Gene Information

Name : serS (CPE0014)
Accession : NP_560930.2
Strain : Clostridium perfringens 13
Genome accession: NC_003366
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 21268 - 22545 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATTTAAAAAAGTTAAGAAGTAATACTGAAGAAGTGAAAAAAGCTTTATCTAATAGAGGAGAAGACTTTGATGT
AAATGTTATAGACGAAGTTATAGCTTTAGATGAAGAAAGAAGAAAAATTTTAGTTGATGTTGAGGCTTTAAAGAAACAAA
GAAATGAAGTATCAGCTGAAATTCCAAAGAGAAAAAAAGCTGGAGAAGACGTTACAGAAGTAATGGCTGAAATGAGAGAA
ATAGGAGATAAAATAAAGGCTGATGATGCTAAAGTTGCTGAGTTAAACGATAAAATTAACTATATCATGCTAAGAATTCC
TAATATACCAAACCCAGCTGTTCCAGAAGGGGAAACTGATGAGGACAATGTTGAAATAAAAAGATGGGGAGAACCTACTA
AATTCAACTTTGAACCAAAAGCACACTGGGATTTAGGAACAGATTTAGATCTTTTAGACTTCGAAAGAGGTGGAAAGGTT
GCTGGATCAAGATTTACAGTTTACAAAGGAATGGGTGCTAGATTAGAGAGATCTATAATAAACTACTTCTTAGATAAACA
CACATTTGAAAATGGATACACTGAAGTATTACCACCATACATGGTAAATAGAGATAGTATGACTGGTACTGGTCAACTTC
CAAAATTCGAAGAAGATGCTTTCAAAGTAGAAAACAATGGATATTTCTTAATACCAACAGCTGAGGTTCCTGTAACTAAT
ATGTACAGAAATGAAACTTTAGAGGGAGATAAACTTCCAATAAAACATGCTGCATATAGTGCTTGTTTTAGAGCGGAAGC
TGGTTCAGCAGGAAGAGATACAAGAGGTCTTATAAGACAACACCAATTTAATAAAGTTGAGTTAGTTAAGTTCTGTAAAC
CTGAGCAAAGCTATGAAGAATTAGATAAATTAGTTCAAGATGCTGAATCTGTATTACAAGGTTTAGGATTACCATATAGA
ATAGTTAGAATATGTAAAGGTGATTTAGGATTCACTGCTGCATTAAAATATGATATAGAAGTTTGGATGCCAAGCTACAA
TAGATATGTTGAAATTTCAAGTTGTTCAAACTTTGAAGATTTCCAAGCTAGAAGAGCTAACATTAAATATAAAAATTCTC
CAAAGGAAAAACCACAATTTGTTCATACATTAAATGGATCAGGGGTTGCTATTGGAAGAACTGTAGCTGCTATATTAGAA
AACTATCAACAAGAAGATGGATCAGTAGTTATACCAGAAGCTTTAAAAGAATATATGAGATGTGATTTACTAAAATAA

Protein sequence :
MLDLKKLRSNTEEVKKALSNRGEDFDVNVIDEVIALDEERRKILVDVEALKKQRNEVSAEIPKRKKAGEDVTEVMAEMRE
IGDKIKADDAKVAELNDKINYIMLRIPNIPNPAVPEGETDEDNVEIKRWGEPTKFNFEPKAHWDLGTDLDLLDFERGGKV
AGSRFTVYKGMGARLERSIINYFLDKHTFENGYTEVLPPYMVNRDSMTGTGQLPKFEEDAFKVENNGYFLIPTAEVPVTN
MYRNETLEGDKLPIKHAAYSACFRAEAGSAGRDTRGLIRQHQFNKVELVKFCKPEQSYEELDKLVQDAESVLQGLGLPYR
IVRICKGDLGFTAALKYDIEVWMPSYNRYVEISSCSNFEDFQARRANIKYKNSPKEKPQFVHTLNGSGVAIGRTVAAILE
NYQQEDGSVVIPEALKEYMRCDLLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-120 58