Gene Information

Name : PF1188 (PF1188)
Accession : NP_578917.1
Strain : Pyrococcus furiosus DSM 3638
Genome accession: NC_003413
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1134061 - 1135494 bp
Length : 1434 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
GTGAGAAGGGTGAAGCTCCCATCTCACAAGACAAAAATTGTAGCTACAATAGGGCCAGCGACTAATTCGAGAAAAATGAT
AAAACAACTCATTAAGGCGGGGATGAATGTTGCAAGAATAAACTTCTCCCATGGAAGTTTTGAAGAGCATGCAAGAGTCA
TAGAAATAATAAGAGAGGAGGCACAAAAATTAGACAGGAGAGTTGCAATACTTGCAGATCTACCTGGATTGAAAATAAGA
GTCGGTGAGATAAAAGGGGGTTACGTAGAGCTAAAGAGAGGAGAAAAGGTAATATTAACAACAAAGGATGTTGAGGGTGA
TGAAACTACGATACCAGTGGATTATAAAGGCTTTCCAAATTTGGTATCGAAGGGAGACATCATATACCTTAATGACGGAT
ACATAGTCTTAAAGGTGGAGAACGTTAGGGAGAACGAAGTTGAAGCAGTTGTTCTTTCAGGAGGAAAGCTCTTCTCGAGA
AAGGGCGTCAATATACCCAAGGCCTACCTCCCAGTCGAAGCCATAACTCCAAAAGACTTTGAAATTATGAAATTTGCAAT
TGAGCATGGGGTGGATGCAATAGGATTGAGCTTCGTTGGGAGCGTTTATGATGTTCTAAAGGCCAAGAGTTTCCTTGAGA
AAAATAATGCCGAGGATGTATTTGTAATTGCAAAGATCGAAAGACCTGACGCCGTGAGGAATTTTGACGAGATTCTTAAT
GCCGCTGATGGAATTATGATTGCTAGAGGAGATTTAGGGGTAGAGATGCCGATAGAGCAGCTACCAATTCTTCAGAAGAA
ATTGATCAGGAAAGCCAATATGGAAGGGAAACCAGTGATTACGGCAACACAAATGCTTGTGTCAATGACAACGGAAAAAG
TGCCAACAAGGGCCGAAGTTACGGACGTTGCAAACGCAATTCTTGATGGAACGGATGCAGTTATGCTATCAGAAGAAACG
GCCATAGGAAAATTCCCCATTGAGACCGTAGAGATGATGGGAAAGATAGCTAAGGTCACTGAAGAATATAGGGAAAGTTT
TGGGTTAAGCAGAATAAGGGAGTTTATGGAGATCAAAAAGGGAACAATAAAAGAGGCTATCACTAGAAGTATAATTGACG
CAATATGCACAATAGACATTAAGTTTATACTAACACCCACCAGAACGGGAAGAACTGCTAGGCTAATCTCAAGATTTAAG
CCCAAGCAGTGGATTTTAGCCTTCTCAACAAATGAAAGGGTGTGCAACAATCTCATGTTCAGCTATGGAGTTTATCCCTT
CTGCCTAGAAGAGGGATTCGATGAGAACGATATAGTTAGGTTGATAAAAGGACTGGGCCTTGTGGAAAGCGATGATATGG
TTTTAATGACGGAAGGAAAGCCAATTGAAAAAACAGTTGGAACTAACTCAATTAAGATATTCCAAATAGCTTGA

Protein sequence :
MRRVKLPSHKTKIVATIGPATNSRKMIKQLIKAGMNVARINFSHGSFEEHARVIEIIREEAQKLDRRVAILADLPGLKIR
VGEIKGGYVELKRGEKVILTTKDVEGDETTIPVDYKGFPNLVSKGDIIYLNDGYIVLKVENVRENEVEAVVLSGGKLFSR
KGVNIPKAYLPVEAITPKDFEIMKFAIEHGVDAIGLSFVGSVYDVLKAKSFLEKNNAEDVFVIAKIERPDAVRNFDEILN
AADGIMIARGDLGVEMPIEQLPILQKKLIRKANMEGKPVITATQMLVSMTTEKVPTRAEVTDVANAILDGTDAVMLSEET
AIGKFPIETVEMMGKIAKVTEEYRESFGLSRIREFMEIKKGTIKEAITRSIIDAICTIDIKFILTPTRTGRTARLISRFK
PKQWILAFSTNERVCNNLMFSYGVYPFCLEEGFDENDIVRLIKGLGLVESDDMVLMTEGKPIEKTVGTNSIKIFQIA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-63 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 5e-64 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 5e-64 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PF1188 NP_578917.1 pyruvate kinase VFG0479 Protein 2e-64 41