Gene Information

Name : metB (CPE0176)
Accession : NP_561092.1
Strain : Clostridium perfringens 13
Genome accession: NC_003366
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 227846 - 229000 bp
Length : 1155 bp
Strand : +
Note : similar to gp:AB028629_1 cystathionine beta-synthase from Clostridium perfringens (351 aa); 96.6% identity in 351 aa overlap. 1 transmembrane region was found by PSORT

DNA sequence : 
ATGAAGAAGAATTCTTTATTAATACATGGGGGTATAAGTATAGATGAAAAAACTGGGGCAGTAAATATTCCAATATATCA
AACATCCACATACAAGCAAAGATCTTTTGGGGAAAATAGTGGATATGAATATTCAAGAACAGGAAACCCAACTAGGGAAT
CATTAGAAAAGTTAATTGCAGATATAGAATATGGAAAAAGAGGATTTGCCTTTGCATCAGGTCTTGCAGCAATTACTGCA
GTATTAAGTTTATTTAAAAGTGGAGATAAATTATTAATTACTAATAATCTTTACGGTGGAACATTTAGAGTAATTGATAA
GATATTCTCTAACTTTGGGATAGGTTATGAAATAATTGATGACTTTACCAATATTGAAGAAAAAATTGACAAGAGTGTTA
AAGCTATTTATATAGAAACACCTACAAATCCTCTGTTAGATGTCATAGATATAAAAATAGCATCAGATAAAGCTAAAAAG
TATAATTTATTAACAATAGTAGATAACACATTTATGACTCCATATTTTCAAAATCCATTAAATCTTGGGGCAGATATAGT
TATTCATTCAGCAACTAAATATCTTGGGGGGCACAGTGATTTAGTTGCTGGGCTTGTAGTTGTGAAAGATGAAGAGCTTG
GAGAGAAAATACACTTTATACAAAACTCTACTGGTGGAATACTTCAACCTTTTGATAGCTTCTTACTAATAAGAGGAATC
AAAACTTTATCAGTAAGAATGGATAGACATGAATTAAATGCTAATTTTATAGCTGAAAAGTTAGGTGATTTAGAGGGGAT
AGATAATGTATATTATCCAGGACTTAAAACTCATATTGGACATGACATACAAAAGAAACAAGCTTCAGGTTTTGGGGGAA
TAATCTCTTTCACTTTAAATAAGAAATATAATTATGAGAAGTTCTTTAATAGTTTAGAACTTATAACCTTTGGGGAAAGC
TTAGGTGGAGTGGAGTCTTTGGCATGTCACCCAGCTTCTATGACTCATGCAGCTATGCCATTAGAACTTAGAGAACGTAT
AGGAATAACAGATAGGTTAATAAGAATTTCAGTTGGTATAGAAGATAAAGAGGATATTTTAGAAGATATACAAAAAGCTT
TAGTAAAGGCTGGTGATAAAAATGAAATATTATAA

Protein sequence : 
MKKNSLLIHGGISIDEKTGAVNIPIYQTSTYKQRSFGENSGYEYSRTGNPTRESLEKLIADIEYGKRGFAFASGLAAITA
VLSLFKSGDKLLITNNLYGGTFRVIDKIFSNFGIGYEIIDDFTNIEEKIDKSVKAIYIETPTNPLLDVIDIKIASDKAKK
YNLLTIVDNTFMTPYFQNPLNLGADIVIHSATKYLGGHSDLVAGLVVVKDEELGEKIHFIQNSTGGILQPFDSFLLIRGI
KTLSVRMDRHELNANFIAEKLGDLEGIDNVYYPGLKTHIGHDIQKKQASGFGGIISFTLNKKYNYEKFFNSLELITFGES
LGGVESLACHPASMTHAAMPLELRERIGITDRLIRISVGIEDKEDILEDIQKALVKAGDKNEIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-87 51
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-88 51

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB NP_561092.1 cystathionine beta-lyase BAC0207 Protein 5e-58 42