Gene Information

Name : sctN (CCA00035)
Accession : NP_828909.1
Strain : Chlamydophila caviae GPIC
Genome accession: NC_003361
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 43995 - 45323 bp
Length : 1329 bp
Strand : +
Note : similar to GB:Z33880, and PID:535939; identified by sequence similarity

DNA sequence :
ATGGACGAATTGACGACAGATTTTGACACTCTGATGTCGCAATTAAACGACGTGCATTTGACTACCGTTGTAGGTCGTAT
CACTGAAGTTGTCGGTATGTTAATCAAAGCCGTTGTTCCCAATGTTCGTGTTGGGGAAGTGTGCTTGGTTAAACGTCAGG
GTATGGAGCCTCTTGTTACCGAAGTTGTTGGCTTCACACAAAGTTTTGCTTTTCTATCACCATTGGGAGAACTTTCTGGG
GTTAGCCCTTCTTCAGAAGTGATCCCAACTGGTCTCCCTTTGTACATCCGTGCAGGGAATGGTCTTTTAGGGCGTGTGTT
GAATGGTTTGGGAGAACCTATTGATACCGAACTGAAAGGACCCTTAGTCGATGTTAATGAAACCTATCCTGTTTTCCGTG
CTCCACCAGATCCGTTGCATAGGGAAAAGTTAAGAACGATCTTGTCCACAGGCGTGCGCTGCATCGATGGTATGCTCACA
GTAGCTAGAGGTCAGCGTATCGGGATTTTCGCTGGAGCCGGTGTGGGTAAATCCTCCCTTCTAGGGATGATTGCTAGAAA
TGCTGAAGAAGCCGATGTTAACGTGATTGCTCTCATAGGAGAGCGGGGACGTGAGGTTCGCGAGTTTATTGAGGGGGACC
TTGGAGAAGAAGGAATGAAACGATCGGTGATCGTCGTTTCTACATCCGATCAATCATCACAATTACGATTAAATGCTGCT
TATGTGGGTACTGCTATAGCAGAATATTTTCGTGATCAGGGAAAAACTGTCGTTTTAATGATGGATTCTGTAACCCGATT
TGCCCGAGCCTTAAGGGAAGTAGGATTAGCTGCTGGAGAGCCTCCAGCTAGAGCAGGATACACACCTTCAGTATTTTCAA
CGTTACCTAGACTTCTAGAACGTTCGGGAGCATCAGATAAAGGAACAATCACAGCATTTTACACTGTGCTTGTCGCTGGA
GATGATATGAACGAACCTGTTGCCGACGAAGTTAAATCGATTCTTGATGGACATATTGTCTTATCAAATGCTTTAGCACA
GGCATATCACTATCCTGCTATTGATGTTTTGGCATCAATTAGCCGATTGCTAACAGCAATTGTTCCTGAGGAACAAAGAC
GCATCATAGGAAAAGCTCGTGAGGTATTAGCAAAGTATAAAGCAAACGAAATGCTTATACGTATTGGAGAATACCGCCGA
GGTTCTGATCGCGAAGTGGATTTTGCTATAGATCACATAGACAAACTGAATAGATTCTTAAAGCAAGATATCCATGAAAA
AACTAATTACGAGGAAGCTGCGCAACAACTTCGGGCTATTTTCCGATAA

Protein sequence :
MDELTTDFDTLMSQLNDVHLTTVVGRITEVVGMLIKAVVPNVRVGEVCLVKRQGMEPLVTEVVGFTQSFAFLSPLGELSG
VSPSSEVIPTGLPLYIRAGNGLLGRVLNGLGEPIDTELKGPLVDVNETYPVFRAPPDPLHREKLRTILSTGVRCIDGMLT
VARGQRIGIFAGAGVGKSSLLGMIARNAEEADVNVIALIGERGREVREFIEGDLGEEGMKRSVIVVSTSDQSSQLRLNAA
YVGTAIAEYFRDQGKTVVLMMDSVTRFARALREVGLAAGEPPARAGYTPSVFSTLPRLLERSGASDKGTITAFYTVLVAG
DDMNEPVADEVKSILDGHIVLSNALAQAYHYPAIDVLASISRLLTAIVPEEQRRIIGKAREVLAKYKANEMLIRIGEYRR
GSDREVDFAIDHIDKLNRFLKQDIHEKTNYEEAAQQLRAIFR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-104 56
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-77 55
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-77 55
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-93 53
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-93 52
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-93 52
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-94 52
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 6e-93 52
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 3e-94 52
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 3e-94 52
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-93 52
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-94 52
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 3e-81 52
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-79 50
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-79 50
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-79 50
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 5e-79 49
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-79 49
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-73 47
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-76 47
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-76 47
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-80 47
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-80 47
escN CAC81862.1 EscN protein Virulence LEE II Protein 6e-81 47
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-80 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-80 47
escN AAC38383.1 EscN Virulence LEE Protein 3e-80 47
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-80 47
escN AAK26715.1 EscN Virulence LEE Protein 2e-80 47
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-80 47
escN AAL57542.1 EscN Virulence LEE Protein 2e-80 47
escN AAC31513.1 L0034 Virulence LEE Protein 1e-80 47
unnamed AAL06369.1 EscN Virulence LEE Protein 4e-78 47
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-80 47
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 3e-82 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-71 46
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-75 46
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-67 45
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-85 45
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-79 45
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 7e-80 45
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 3e-67 44
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-67 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 4e-71 44
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 4e-71 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-79 44
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 3e-63 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-63 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-63 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-63 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sctN NP_828909.1 type III secretion system ATPase VFG2144 Protein 0.0 93
sctN NP_828909.1 type III secretion system ATPase VFG0192 Protein 4e-109 58
sctN NP_828909.1 type III secretion system ATPase VFG0390 Protein 5e-104 56
sctN NP_828909.1 type III secretion system ATPase VFG0048 Protein 4e-105 55
sctN NP_828909.1 type III secretion system ATPase VFG0515 Protein 1e-79 50
sctN NP_828909.1 type III secretion system ATPase VFG0812 Protein 7e-81 47
sctN NP_828909.1 type III secretion system ATPase VFG0730 Protein 1e-80 47
sctN NP_828909.1 type III secretion system ATPase VFG2459 Protein 2e-68 45
sctN NP_828909.1 type III secretion system ATPase VFG2499 Protein 5e-77 45
sctN NP_828909.1 type III secretion system ATPase VFG2331 Protein 1e-76 44
sctN NP_828909.1 type III secretion system ATPase VFG1254 Protein 2e-78 44
sctN NP_828909.1 type III secretion system ATPase VFG0555 Protein 1e-63 43
sctN NP_828909.1 type III secretion system ATPase VFG1778 Protein 2e-69 43
sctN NP_828909.1 type III secretion system ATPase VFG1008 Protein 3e-61 42