Gene Information

Name : apbA (CPE0786)
Accession : NP_561702.1
Strain : Clostridium perfringens 13
Genome accession: NC_003366
Putative virulence/resistance : Unknown
Product : 2-dehydropantoate 2-reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1893
EC number : 1.1.1.169
Position : 970747 - 971673 bp
Length : 927 bp
Strand : +
Note : ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis

DNA sequence :
ATGAAAATCGCAATTGTTGGAGCAGGAGCAATGGGCTCACGTTATGGATATATGTTACATGAAGCTGGAAATGAAGTTAT
GCTAATAGATGGGTGGAAGGATCATGTAGATACTATAAACAAAGAGGGATTAACTGTTGAGGAAAATGGAGAAATTAAAA
AAGTAAAGATACCAGCAATGCTACCTCAAGATGCTAAAGAAATTCCAGAGTTAATAATATTATTTACTAAATCTATGGGA
TTAGAATCAATGTTAGAATCTATAAAAGGTATATTAGGAAAAAATACAAAGGTATTATGCCTATTAAATGGATTAGGACA
TAATGAAACTGTAGCAAAATATGTTGATAGCAAAAACATACTTATGGGAGTAACTTTATGGACAGCTGGGTTAAAAGGTC
CAGGACATGTTGTATTAACAGGAAGCGGAAGCCTAGAAGTTCAAAATATTGATCCAAGTATGGAAAAAGAGGCAAAAGAA
ATTTGTGATATATTAAGTAATGCTGGATTAAAAGCTCACTATAGTGAAAATGTATTATTTTCAATATGGCGTAAAGCTTG
CGTAAATGGAACTTTAAATAGTGGATGTACAATTTTAGATTGTAATATTAAAGAATTTGGTGAATTAAAAGAAGCTCCAG
AGCTTATACGTAATATCATAAAAGAATTTGCTGATGTTGCATCTAAATATGGAGTAAAGTTAGATGTTGAAGAGGTTGCA
AGGGGAATAGAGGCAATATATGATCCAAGCCAAGCTGGCGCTCACTATCCATCAATGCATCAAGATTTAATACAAAATCA
TCGTCTTACAGAAATAGATTATATAAATGGTTATGTATCAAGAAAAGGTAAAGAGTTTAATATAAATACACCATATAATG
ACTTACTTACTACTCTTGTCATGCAAAAGAGCATACTTATTAAATAA

Protein sequence :
MKIAIVGAGAMGSRYGYMLHEAGNEVMLIDGWKDHVDTINKEGLTVEENGEIKKVKIPAMLPQDAKEIPELIILFTKSMG
LESMLESIKGILGKNTKVLCLLNGLGHNETVAKYVDSKNILMGVTLWTAGLKGPGHVVLTGSGSLEVQNIDPSMEKEAKE
ICDILSNAGLKAHYSENVLFSIWRKACVNGTLNSGCTILDCNIKEFGELKEAPELIRNIIKEFADVASKYGVKLDVEEVA
RGIEAIYDPSQAGAHYPSMHQDLIQNHRLTEIDYINGYVSRKGKEFNINTPYNDLLTTLVMQKSILIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF0517 NP_814296.1 2-dehydropantoate 2-reductase Not tested Not named Protein 1e-76 52
ef0037 AAM75243.1 EF0037 Not tested Not named Protein 9e-77 52