Gene Information

Name : merD (HCM1.159)
Accession : NP_569365.1
Strain :
Genome accession: NC_003384
Putative virulence/resistance : Resistance
Product : transcriptional regulator MerD
Function : -
COG functional category : K : Transcription
COG ID : COG0789
EC number : -
Position : 117909 - 118274 bp
Length : 366 bp
Strand : +
Note : similar to (EMBL:Z00027) merD from Pseudomonas aeruginosa plasmid pVS1; similar to HCM1.230

DNA sequence :
ATGAGCGCCTACACAGTGTCCCGGCTGGCCCTTGATGCCGGGGTGAGCGTGCATATCGTGCGCGACTACCTGCTGCGCGG
ATTGCTACGGCCGGTCGCGTACACCACGGGCGGCTACGGCTTGTTCGATGACACCGCGTTGCAACGGCTGCGCTTTGTAC
GGGCTGCCTTCGAAGCGGGTATCGGCCTGGACGCACTGGCGCGGCTGTGCCGGGCGCTGGATGCTGCGGACGGTGACGGT
GCGTCTGCGCAGCTTGCCGTGTTGCGGCAACTCGTCGAGCGTCGGCGCGAGGCCCTGGCCAGCCTCGAAATGCAACTGGC
CGCCATGCCAACCGAACCGGCACAGCACGCGGAGAGTCTGCCATGA

Protein sequence :
MSAYTVSRLALDAGVSVHIVRDYLLRGLLRPVAYTTGGYGLFDDTALQRLRFVRAAFEAGIGLDALARLCRALDAADGDG
ASAQLAVLRQLVERRREALASLEMQLAAMPTEPAQHAESLP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merD ACN81004.1 MerD Not tested AbaR5 Protein 2e-36 100
merD CAJ77059.1 Mercury operon coregulator protein Not tested AbaR1 Protein 1e-36 100
merD AGK07020.1 MerD Not tested SGI1 Protein 8e-32 90
merD AGK07078.1 MerD Not tested SGI1 Protein 8e-32 90
merD ABQ57370.1 MerD Not tested SGI1 Protein 2e-31 89
merD YP_006098386.1 MerR family transcriptional regulator Not tested Tn2411 Protein 1e-27 83
merD ACF06181.1 mercuric resistance protein Not tested Tn5036-like Protein 7e-28 83
merD AET25396.1 MerD Not tested PAGI-2(C) Protein 7e-28 83
merD AFG30119.1 MerD Not tested PAGI-2 Protein 7e-28 83

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merD NP_569365.1 transcriptional regulator MerD BAC0666 Protein 3e-32 91
merD NP_569365.1 transcriptional regulator MerD BAC0668 Protein 3e-32 90
merD NP_569365.1 transcriptional regulator MerD BAC0665 Protein 4e-33 90
merD NP_569365.1 transcriptional regulator MerD BAC0667 Protein 3e-34 89
merD NP_569365.1 transcriptional regulator MerD BAC0227 Protein 7e-32 89
merD NP_569365.1 transcriptional regulator MerD BAC0669 Protein 2e-33 84