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Name : pfoA (CPE0163) Accession : NP_561079.1 Strain : Clostridium perfringens 13 Genome accession: NC_003366 Putative virulence/resistance : Virulence Product : perfringolysin O Function : - COG functional category : - COG ID : - EC number : - Position : 209028 - 210530 bp Length : 1503 bp Strand : + Note : similar to sp:TACY_CLOPE PERFRINGOLYSIN O PRECURSOR (THETA-TOXIN) (THIOL-ACTIVATED CYTOLYSIN) from Clostridium perfringens (500 aa); 99.8% identity in 500 aa overlap. N-terminal signal sequence was found by PSORT DNA sequence : ATGATAAGATTTAAGAAAACAAAATTAATAGCAAGTATTGCAATGGCTTTATGTCTGTTTTCTCAACCAGTAATCAGTTT CTCAAAGGATATAACAGATAAAAATCAAAGTATTGATTCTGGAATATCAAGCTTAAGTTACAATAGAAATGAAGTTTTAG CTAGTAATGGAGATAAAATTGAAAGTTTTGTTCCAAAGGAAGGTAAAAAGACTGGTAATAAATTTATAGTTGTAGAACGT CAAAAAAGATCCCTTACAACATCACCAGTAGATATATCAATAATTGATTCTGTAAATGACCGTACATATCCAGGAGCATT ACAACTTGCAGATAAAGCCTTTGTGGAAAATAGACCTACAATCTTAATGGTAAAAAGAAAGCCTATTAACATTAATATAG ATTTACCAGGATTAAAGGGTGAAAATAGTATAAAGGTTGATGATCCAACCTATGGAAAAGTTTCTGGAGCAATTGATGAG TTAGTGTCTAAGTGGAATGAAAAGTATTCATCTACACATACTTTACCAGCAAGAACTCAATATTCAGAATCTATGGTTTA TAGTAAATCACAAATATCAAGTGCCCTTAATGTTAATGCTAAAGTCCTTGAAAACTCACTTGGAGTAGACTTTAATGCAG TAGCAAACAATGAGAAAAAAGTTATGATTTTAGCATATAAACAAATATTCTATACAGTAAGTGCAGACTTACCTAAGAAT CCATCAGATCTTTTTGATGACAGTGTTACATTTAATGATTTAAAACAAAAGGGAGTAAGTAATGAAGCACCTCCACTTAT GGTTTCAAATGTAGCTTATGGAAGAACTATATATGTTAAGTTAGAAACTACTTCTAGTAGTAAAGATGTACAAGCTGCTT TCAAAGCTCTTATAAAGAACACTGATATAAAAAATAGTCAACAATATAAAGATATTTATGAAAATAGTTCCTTCACAGCA GTAGTTTTAGGAGGAGATGCACAAGAACATAACAAAGTTGTAACTAAGGACTTTGATGAAATAAGAAAAGTAATTAAAGA CAATGCAACTTTTAGTACAAAAAACCCAGCATATCCAATATCTTATACTAGTGTTTTCTTAAAAGATAACTCAGTTGCTG CTGTTCACAATAAAACAGATTATATAGAAACAACTTCTACAGAGTATTCTAAGGGAAAAATAAACTTAGATCATAGTGGA GCCTATGTTGCACAGTTTGAAGTAGCATGGGATGAAGTTTCATATGACAAAGAAGGAAATGAAGTTTTAACTCATAAAAC ATGGGATGGAAATTATCAAGATAAAACAGCTCACTATTCAACAGTAATACCTCTTGAAGCCAATGCAAGAAATATAAGAA TAAAGGCAAGAGAGTGTACAGGTCTTGCTTGGGAATGGTGGAGAGATGTTATAAGTGAATATGATGTTCCATTAACAAAT AATATAAATGTTTCAATATGGGGAACTACTTTATACCCTGGATCTAGTATTACTTACAATTAA Protein sequence : MIRFKKTKLIASIAMALCLFSQPVISFSKDITDKNQSIDSGISSLSYNRNEVLASNGDKIESFVPKEGKKTGNKFIVVER QKRSLTTSPVDISIIDSVNDRTYPGALQLADKAFVENRPTILMVKRKPININIDLPGLKGENSIKVDDPTYGKVSGAIDE LVSKWNEKYSSTHTLPARTQYSESMVYSKSQISSALNVNAKVLENSLGVDFNAVANNEKKVMILAYKQIFYTVSADLPKN PSDLFDDSVTFNDLKQKGVSNEAPPLMVSNVAYGRTIYVKLETTSSSKDVQAAFKALIKNTDIKNSQQYKDIYENSSFTA VVLGGDAQEHNKVVTKDFDEIRKVIKDNATFSTKNPAYPISYTSVFLKDNSVAAVHNKTDYIETTSTEYSKGKINLDHSG AYVAQFEVAWDEVSYDKEGNEVLTHKTWDGNYQDKTAHYSTVIPLEANARNIRIKARECTGLAWEWWRDVISEYDVPLTN NINVSIWGTTLYPGSSITYN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| slo | YP_281505.1 | streptolysin O | Virulence | Not named | Protein | 3e-156 | 67 |
| hly | AAA69525.1 | listeriolysin O | Virulence | LIPI-1 | Protein | 5e-104 | 44 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| pfoA | NP_561079.1 | perfringolysin O | VFG2275 | Protein | 0.0 | 100 |
| pfoA | NP_561079.1 | perfringolysin O | VFG0976 | Protein | 1e-156 | 67 |
| pfoA | NP_561079.1 | perfringolysin O | VFG1363 | Protein | 3e-110 | 47 |
| pfoA | NP_561079.1 | perfringolysin O | VFG0074 | Protein | 2e-104 | 44 |
