Gene Information

Name : serS (RSc2337)
Accession : NP_520458.1
Strain : Ralstonia solanacearum GMI1000
Genome accession: NC_003295
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 2534810 - 2536126 bp
Length : 1317 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTCGACATCCAACTGCTCCGCAAAGACATCGACGCCGTCGCCGCGCGCCTGAACGACCGCGGCTACGAACTCGACGT
GGCCGGCTTCGCCGCGCTCGAAGCGGAACGCAAGGCCATCCAGACCCGTACCGAAGAACTGCAGGCGCGCCGCAACAGCC
TGTCCAAGCAGATCGGCATGCTCAAGGGCAAGGGCGAGGACGCCTCGGCGGTGATGGCGGAAGTCGCCGGCATCGGCGAC
GAGCTCAAGGCCTCGGCCGCGCAGCTCGACGTGGTGCAGGGCAGGCTGCAGGACCTGCTGCTGTCGATCCCGAACGTGCC
GCACGAGAGCGTGCCGGCCGGCAAGAGCGAGGCCGAGAACGTCGAGGTGCGTCGCGAAGGCACGCCGCGCGCGTTCGACT
TCCCGGTCAAGGACCATGTCGATCTGGGCGCCGGGCTGGGGCTGGATTTCGACGTGGCCGCCAAGCTGAGCGGTTCGCGC
TTCGCGGTGCTCAAGGGCCCGGTGGCGCGCCTGCATCGCGCGCTCGCGCAGTTCATGCTCGACACCCACACGCAGGAGCA
CGGCTACACCGAGGCCTACGTACCCTACATCGTCAATGCCGCGTCGATGCGCGGCACCGGCCAGTTGCCGAAGTTCGAGG
AAGACCTGTTCCGCGTGCCCCGCAAGATGGGACAGGCCACTGAAGCCGAGGCCGGCGAGCACGTCGAGAATTTCTACCTG
ATCCCGACCGCCGAGGTGCCGCTGACCAACCTCGTGCGCGATGAGATCGTCGCGGGCGATGCGCTGCCGATGAAGTTCGC
CGCGCATTCGCCGTGCTTCCGCTCGGAGGCCGGCTCGTACGGCAAGGACACGCGCGGCATGATCCGCCAGCACCAGTTCG
ACAAGGTCGAGATGGTGCAGATCGTGCAGCCGGAGACGTCGTTCGAGGCGCTGGACGCCATGACGCACCATGCGGAGAAC
ATCCTGCGCAAGCTGGAGTTGCCGTTCCGCACCGTCGTGCTGTGCACCGGCGACATGGGCTTCGGCAGCACCAAGACGTA
CGACATCGAGGTGTGGATCCCCGCGCAGAACACCTATCGCGAGATCAGCTCGTGCTCCAACATGGGCGATTTCCAGGCGC
GCCGCATGCAGGCCCGCTTCCGCAATGCGCAGGGCAAGCCGGAGCTGCTGCACACGCTCAACGGCTCCGGCCTCGCCGTG
GGCCGCACGCTGGTGGCCGTGCTGGAGAACTACCAGAACGCCGATGGTTCGGTGACGGTGCCGGCGGCGCTGCGCCCGTA
CCTGGGCGGCCAAGCGGTGCTGAAACCGGCGGCCTGA

Protein sequence :
MLDIQLLRKDIDAVAARLNDRGYELDVAGFAALEAERKAIQTRTEELQARRNSLSKQIGMLKGKGEDASAVMAEVAGIGD
ELKASAAQLDVVQGRLQDLLLSIPNVPHESVPAGKSEAENVEVRREGTPRAFDFPVKDHVDLGAGLGLDFDVAAKLSGSR
FAVLKGPVARLHRALAQFMLDTHTQEHGYTEAYVPYIVNAASMRGTGQLPKFEEDLFRVPRKMGQATEAEAGEHVENFYL
IPTAEVPLTNLVRDEIVAGDALPMKFAAHSPCFRSEAGSYGKDTRGMIRQHQFDKVEMVQIVQPETSFEALDAMTHHAEN
ILRKLELPFRTVVLCTGDMGFGSTKTYDIEVWIPAQNTYREISSCSNMGDFQARRMQARFRNAQGKPELLHTLNGSGLAV
GRTLVAVLENYQNADGSVTVPAALRPYLGGQAVLKPAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-109 56