRWNDQFALSLDPDTAIAYHDETLPAEPAKTAHFCSMCGPKFCSMRISQDIRDMFGDQIAELGMPGVGDSSSA
VASSGAREGMAEKSREFIAGGAEVYRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 1e-171 63
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 1e-171 63
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 6e-163 58