Gene Information

Name : tpx (NCgl1041)
Accession : NP_600314.1
Strain : Corynebacterium glutamicum ATCC 13032
Genome accession: NC_003450
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : 1.11.1.-
Position : 1134552 - 1135058 bp
Length : 507 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGGGGTCCATGGCTAAAACACATTTTCAAGGCAACGAAACTGCTACCTCCGGCGAACTGCCACAGGTCGGCGACAACCT
CGCAGAGTTCAACCTCGTCAACACCGAACTGGGCGAGGTCTCCTCAAAGGACTTCCAGGGCCGCAAGCTTGTCCTGAACA
TCTTCCCATCCGTTGACACCGGCGTTTGTGCAACATCAGTCCGCAAGTTCAACGAGGCAGCAGCAAGCCTGGAAAACACC
ACCGTGCTGTGCATCTCCAAGGATCTTCCATTCGCACTGGGCCGTTTCTGCTCCGCAGAAGGCATCGAGAACGTCACCCC
AGTATCCGCATTCCGTTCCACCTTCGGTGAAGACAACGGCATCGTGCTCGAAGGCTCACCACTTAAGGGTCTTCTTGCAC
GCAGCGTCATCGTCGTCGATGAAAACGGCAAGGTTGCTTACACCCAGTTGGTTGATGAGATCTCCACTGAACCTGATTAC
GACGCTGCACTTGCTGCGCTGAACTAA

Protein sequence : 
MGSMAKTHFQGNETATSGELPQVGDNLAEFNLVNTELGEVSSKDFQGRKLVLNIFPSVDTGVCATSVRKFNEAAASLENT
TVLCISKDLPFALGRFCSAEGIENVTPVSAFRSTFGEDNGIVLEGSPLKGLLARSVIVVDENGKVAYTQLVDEISTEPDY
DAALAALN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 5e-36 47
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 3e-36 47
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 9e-36 46
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 6e-36 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx NP_600314.1 thiol peroxidase VFG0087 Protein 1e-36 47