Gene Information

Name : serS (CCA00897)
Accession : NP_829759.1
Strain : Chlamydophila caviae GPIC
Genome accession: NC_003361
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1037600 - 1038880 bp
Length : 1281 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTGGATATAAAATTAATACGCAAGGCACCCGAAGAATGTGAAATCCGTCTTCGTAAGAAAGATCCCAATATTTCCCT
TCTCCCTATTCTTGATTTGGATAAAGAAGTCCGCAGATTAAAAACCGACTCGGAATCTCTACAATCTCAAAGAAAACTTT
TATCTACACAAATCCATAAAGCTAAAGCTCAAGGTGAAGACGCCTCTAATATGATTAGTGAAGTGGAGAGGATCTCCCAA
GATCTAGAGAAATTAGAAGCTTCACTAGAGGAAAAGAACGCAACTTTACAAGACCTTCTTGTACGCCTTCCTAATTACCC
TGAAGAAGATGTGCCCGTATGTCCTGACAAATCAGGAAATCAGGTAATTAAAAGTGTAGGTGCTTTACCAACATTTTCTT
TTACTCCTAAACATCACGTAGAGCTTAATCAAAAATTACAAATTTTAGATTTTAAACTTCCTGCAAAAACTTCGGGATCT
GGATGGCCTGCCTATAAAAATCAGGGAGTGATGTTAGAATGGGCATTGCTCACTTATTTATTAAATAAGCAACGGGAGCA
TGGCTTTCAATTATGGTTACCCCCCCTTCTTGTAAAACGTGAAATTCTTTTCGGCTCTGGACAAATTCCTAAATTTGACG
GTCAATACTATTGCGTAGAAGATGGAGACCAATCTCTTTACCTGATTCCCACTGCTGAGGTTGTTCTCAACGGATTCCAT
TCTCAAGAAATTTTTAACGAAAAAGATCTCCCTATATATTATGCAGCCTGCACACCCTGTTTCCGCCGAGAAGCAGGCGC
CGCGGGGGCTAACGAACGCGGTCTTGTTCGTGTACATCAGTTCAATAAAGTGGAGATGTTTGCCTTCACCACGCCAGAAC
AAGCGGATCAGGCTTATGAAAAGATGCTCGCTGTTGTTGAAGACATTCTTACGGAATTAAAACTCCCCTACCGTCTCTCT
TTACTCTCTACAGGGGATATGTCCTTCACAGCATCAAAAACTATAGATGCTGAAGTGTGGCTGCCTGGGCAACAATCGTA
TTATGAAGTTTCTTCTATTTCGCAGTGCACAGATTTCCAATCACGCCGTTCAGAAACTCGTTATAAAGATAGCCAAGGGA
AAATGCATTTTATTCATACCCTTAATGGTTCAGGTTTAGCAACACCACGTTTATTCGTTGCTATTTTAGAAAATAATCAA
CAAAAAGACGGCTCTGTAGTTATTCCTGAAGTTCTACGCCCTTACTTAGGAAATCAGGAAGTATTACTACCTCAAGAATG
A

Protein sequence :
MLDIKLIRKAPEECEIRLRKKDPNISLLPILDLDKEVRRLKTDSESLQSQRKLLSTQIHKAKAQGEDASNMISEVERISQ
DLEKLEASLEEKNATLQDLLVRLPNYPEEDVPVCPDKSGNQVIKSVGALPTFSFTPKHHVELNQKLQILDFKLPAKTSGS
GWPAYKNQGVMLEWALLTYLLNKQREHGFQLWLPPLLVKREILFGSGQIPKFDGQYYCVEDGDQSLYLIPTAEVVLNGFH
SQEIFNEKDLPIYYAACTPCFRREAGAAGANERGLVRVHQFNKVEMFAFTTPEQADQAYEKMLAVVEDILTELKLPYRLS
LLSTGDMSFTASKTIDAEVWLPGQQSYYEVSSISQCTDFQSRRSETRYKDSQGKMHFIHTLNGSGLATPRLFVAILENNQ
QKDGSVVIPEVLRPYLGNQEVLLPQE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-77 43