Gene Information

Name : polA (CPE1994)
Accession : NP_562910.1
Strain : Clostridium perfringens 13
Genome accession: NC_003366
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : -
Position : 2283149 - 2285749 bp
Length : 2601 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGAAAAGATTATTGATATTAGATGGGAACAGTCTTTTAAATAGAGCCTTTTATGCTGTGCCTTTGCTTAGCAATAGTGA
AGGAACTCATACAAATGCTATTTATGGTTTTACAAATATGCTTTTTAAGATGAGAGAGGATATAAAACCTGATTATATAG
TTTGTACTTTTGATAAAAAAGCACCAACTTTTAGACATTTAGAGTATGGGGATTATAAGGCTGGAAGAAAGAAAATGCCT
CCTGAGTTAGCAGAGCAGTTTCCTATTGTTAAGGAAATGTTAAAGTTATTTTCAATAACAACTTACGAATTAGATGGATT
CGAAGCAGATGATATTATAGGAAGTTTAGCTAAGGTGGCTGAAGGTGAAGGAATCGAAGTGTATATTATGACTGGAGATA
AGGATGCCCTTCAACTAGCAGCTAAGGATATAAACGTATGTATAACTAAGAAGGGTGTTTCTGAAATAGAAGTTTATAAC
TATGATAGAATGGTTGAAGAATATGGAGTTACTCCTACTCAGTTTATAGATGTTAAAGGACTTATGGGAGATAAATCTGA
TAATATTCCAGGGGTACCAGGAGTAGGAGAAAAAACAGCCTTTAAATTAATAAAAGAGTATGGTTCAGTAGAGGCAGTTT
TAGAAAATATAGATAACATAAGTGGTAAAAAGTTAAAAGAAAATTTAACTGAGTACAGCGAACAGGCTATATTCTCTAAA
AAGTTAGCTACTATTATGACTAATGTTCCTATAGATTTTGATTTAGATGAGATTAAATCAAAGGATGATTATAATAAAGA
TCAGTTAAAAGCTTTATTTACAAAGCTTCAAATGAAATCTATATTAGATAAATTATCAAATGGGGAAGAAGAAGAGCCAG
AAATAGAAGTTAAAATAACTAATATAGAAAATAATAAAGAATTAGAAGATTTATTTAAGAATATAAACGAAGAAGTATAT
ATTAATTTTACTTACTTAAATAAAGAAAAGTATTCTACTATAGAGATTGATAAAATATTTATTAATTATGATGAGAAAAA
TTATTTAATTAACTTTAAAGAGTTAGTAAAAGAAGAGGAGAATATTAAATCCTTTAAAGAATTTTTTGAGAATGAAGCTA
TATTAAAAAATGGCTATAGTATAAAAAATGCCTTAACAGCATTAAAAAAATTAGGAATAGATTTTAATGGATTAGCCTTT
GATTGTGAATTAGCAGCATATTTAATAGATTCATCTAAGGGAGAATATACTCTTTTATCCTTAATAAATAACTATCTTTC
AAAATTCCCTAATGTAAAAGAGGGAGAGGAAGACTTAGTTGGAATTACATTTATGAAAGAGTTGACTTTAGTTCTAAAGA
AAAAAATAGAAGAAGAGAAAATGGAAAGACTTATGTATGATATTGAGCTTCCTTTAGAAACAGTTTTATCTTCTATGGAA
TCAATAGGATTTAAAGTAAATAAAGATATTTTAGATGAGTTATCTATTAAGTTTAAAAGAGAGCTAGAAGAAACACAAAA
AGAGATCTTTGAACTTGCAGATGAAGAGTTCAACATAAATTCTCCAAAACAATTAGGTAAGATATTATTTGAAAAATTAG
ATTTACCAGTTATAAAGAAAACTAAAACTGGCTATTCAACTAACGCAGAAGTTTTAGAAAAGCTTAAGGACAAACATCCT
ATAATAGAAAAAATAACATATTTTAGACAGCTTTCAAAAATATATTCAACTTATGTTGAAGGATTAAAGGCTGTTATAGA
TACAGATGGTTCTATACATTCAACATTTAATCAAACTGTAACTACTACAGGTAGACTTTCATCAACAGAGCCTAACCTTC
AAAATATACCTATAAAATACGAAATGGGTAGAGAAATAAGAAAGGTATTTATACCAAAAAAAGAAGGAGATTTATTAATA
TCAGCTGACTACTCACAAATAGAACTTAGAGTTTTAGCTCATATTTCTGGTGATGAAAATATGATAGATGCATTTAATCA
TCATTCAGATATACACACTAAGACTGCTTCTGAAGTGTTTAAAGTGCCAGTTGAAGAGGTAACTCCATTAATGAGAAGTA
GGGCTAAGGCAGTAAACTTTGGTATAGTATATGGAATAGGAGATTTTAGTCTTTCTCAGGATTTAAATATTTCAAGAAAA
GAAGCTAAAGAATATATGGATATATATTTTGAAAGATATCCAAAAATTAAAGAGTATATTTCTAAGGTTATTCATGAAGC
TCAAACAAAAGGATATGTATTAACTATGTTAAATAGAAGAAGATATATACCTGAAGCAAATGCTTCAAATAAAATAGTAA
AAGCTTTAGGAGAAAGACTTGCAATGAATGCTCCAATACAAGGAACAGCAGCAGATATAATAAAGCTTGCTATGGTAAAT
GTATATAACAAGTTAAAAGAATTAAATTTAAATAGTAAGTTAATATTACAGGTTCACGATGAACTTATAATAAATGTTGT
AAAAGGAGAATTAGATATTGTTAAGAAACTTCTAAAAGAGGAAATGGAAAATACAATTAAATTAAGTGTACCATTAGATG
TTGATGTTAATGTTGGAGAAGATTGGTATAGGTTAAAATAA

Protein sequence :
MKRLLILDGNSLLNRAFYAVPLLSNSEGTHTNAIYGFTNMLFKMREDIKPDYIVCTFDKKAPTFRHLEYGDYKAGRKKMP
PELAEQFPIVKEMLKLFSITTYELDGFEADDIIGSLAKVAEGEGIEVYIMTGDKDALQLAAKDINVCITKKGVSEIEVYN
YDRMVEEYGVTPTQFIDVKGLMGDKSDNIPGVPGVGEKTAFKLIKEYGSVEAVLENIDNISGKKLKENLTEYSEQAIFSK
KLATIMTNVPIDFDLDEIKSKDDYNKDQLKALFTKLQMKSILDKLSNGEEEEPEIEVKITNIENNKELEDLFKNINEEVY
INFTYLNKEKYSTIEIDKIFINYDEKNYLINFKELVKEEENIKSFKEFFENEAILKNGYSIKNALTALKKLGIDFNGLAF
DCELAAYLIDSSKGEYTLLSLINNYLSKFPNVKEGEEDLVGITFMKELTLVLKKKIEEEKMERLMYDIELPLETVLSSME
SIGFKVNKDILDELSIKFKRELEETQKEIFELADEEFNINSPKQLGKILFEKLDLPVIKKTKTGYSTNAEVLEKLKDKHP
IIEKITYFRQLSKIYSTYVEGLKAVIDTDGSIHSTFNQTVTTTGRLSSTEPNLQNIPIKYEMGREIRKVFIPKKEGDLLI
SADYSQIELRVLAHISGDENMIDAFNHHSDIHTKTASEVFKVPVEEVTPLMRSRAKAVNFGIVYGIGDFSLSQDLNISRK
EAKEYMDIYFERYPKIKEYISKVIHEAQTKGYVLTMLNRRRYIPEANASNKIVKALGERLAMNAPIQGTAADIIKLAMVN
VYNKLKELNLNSKLILQVHDELIINVVKGELDIVKKLLKEEMENTIKLSVPLDVDVNVGEDWYRLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 9e-155 44