Gene Information

Name : hemC (PAE0580)
Accession : NP_558693.1
Strain : Pyrobaculum aerophilum IM2
Genome accession: NC_003364
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 311160 - 312053 bp
Length : 894 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCGACTCAAAGTGGCAACTAGGGGGAGCAGATTGAGCCTTCTGCAGACGGAGGAGTTCTTAGCGCAGATAAAGGCAGT
TGAGCCGCGCGTGGATTTTGAGATTAAGATCGTCAAAACCACGGGGGATTTAGTACAAGACAAGCCTCTGTTTCAAATAG
GCGTCAAGGGGATTTTTGAAAAAGAGGTTAACCTCGCCGTTTTAAAAGGCGAGGCCGACATTGCCATTCACTCATTAAAA
GACCTCCCCTCCGAGATCTCCCCAGGGCTCGTCCTTGCAGGTTTCTCCAAGAGGACTTTGCCGTATGACGCAGTTGTCAG
CGCCGTCGGCTATGACTTAGAGAGCCTCCCGAAAGGGGCTCTTGTCGGCACGTCCAGCGTGCGGCGGGCGGAGTTTATTA
AATCGTTGAGGCCCGACGTGAGAATTGAGCCTCTGAGGGGCAACGTGGACACTAGAGTGCAGAAAATTCTTCAAGGCAAG
TATGACGCCGCAGTTATGGCCGCCGCCGGCATATTGAGGCTTTACGGGGAGTCGCCCCCCGTAAAGCTCTCACTACTCCG
CCCAGAGTTGTTGCCTCCCCCGCCGGGCCAGGGCATTGTGGCGGCGGTGGTCAGGGAGGGAGAGGGCTGGCTGATTGACT
TATTGAAAAAAGCCAGCGATCCGAGGGCCACAGTGGAGGCACTCGCCGAGAGGGAGTTTTTAAAGAACGTGGGGGCTGGA
TGCCACGTCGCCGTGGGGGGGACAGCGTTTAGTAGAAACGGCTATATTGAATTCATTGCTGGCTACGCCGCGAGTGGAAA
GAGGTTTGTGGTAAAGCTCTTCGGCGAGGATCCGGTTGAAGTGGGGAGACGCGCCGCCGAGGAGATCAAACGAGTCGCCG
CTAGCGTTAGATAG

Protein sequence :
MRLKVATRGSRLSLLQTEEFLAQIKAVEPRVDFEIKIVKTTGDLVQDKPLFQIGVKGIFEKEVNLAVLKGEADIAIHSLK
DLPSEISPGLVLAGFSKRTLPYDAVVSAVGYDLESLPKGALVGTSSVRRAEFIKSLRPDVRIEPLRGNVDTRVQKILQGK
YDAAVMAAAGILRLYGESPPVKLSLLRPELLPPPPGQGIVAAVVREGEGWLIDLLKKASDPRATVEALAEREFLKNVGAG
CHVAVGGTAFSRNGYIEFIAGYAASGKRFVVKLFGEDPVEVGRRAAEEIKRVAASVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 9e-28 41
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 9e-28 41