Gene Information

Name : kdsB (CCA00596)
Accession : NP_829460.1
Strain : Chlamydophila caviae GPIC
Genome accession: NC_003361
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 676068 - 676832 bp
Length : 765 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAAAAAGCAAGTATTTGCTAGTAAAAAGGTTGGAGTTCTACCAGCACGATGGGGCAGCGCAAGATTTACTGGGAAGCC
CTTAGCAAGCATTCTCGGAAAATCTTTAATACGAAGGACTTATGAGAATATCAATCAAAGCATCGCATTAGATAAAGTCA
TTGTAGCTACTGATGATCAACGTATTATGGATCATGTTCTAGACTTCGGCGGCGATTGCGTGCTGACAAGTCCTGAATGC
GCTAATGGAACAGAGCGCACAGCAGAAACCATATCTCGTTACTTCCCTGAAGCTGAGATTATAGTAAATATTCAGGGAGA
TGAGCCCTGCTTACAGCACACCGTTGTTGATGCCCTTGTGAGAAAACTAGAAGAATTTCCTGAAATTCAAATAGTTACTC
CAGTGGCTAAAACTACAGATTCTCATGAGATCTTAACAAATCAAAAAGTGAAATGTGTTTTCGATAAAAACGGAAAGGCT
TTATATTTTAGCAGGAGCCCTATTCCACACATCTTAAAAAAAGAGACACCGATTTATCTTCATATTGGCGTATATGCATT
TAGAAGGAATGCCCTATTCAATTACATTGAATCTTCCCCTACACCATTAAGCCAAGCTGAAGATCTGGAGCAACTGCGTA
TACTAGAACACGGTGGATCTATTCATGTGTGTGTCGTGGAAGCTAAGAGCCCCTCAGTTGATTATCCTGAAGATATAAAC
AAGGTGGAAAAATACTTAACATGCCATTCAAGTGCATCTTTTTAA

Protein sequence :
MKKQVFASKKVGVLPARWGSARFTGKPLASILGKSLIRRTYENINQSIALDKVIVATDDQRIMDHVLDFGGDCVLTSPEC
ANGTERTAETISRYFPEAEIIVNIQGDEPCLQHTVVDALVRKLEEFPEIQIVTPVAKTTDSHEILTNQKVKCVFDKNGKA
LYFSRSPIPHILKKETPIYLHIGVYAFRRNALFNYIESSPTPLSQAEDLEQLRILEHGGSIHVCVVEAKSPSVDYPEDIN
KVEKYLTCHSSASF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 3e-34 41
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 2e-34 41