Gene Information

Name : thyA (RSc0947)
Accession : NP_519068.1
Strain : Ralstonia solanacearum GMI1000
Genome accession: NC_003295
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 994874 - 995668 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCAGCCCTATCTCGACCTGATGCGCCATGTCCACGAGCATGGCACCGACAAAGCCGACCGCACCGGCACTGGCACGCG
CTCCGTGTTCGGCCATCAGATGCGCTTCGACCTGCAGCAGGGCTTTCCGCTGGTGACCACCAAGAAGGTCCACATCAAGT
CCATCGTCTATGAGCTGCTGTGGTTCCTGCAGGGCGCGACCAACGTGCGCTGGCTGCGGGAGAACGGCGTCACCATCTGG
GACGAATGGGCCGATGCGGAAGGTGAACTGGGCCCGATCTACGGCTACCAGTGGCGCTCGTGGCCGACGCCGTCCGGCGA
GCACATCGACCAGATCGCCGAACTGATCGCGCAGATCAAGCGCAATCCGGACTCGCGCCGGCTGATCGTCTCGGCCTGGA
ACGTGGCCGACATTCCGCGCATGAAGCTGCCGCCCTGCCACGCGTTCTTCCAGTTCTATGTGGCCGACGGCAAGCTGTCG
TGCCAGCTCTACCAGCGCAGCGCGGACATCTTCCTCGGCGTGCCGTTCAACATCGCCAGCTACGCGCTGCTCACGCACAT
GATCGCGCAGCAGACCGGCCTGGACGTGGGCGACTTCGTCTGGACCGGCGGCGACTGCCATCTCTACAACAACCACTTCG
AACAGGTCGAGACGCAACTCGCGCGCACGCCGCTGCCGCTGCCGAAGCTGCACATCAAGCGCAAGCCGGACAGCATCTTC
GATTACCGGTACGAAGACTTCGAGATCGTCGGCTACGAAAGCCATCCCGCGATCAAGGCGCCCGTGGCCGTATGA

Protein sequence :
MQPYLDLMRHVHEHGTDKADRTGTGTRSVFGHQMRFDLQQGFPLVTTKKVHIKSIVYELLWFLQGATNVRWLRENGVTIW
DEWADAEGELGPIYGYQWRSWPTPSGEHIDQIAELIAQIKRNPDSRRLIVSAWNVADIPRMKLPPCHAFFQFYVADGKLS
CQLYQRSADIFLGVPFNIASYALLTHMIAQQTGLDVGDFVWTGGDCHLYNNHFEQVETQLARTPLPLPKLHIKRKPDSIF
DYRYEDFEIVGYESHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 9e-90 66