Gene Information

Name : fhuC (CPE0813)
Accession : NP_561729.1
Strain : Clostridium perfringens 13
Genome accession: NC_003366
Putative virulence/resistance : Virulence
Product : ferrichrome ABC transporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 997182 - 997964 bp
Length : 783 bp
Strand : +
Note : similar to sp:FHUC_BACSU FERRICHROME TRANSPORT ATP-BINDING PROTEIN FHUC from Bacillus subtilis (269 aa); 55.4% identity in 260 aa overlap; ATP-binding protein

DNA sequence :
ATGAATTGTATAACTACTGATAATTTAAATATTTCATATGGAAGTTTAGATATAGTTAAAAATTTAAACTTAAAGATACC
AAAGGGGAAAATAACTACAATAATAGGTGCAAATGGATGTGGAAAATCTACAGTGCTAAAAACAATAGCTAGAATTTTAA
CTCCTAAAAGTGGGGAAATATATATAAATGAAAAAAACATAAAAGAGCAGGGAGCTAAGGAGTTAGCAAAGGTTATGGCA
GTTTTACCTCAAAGTCCTCAAGCACCTAATGGGCTTACTGTTGAAGAGTTAATAGCCTATGGAAGATTCCCTCATCAAAA
AGGATTCGGTAAATTAAAAAAAGAGGACAAAAATATAATTCAATGGGCTTTAGAGGTTACAGGATTAATTGAATTTAGGG
AAAGAGACATAGAAGATTTATCTGGAGGGCAAAGACAAAGAGCTTGGATTGCTATGGCCTTAGCACAGCAAACAGATATA
TTAATACTTGATGAGCCAACAACTTATTTAGATTTAGCCCATCAATTAGAGATTTTAAATTTACTTAAGGAATTGAATGA
GAAGCATGGGACAACTATAGTTATGGTTATTCATGAACTTAATAATGCTGCTAGATTTGCCGATTATATGATAGGTATGA
AAGCAGGAAAAATAGCTTGCCAAGGTACAGCATACGAAGTTATGACAAAAGAAAATCTTAAAGGGCTGTTTAATATAGAT
GCAGAAATTATAGAGGATCCAAGAAATAAAAGACCAGTCTGTGTGACTTATGATATGTTATAA

Protein sequence :
MNCITTDNLNISYGSLDIVKNLNLKIPKGKITTIIGANGCGKSTVLKTIARILTPKSGEIYINEKNIKEQGAKELAKVMA
VLPQSPQAPNGLTVEELIAYGRFPHQKGFGKLKKEDKNIIQWALEVTGLIEFRERDIEDLSGGQRQRAWIAMALAQQTDI
LILDEPTTYLDLAHQLEILNLLKELNEKHGTTIVMVIHELNNAARFADYMIGMKAGKIACQGTAYEVMTKENLKGLFNID
AEIIEDPRNKRPVCVTYDML

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 8e-45 46
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 8e-45 46
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 8e-40 45
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 8e-40 45
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 7e-40 45
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 7e-40 45
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 1e-43 43
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 2e-43 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fhuC NP_561729.1 ferrichrome ABC transporter BAC0164 Protein 8e-44 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fhuC NP_561729.1 ferrichrome ABC transporter VFG1042 Protein 8e-44 43
fhuC NP_561729.1 ferrichrome ABC transporter VFG0925 Protein 7e-44 43