Gene Information

Name : CPE0642 (CPE0642)
Accession : NP_561558.1
Strain : Clostridium perfringens 13
Genome accession: NC_003366
Putative virulence/resistance : Virulence
Product : DNA-binding response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 804031 - 804726 bp
Length : 696 bp
Strand : +
Note : similar to pir:D72228 response regulator DrrA from Thermotoga maritima (strain MSB8) (247 aa); 50.6% identity in 231 aa overlap

DNA sequence : 
ATGACAAATAAAAAAGTCCTAATAGTAGATGATGAGGAACATATTAGAGAACTTATAAAATTTAATTTAAAAAAAGAGGG
ATATGATACAGAGGTTGCTGTTAATGGAACTGAAGCTCTAAAGGTTATAAGAGAAATTAAGTTTGATTTAATACTTTTAG
ATTTAATGCTTCCAGAAATAGATGGCTTAGAAGTATGTAAAGAAATTAGAAGAAATGAAGAAACTTCAGATATTCCAGTA
ATGATGATTACAGCAAAGGGGGAAGAGTTTGATAAAGTATTAGGCTTAGAACTTGGAGCAGATGATTATATAACAAAGCC
ATTTTCAATAAGAGAACTTATGGCTAGAGTAAAAGCTTTACTCAGAAGAAGTAATGTTAAAAAAGAAGAAAATATAATTA
AATTTGGTGATGTAGTAGTTAATTTTAAAACAAGAGAAGTAACAAAAGGAACTCAAAATGTAGAATTAACATTAAAAGAG
TTTGAATTATTAAAGCTTCTTATAAAGAATAAGGGCAATATATTAACTAGAGAACTTTTGCTTGATAAAATTTGGGGATA
TGAATACATAGGTGAAACAAGAACAGTAGATGTTCATATTAGACATTTACGTAAAAAGATTGAAAGCGATGATAAAAATC
CTCAATATATTCAAACTATAAGAGGCGTTGGGTATAAGTTTACAAGTAATGAGTAA

Protein sequence : 
MTNKKVLIVDDEEHIRELIKFNLKKEGYDTEVAVNGTEALKVIREIKFDLILLDLMLPEIDGLEVCKEIRRNEETSDIPV
MMITAKGEEFDKVLGLELGADDYITKPFSIRELMARVKALLRRSNVKKEENIIKFGDVVVNFKTREVTKGTQNVELTLKE
FELLKLLIKNKGNILTRELLLDKIWGYEYIGETRTVDVHIRHLRKKIESDDKNPQYIQTIRGVGYKFTSNE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 2e-34 42
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 5e-34 42
vanRB YP_001698483.1 regulatory protein Not tested Not named Protein 3e-27 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CPE0642 NP_561558.1 DNA-binding response regulator NC_012469.1.7686381. Protein 2e-47 54
CPE0642 NP_561558.1 DNA-binding response regulator NC_012469.1.7685629. Protein 6e-45 54
CPE0642 NP_561558.1 DNA-binding response regulator NC_002952.2859905.p0 Protein 9e-44 52
CPE0642 NP_561558.1 DNA-binding response regulator NC_007622.3794472.p0 Protein 9e-44 52
CPE0642 NP_561558.1 DNA-binding response regulator NC_002758.1121668.p0 Protein 1e-43 52
CPE0642 NP_561558.1 DNA-binding response regulator NC_009641.5332272.p0 Protein 1e-43 52
CPE0642 NP_561558.1 DNA-binding response regulator NC_013450.8614421.p0 Protein 1e-43 52
CPE0642 NP_561558.1 DNA-binding response regulator NC_007793.3914279.p0 Protein 1e-43 52
CPE0642 NP_561558.1 DNA-binding response regulator NC_003923.1003749.p0 Protein 1e-43 52
CPE0642 NP_561558.1 DNA-binding response regulator NC_002745.1124361.p0 Protein 1e-43 52
CPE0642 NP_561558.1 DNA-binding response regulator NC_009782.5559369.p0 Protein 1e-43 52
CPE0642 NP_561558.1 DNA-binding response regulator NC_002951.3237708.p0 Protein 1e-43 52
CPE0642 NP_561558.1 DNA-binding response regulator HE999704.1.gene2815. Protein 8e-41 50
CPE0642 NP_561558.1 DNA-binding response regulator AE016830.1.gene1681. Protein 7e-41 47
CPE0642 NP_561558.1 DNA-binding response regulator NC_014475.1.orf0.gen Protein 7e-34 46
CPE0642 NP_561558.1 DNA-binding response regulator NC_005054.2598277.p0 Protein 7e-34 46
CPE0642 NP_561558.1 DNA-binding response regulator AF155139.2.orf0.gene Protein 1e-33 44
CPE0642 NP_561558.1 DNA-binding response regulator AE000516.2.gene3505. Protein 2e-38 44
CPE0642 NP_561558.1 DNA-binding response regulator NC_013450.8614146.p0 Protein 9e-35 43
CPE0642 NP_561558.1 DNA-binding response regulator NC_002951.3238224.p0 Protein 9e-35 43
CPE0642 NP_561558.1 DNA-binding response regulator NC_007793.3914065.p0 Protein 9e-35 43
CPE0642 NP_561558.1 DNA-binding response regulator NC_002758.1121390.p0 Protein 9e-35 43
CPE0642 NP_561558.1 DNA-binding response regulator NC_010079.5776364.p0 Protein 9e-35 43
CPE0642 NP_561558.1 DNA-binding response regulator NC_002952.2859858.p0 Protein 9e-35 43
CPE0642 NP_561558.1 DNA-binding response regulator NC_007622.3794948.p0 Protein 9e-35 43
CPE0642 NP_561558.1 DNA-binding response regulator NC_003923.1003417.p0 Protein 9e-35 43
CPE0642 NP_561558.1 DNA-binding response regulator HE999704.1.gene1202. Protein 3e-27 42
CPE0642 NP_561558.1 DNA-binding response regulator FJ349556.1.orf0.gene Protein 5e-34 42
CPE0642 NP_561558.1 DNA-binding response regulator DQ212986.1.gene4.p01 Protein 4e-30 42
CPE0642 NP_561558.1 DNA-binding response regulator AE015929.1.gene1106. Protein 1e-31 41
CPE0642 NP_561558.1 DNA-binding response regulator AM180355.1.gene1830. Protein 9e-29 41
CPE0642 NP_561558.1 DNA-binding response regulator BAC0596 Protein 4e-31 41
CPE0642 NP_561558.1 DNA-binding response regulator BAC0039 Protein 3e-31 41
CPE0642 NP_561558.1 DNA-binding response regulator CP001138.1.gene2239. Protein 4e-31 41
CPE0642 NP_561558.1 DNA-binding response regulator CP000034.1.gene2186. Protein 3e-31 41
CPE0642 NP_561558.1 DNA-binding response regulator NC_002695.1.916589.p Protein 3e-31 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CPE0642 NP_561558.1 DNA-binding response regulator VFG1563 Protein 1e-34 42
CPE0642 NP_561558.1 DNA-binding response regulator VFG1702 Protein 2e-34 42