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Name : leuS (CPE0670) Accession : NP_561586.1 Strain : Clostridium perfringens 13 Genome accession: NC_003366 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 834018 - 836468 bp Length : 2451 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGGGTAACTATAGTACTGCCATAGATAAGAAATGGCAAGACAAATGGGCTGAATCAGGCCTTTATAAATTTGATCCAAA TAAAGAAGGAGAGAAACTTTACGTTTTAGAAATGTTCTCATACCCTTCAGGTAGCCAATTACATGCAGGTCACTGGTTTA ACTATGGACCAGTTGATTCATGGGCTAGATTTAAAAGAATGCAAGGATATAATGTATTCCAACCAATGGGATTTGATGCT TTCGGTTTACCTGCTGAAAACTTTGCTATAAAAACAGGAATACATCCTCAAGATTCTACAATAAAAAATATAGCTAAAAT GGAAGAACAATTAAAAGCTATGGGAGCTATGTTTAACTGGGAAAACGAAGTTGTAACTTGCTCACCTGAATATTATAAAT GGACTCAATGGCTATTCCTAAAATTATACGAGAAAGGATTAGCTTATAGAAAAAAAGCTCCTGTAAACTGGTGTCCATCA TGCCAAACAGTTCTTGCTAACGAGCAAGTAGTTGATGGAGCTTGTGAAAGATGTTCAACAGAAGTTACTAAAAAAGATCT TACTCAATGGTTCTTTAAAATAACTGATTATGCTGATGAATTATTAGATAAATTAGATGGTTTAGATTGGCCAGAAAAAA CAGTTTCTATGCAAAAACACTGGATAGGAAGATCAACTGGTTCTCAAGTTAACTTTAAAGTTAAAGATAGCGATTTAAAC TTTGATGTATTCACAACAAGAGTTGATACTTTATGCGGAGTTAGCTATGTTGTTTTAGCTCCTGAAAATCCATTAGTAGA CGAAATAGTTTCAGCTGAACAAAAAGAAGCTGTTGAAAATTATAAAGAAGAAGCTAAAAAACAATCTGATATAGAAAGAC AATCTATTTCAAGAGAAAAAACTGGTGTATTCACTGGTGCATATGCTATTCATCCATTAACAGGCAAAGAAGTTCCTATA TGGGTTGGAGACTACGTTCTAGCAACTTACGGAACTGGAGCTGTTATGGCTGTTCCTGCTCATGATGAAAGAGATTTTGC TTTTGCTGAAAAATTCAACCTTCCAATAAATAGAGTTATAGAAGCTAAAGATGGTAGTGAAACTAACCTTCCATTCTGCG AGCACGGTATATTAGTTAACTCAGGTGAATTTGATGGATTAACTACAGATGAGGCTAAAGAAAAAATAGTTGAAAAACTA TCTTCAATGGGTCTTGGAGAAAAAAAAGTTAACTTTAGATTAAGAGACTGGTTAGTTTCAAGACAAAGATACTGGGGAGC TCCAATTCCTGTAGTTTACTGTGAAGAATGTGGTATAGTTCCTGTACCTGAAAGTCAATTACCAGTTGAATTACCATATG ATGTTGAATTTGCTCCAGATGGAAAATCTCCACTAGCTAAGAGCGAAGCATTTGTTAACACAACTTGCCCTCACTGTGGA AAACCAGCTAAGAGAGAAACTGATACTTTAGATACTTTCGTATGTTCATCATGGTATTACTTAAGATATCCTGATAATAA AAATACTGAGGCTCCATTTAATCCTGAATTAATCAACAAAATGTTACCAGTTGATAAATACGTTGGTGGCCCTGAACATG CTTGTATGCATCTTCTTTACGCAAGATTCATAACTAAAGCCCTAAGAGATATGGGATACCTAAACTTTGATGAACCATTT ACTTCATTAACTCACCAAGGATTAATCTTAGGACCAGACGGATTAAAAATGAGTAAATCAAAAGGAAACACAATATCTCC TGATGATTATATAAAAGAATATGGTGCAGATGTATTTAGAATGTACCTAATGTTTGGTTTTGCTTACACTGAAGGTGGAG CTTGGAGTGATGATGGAATCAAATCTGTAAATAGATTCGTTGAAAGAATTGAAAGAATTATAGATACTGCTAGAGAAGCA ATCTCAAAAGGTGAAAATAATAAAACTACAATGGATAAGGCTGAAAAAGAGCTTAACTATTGGAGACATAATACTATAAA ATCTGTTACAGATGATACAGATAAACTTCAATTTAATACAGCAATAGCTAGAATGATGGAATTCATAAATGCTCTATCTA AATATACTCAAGAGAAAGAAATGAATCTTGATTTCTTAAAAGATGTAGTTTCTGATTATTTAAGATTATTAGCACCATTT GCACCTCACTTCAGTGAAGAACAATGGAACTTACTTGGAAATTCATACTCAATCTTCAATGAAGCATGGCCAAAATTTGA CCCTAAAGCTTTAGTTAAAGACGAAGTTGAAATAGCTATCCAAGTTAACGGAAAAATCAAAAACAAAATAATGGTTTCTT CTGATTTAGATGAAGAAGGAATAAAAGCCGCTGCTTTAGCTGATGAGAAAATCATAGCTTCAACAGAAGGAAAAACAGTT GTAAAAGTAATAGTTATAAAAGGTAGACTTGTAAATATAGTTGTTAAATAA Protein sequence : MGNYSTAIDKKWQDKWAESGLYKFDPNKEGEKLYVLEMFSYPSGSQLHAGHWFNYGPVDSWARFKRMQGYNVFQPMGFDA FGLPAENFAIKTGIHPQDSTIKNIAKMEEQLKAMGAMFNWENEVVTCSPEYYKWTQWLFLKLYEKGLAYRKKAPVNWCPS CQTVLANEQVVDGACERCSTEVTKKDLTQWFFKITDYADELLDKLDGLDWPEKTVSMQKHWIGRSTGSQVNFKVKDSDLN FDVFTTRVDTLCGVSYVVLAPENPLVDEIVSAEQKEAVENYKEEAKKQSDIERQSISREKTGVFTGAYAIHPLTGKEVPI WVGDYVLATYGTGAVMAVPAHDERDFAFAEKFNLPINRVIEAKDGSETNLPFCEHGILVNSGEFDGLTTDEAKEKIVEKL SSMGLGEKKVNFRLRDWLVSRQRYWGAPIPVVYCEECGIVPVPESQLPVELPYDVEFAPDGKSPLAKSEAFVNTTCPHCG KPAKRETDTLDTFVCSSWYYLRYPDNKNTEAPFNPELINKMLPVDKYVGGPEHACMHLLYARFITKALRDMGYLNFDEPF TSLTHQGLILGPDGLKMSKSKGNTISPDDYIKEYGADVFRMYLMFGFAYTEGGAWSDDGIKSVNRFVERIERIIDTAREA ISKGENNKTTMDKAEKELNYWRHNTIKSVTDDTDKLQFNTAIARMMEFINALSKYTQEKEMNLDFLKDVVSDYLRLLAPF APHFSEEQWNLLGNSYSIFNEAWPKFDPKALVKDEVEIAIQVNGKIKNKIMVSSDLDEEGIKAAALADEKIIASTEGKTV VKVIVIKGRLVNIVVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 3e-176 | 47 |
