Gene Information

Name : pyk (CCA00675)
Accession : NP_829539.1
Strain : Chlamydophila caviae GPIC
Genome accession: NC_003361
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 771744 - 773189 bp
Length : 1446 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGATCGCAAGAACGAAAATCATTTGTACTATAGGTCCAGCAACAAACACTCCAGAAATGCTTGAGAAGCTTTTAGATGC
GGGTATGAATGTTGCTAGGTTGAATTTTAGTCATGGTACTCATGAAAGTCATGGTGAGACAATTCGTCTTCTTAAGGAAT
TGCGAGAAAAGAAAGGGGCTCCTTTAGCGATTATGTTGGATACCAAGGGTCCAGAAATTCGTTTAGGGAATATTCCCACA
CCAATTCAGGTATCTCGAGGTCAGAAAATTACCTTAGTAGGAAAAGAGGTAGAGGGATCTGCCGAAGGTGGCGTTACCTT
ACATCCTCAATGTGTTTTCCCTTATGTGCGTGAGGGTGTTGATGTCTTGATAGACGATGGTTATATTCAAGCTGTTGTGA
CCTCTGTTGGTGAGGATCATCTAGAATTAGAGTTTATTAACTCTGGAGAATTAAAGTCGCACAAGTCTTTAAGCATAAGA
GAAATTGATTTAGCTCTTCCTTTTATGACGGATAAGGATATCAATGATCTTCAGTTTGGCGTTGCGCAGGGCGTTGATGT
TATTGCTGCTTCTTTTGTCCGTTATGCTGAGGATATCGAAAGTATGCGCAAGTGCTTAGCAGATGCTGGCCGTCCGGATA
TGCCCATTATTGCTAAGATAGAAAATCGTTTGGGAGTAGAGAATTTTTCTCAGATTGCTAAAGCTTCCGATGGGATTATG
ATTGCCCGTGGAGATTTAGGGATTGAGCTTTCTGTTGTTGAGGTCCCTAATTTACAGAAGTTTATGGCAAAGATGTCTCG
TGAAATGGGACGTTTTTGCATTACCGCTACGCAAATGTTAGAATCTATGATTCGCAATGTTTTACCGACACGAGCAGAAG
TTTCTGATGTTGCTAATGCTATTTATGATGGTACCTCAGCAGTAATGTTATCTGGGGAAACGGCCTCGGGAAGTTATCCT
GTCGCGGCTGTGAAAATTATGCGTTCTGTGATTCAAGAGACAGAAAAAAATCTTAATTATAAGTCTTTCTTAGAACTTAG
CGATAGTGAATGTGCTGTTAAGGTATCCCCTTATCTTAAGTCTATAGGTTTATCAGGAATTCAAATTGCTGAGAAAGCTG
ATGCTAAAGCCATTATCGTTTACACGGAATCCGGAGGATCACCCATTTTCCTTTCTAAATACCGTCCGCGTTTTCCAATT
ATTGCTGTTACACCAAATCTATCTGTGTATTACAGGCTTGCTTTAGAGTGGGGAGTCTATCCTATGCTTACGCAAGAGTC
AGACCGTGCAGTATGGAGACATCAAGCTTGTATTTATGGAATCGAAAGAGGAATTTTATCAAATTATGATAAGATTTTAG
TTTTGAGTCGTGGCGCTCAAATGAAAGATACTAATAATCTTACCTTAACAACGGTAAATGATATCATCACAGCATCAGCT
AAATAA

Protein sequence :
MIARTKIICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGETIRLLKELREKKGAPLAIMLDTKGPEIRLGNIPT
PIQVSRGQKITLVGKEVEGSAEGGVTLHPQCVFPYVREGVDVLIDDGYIQAVVTSVGEDHLELEFINSGELKSHKSLSIR
EIDLALPFMTDKDINDLQFGVAQGVDVIAASFVRYAEDIESMRKCLADAGRPDMPIIAKIENRLGVENFSQIAKASDGIM
IARGDLGIELSVVEVPNLQKFMAKMSREMGRFCITATQMLESMIRNVLPTRAEVSDVANAIYDGTSAVMLSGETASGSYP
VAAVKIMRSVIQETEKNLNYKSFLELSDSECAVKVSPYLKSIGLSGIQIAEKADAKAIIVYTESGGSPIFLSKYRPRFPI
IAVTPNLSVYYRLALEWGVYPMLTQESDRAVWRHQACIYGIERGILSNYDKILVLSRGAQMKDTNNLTLTTVNDIITASA
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-63 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-63 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-63 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-62 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk NP_829539.1 pyruvate kinase VFG0479 Protein 8e-64 43