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Name : dhfR (HCM1.165c) Accession : NP_569370.1 Strain : Genome accession: NC_003384 Putative virulence/resistance : Resistance Product : dihydrofolate reductase Function : - COG functional category : H : Coenzyme transport and metabolism COG ID : COG0262 EC number : 1.5.1.3 Position : 120417 - 120899 bp Length : 483 bp Strand : - Note : similar to (EMBL:X12868) dhfRV from Escherichia coli DNA sequence : ATGAGAACCTTGAAAGTATCATTGATGGCTGCGAAAGCGAAAAACGGCGTGATTGGTTGCGGTCCAGACATACCCTGGTC CGCGAAAGGGGAGCAGCTACTTTTTAAAGCATTGACCTACAATCAGTGGCTTCTGGTGGGTCGCAAGACGTTTGAATCTA TGGGCGCACTCCCCAATAGGAAATACGCGGTCGTTACCCGCTCAGGTTGGACATCAAATGATGACAATGTAGTTGTATTT CAGTCAATCGAAGAGGCCATGGACAGGCTAGCTGAATTCACCGGTCACGTTATAGTGTCTGGTGGCGGAGAAATTTACCG AGAAACATTACCCATGGCCTCTACGCTCCACTTATCGACGATCGACATCGAGCCAGAGGGGGATGTTTTCTTCCCGAGTA TTCCAAATACCTTCGAAGTTGTTTTTGAGCAACACTTTACTTCAAACATTAACTATTGCTATCAAATTTGGAAAAAGGGT TAA Protein sequence : MRTLKVSLMAAKAKNGVIGCGPDIPWSAKGEQLLFKALTYNQWLLVGRKTFESMGALPNRKYAVVTRSGWTSNDDNVVVF QSIEEAMDRLAEFTGHVIVSGGGEIYRETLPMASTLHLSTIDIEPEGDVFFPSIPNTFEVVFEQHFTSNINYCYQIWKKG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| dfrA5 | AFG30110.1 | dihydrofolate reductase | Not tested | PAGI-2 | Protein | 6e-63 | 91 |
| dfrA5 | AET25387.1 | dihydrofolate reductase | Not tested | PAGI-2(C) | Protein | 6e-63 | 91 |
| dfrA1 | ADZ05803.1 | trimethoprim-insensitive dihydrofolate reductase | Not tested | AbaR3 | Protein | 4e-65 | 90 |
| unnamed | AEL12695.1 | DfrA5 | Not tested | AbaR21 | Protein | 4e-65 | 90 |
| dfrA15 | AGK07099.1 | DfrA15 dihydrofolate reductase | Not tested | SGI1 | Protein | 6e-55 | 75 |
| dfrA1 | AAX48777.1 | DfrA1 trimethoprim-insensitive dihydrofolate reductase | Not tested | SGI2 | Protein | 1e-53 | 72 |
| dfrI | CAJ77029.1 | dihydrofolate reductase type I | Not tested | AbaR1 | Protein | 1e-53 | 72 |
| dfrA1 | AGF34987.1 | DfrA1 dihydrofolate reductase | Not tested | SGI1 | Protein | 1e-53 | 72 |
