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Name : pykA (CPE0362) Accession : NP_561278.1 Strain : Clostridium perfringens 13 Genome accession: NC_003366 Putative virulence/resistance : Virulence Product : pyruvate kinase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0469 EC number : - Position : 462655 - 464058 bp Length : 1404 bp Strand : + Note : similar to sp:KPYK_BACSU PYRUVATE KINASE (EC 2.7.1.40) (PK) (VEGETATIVE PROTEIN 17) (VEG17) from Bacillus subtilis (585 aa); 56% identity in 466 aa overlap. 1 transmembrane region was found by PSORT DNA sequence : ATGAGAAGAACAAAATTAGTATGCACTATCGGACCAGCTAGTGAAAACGAAGAAATCTTAACAAAAATAATCGAAGCAGG TATGAACGCTTCAAGACACAATTTCTCACATGGTGACCATGAAGAACATAAAGGAAGAATGGTTAAAGTAAGAGAAATAT CAAAAAAATTAGGTAAAGAAGTAGCTATATTATTAGATACTAAAGGACCTGAAATAAGAACTGGAAAATTCGAGCCAAGC AAAGTTGAATTAACTGCTGGAACTGAATTTACTATATATGCTGGAGCAGAAGACGTAATAGGAGACACTACTAAGTGTTC AGTTACATATGCTGGATTAGCTAAAGACGTTAAAGCTGGAGATACTATCTTAATAGACGACGGTTTAGTTGGATTAGAAG TTGTATCTGTAGAAGGAAACGCTGTTAAATGTGTAGTAAGAAACACTGGATTAGTTGGAACTCACAAAGGAGTTAACGTT CCTGGAGTATCAATAAAATTACCAGCTATGACTGATAAAGATAGAGCTGACTTAATATTCGGTTGTGAAATGGGCGTTAA CATGGTTGCTGCTTCATTCATAAGAAAAGCAGAAGACGTTAAAGCTATAAGAGAAGTATTAGTTGCTAACGGTGGAGCTG ATATACAAATATTCTCAAAAATCGAAAACCAAGAAGGTGTTGATAACATAGATGCTATCATCGAAGCTTCAGACGGTATC ATGGTAGCTAGAGGAGACCTTGGTGTTGAAATACCAATGGAAGACGTTCCTTCAGTTCAAAAAATGATCATCGAAAAATG TAACAATGCTGGAAAACCAGTTATAACTGCTACTCAAATGTTAGACTCAATGATGAGAAACCCAAGACCAACAAGAGCTG AGGTTTCAGACGTAACTAACGCTATCTTAGATGGTACTGATGCTATCATGTTAAGTGGTGAGTCAGCTAACGGAAGCTGG CCAGTAGAAGCTGTTGAAACTATGGTTAAAATAGCTACTAAATCAGAAGAAATGTTAAGCTACGAATTAGCTTCATCAAA AGCTAAAAAACATATACCAGCTGTACCAGGAGTTATCTCAAGAGCTGCTTGTAATGCTGCACACGAGTTAAAATCAGCTG CTATAGTTTCATTAACTCAATCAGGAGCTACTGCTAAGAGAATATCTCAATGCAGACCAGATGCACCAATCGTTACTGTA ACTCCAAACGAAAGAGTTGCTAAGAAAGTTGCTTTATGCTTCGGTGTTTACCCAGTTGTTGCTGAAAATGCTACAATGGA AAACGCTGTTGAAATAGCTAAAAATGCTGGATTCGTTAAAGCTAATGACACTGCTGTAGTTGTTGCAGGTGTACCAGCTA ACGAAGGAAACACTAACATAGTAAAAGTTGAAGTTGTAAAATAA Protein sequence : MRRTKLVCTIGPASENEEILTKIIEAGMNASRHNFSHGDHEEHKGRMVKVREISKKLGKEVAILLDTKGPEIRTGKFEPS KVELTAGTEFTIYAGAEDVIGDTTKCSVTYAGLAKDVKAGDTILIDDGLVGLEVVSVEGNAVKCVVRNTGLVGTHKGVNV PGVSIKLPAMTDKDRADLIFGCEMGVNMVAASFIRKAEDVKAIREVLVANGGADIQIFSKIENQEGVDNIDAIIEASDGI MVARGDLGVEIPMEDVPSVQKMIIEKCNNAGKPVITATQMLDSMMRNPRPTRAEVSDVTNAILDGTDAIMLSGESANGSW PVEAVETMVKIATKSEEMLSYELASSKAKKHIPAVPGVISRAACNAAHELKSAAIVSLTQSGATAKRISQCRPDAPIVTV TPNERVAKKVALCFGVYPVVAENATMENAVEIAKNAGFVKANDTAVVVAGVPANEGNTNIVKVEVVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 5e-100 | 52 |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 5e-100 | 52 |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-100 | 52 |
| pykF | CAA68205.1 | pyruvate kinase like protein | Not tested | SPI-2 | Protein | 5e-99 | 51 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| pykA | NP_561278.1 | pyruvate kinase | VFG0479 | Protein | 2e-100 | 52 |
