Gene Information

Name : hemC (BMEI0176)
Accession : NP_539094.1
Strain :
Genome accession: NC_003317
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 171214 - 172242 bp
Length : 1029 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGTTCAGCAAAAGTGGAAACCGGTTTTGCCTTTGGACATGCATGAAAACGAATGATGAAACCCGGTACCATGGACGAGG
CAATATGCAAACAGCATCCTTCAAGAATGGCACGTTGAAGATCGGCACCAGGGGCAGCAAGCTGGCTCTGGCACAGGCTT
ACCTCACGCGCCGCCTTTTGCAGGAGGCTCATGGTTTGCCGGAAGATGCGATTGAAATCCTGCCCATGTCCACCGCAGGC
GACCGCATTCAGGACCGCCCGCTTTCGGAAGTTGGCGGCAAGGGGCTGTTTACGGAGGAAATCGAGCAGGCGCTGAAGGA
TGGGCGAATCGATATTGCCGTCCACTCGACCAAGGATATGCCCACCGCCTTGCCAGAGGGGCTTCACCTTTCCGTTTTTC
TGGAGCGTGAGGACCCGCGCGACGCTTTCATCGGGCGCAGCGCAAGGCGTTTCATGGATTTGCCGCAGGGCGCCACCGTT
GGCTCGTCCTCGCTGCGCCGTCAGGCGCTTATTCGCCGTCTTCGCCCGGATATCGAGGTGGTGATGTATCGCGGCAATGT
GGATACCCGCCTGCGCAAGCTCGATGCGGGCGAAGTGGATGGCACTTTCCTTGCCTGTGCCGGTTTGCGCCGGCTCGGCC
TTGCCGATGTCATCACCGATGTTCTCGATCCATCCGTTTTCCCGCCTGCGCCGGGGCAGGGCGCAATCGGCATTGAAAGC
CGCATTGGCGACGAGCGGATCGATGTGCTTCTTGCGCCGCTCGCCCATCGCGAAACGCAAATTGCGCTTGCCTGCGAGCG
GGCCTTTCTCGGCGCTCTCGACGGTTCCTGCCGTACGCCTATTGCCGGTCTTGCAACGGTCGAGGGCGACCGGTTGTCCT
TCCGCGGGATGATCCTGACGCCGGATGGCCGGCAGGCCCATGAAGTGACGGCCGAAGGGGTTGTCTCGGATGCAGCCGCG
CTCGGCACAGATGCGGCAAACCGCGTGCGCGCCATGGCGGGCCCGCATTTCTTTGATGGGTGGCAGTAG

Protein sequence : 
MFSKSGNRFCLWTCMKTNDETRYHGRGNMQTASFKNGTLKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAG
DRIQDRPLSEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTALPEGLHLSVFLEREDPRDAFIGRSARRFMDLPQGATV
GSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVDGTFLACAGLRRLGLADVITDVLDPSVFPPAPGQGAIGIES
RIGDERIDVLLAPLAHRETQIALACERAFLGALDGSCRTPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEGVVSDAAA
LGTDAANRVRAMAGPHFFDGWQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-47 49
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-47 49