Gene Information

Name : lysS (all4071)
Accession : NP_488111.1
Strain : Nostoc sp. PCC 7120
Genome accession: NC_003272
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 4899267 - 4900952 bp
Length : 1686 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCGGAAGAAGATATCCGTGCCGCTAGGCTGGAGAAAGTAGAACAACTCAAGCAGCTAGGGACTAACCCCTATGCTTA
CCGTTGGGAGTCTACTCATCACGCCGCCCAATTGCAAGAAAAATTTGCTGATTTAACCAGTGGTGAAGAAGTCGAGACAG
AAGTTGCCATTGCCGGACGCATTATGGCGCGTCGCGTTTTCGGTAAATTGGCTTTCTTCACCTTGGAGGATGAAACAGGC
ACTATTCAGCTTTATTTAGAGAAAAATCGTATCCAAGAAAGCATGGCAGAAATTGATGCCAATGCTTTTAATCATCTCAA
ACAACTCACCGATGTAGGGGATATTCTGGGAGCCAAGGGAACAATAAAACGGACTGAAAAGGGCGAGTTATCGGTTTACG
TCAAAGAATATACCATCCTCACCAAATCCCTACTGCCGCTACCCGACAAGTGGCATGGGTTAACGGATGTTGCCAAACGC
TACCGTCAACGCTACGTTGATTTGATTGTTAACCCCGAAGTCCGCCAAACTTTCCGCCGTCGCGCCCAAATCACGGCCGG
GATTCGCCGCTATTTGGAACAAAGGGATTTTCTAGAGATTGAAACCCCTGTTTTACAAAGTGAAGCCGGCGGTGCTGATG
CGCGTCCCTTCGTCACTTACCACAACACCTTAGAAATGGAGTTGTATCTACGAATAGCAACAGAACTCCACCTCAAGCGG
TTGATTGTCGGTGGTTTTGAAAAGGTGTTTGAATTGGGGCGAATTTTCCGTAATGAAGGGATTTCCACCAGACACAACCC
TGAATTTACCTCAATTGAAGTTTATCAAGCCTACGCCGACTACAACGATATGATGGCTCTAACAGAAGGTATTATCACCA
CTGTGGCCCAAGATGTACTCGGCACACTGCAAATTACCTACCAAGGCGAAACGGTAGATTTGACACCACCTTGGCGACGG
GTGACAATGCACGATTTAGTAAAAGAATATACAGGATTGGATTTCCATTCTTTCCAAACACTAGAAGAAGCGAAATCAGC
AGGTAAAAATGCTGGGATTCCTGGTGTAGATGAAGCCCAAACTATAGGTAAAATCCTGAATTTAGCATTTGAAGAAAAGG
TAGAAACAAAGTTAATTCAGCCTACCTTTGTAATTGATTATCCTGTGGAAATTTCGCCATTAGCTAAACCTCACCGTTCT
CAACCTGGGTTAGTAGAAAGATTTGAATTATTCATAGTCGGGCGGGAGACTGCGAATAGTTTCTCAGAATTAACAGATCC
CATCGACCAAAGAGAACGCCTAGAAGCCCAAGCAGCCAAAAAAGCCGCCGGTGACTTAGAAGCCCAAGGTGTAGATGAAG
ACTTCTTGACTGCGTTGGAATACGGGATGCCACCTACAGGAGGTTTAGGTATTGGGATTGATCGGTTAGTCATGTTATTA
ACTGATTCTGCCAGTATTCGGGATGTGATTGCTTTCCCTTTACTCAAACCAGAAGGCAGCTTTATTAAGGCATATCGCTA
TGAGCCAACAACTCAAACACTGACTCTTGAATTTGATAGTGGAAGTATTTACGAATATTTCAAAGTACCGCTTACTGTTA
AAGAAGAATTAGACAATGCACCGTCTAAGGGTCAATATTTCCATAAGTTTATTAAAGGGCAATTCAAGTATGAACAATTG
AGTTGA

Protein sequence :
MSEEDIRAARLEKVEQLKQLGTNPYAYRWESTHHAAQLQEKFADLTSGEEVETEVAIAGRIMARRVFGKLAFFTLEDETG
TIQLYLEKNRIQESMAEIDANAFNHLKQLTDVGDILGAKGTIKRTEKGELSVYVKEYTILTKSLLPLPDKWHGLTDVAKR
YRQRYVDLIVNPEVRQTFRRRAQITAGIRRYLEQRDFLEIETPVLQSEAGGADARPFVTYHNTLEMELYLRIATELHLKR
LIVGGFEKVFELGRIFRNEGISTRHNPEFTSIEVYQAYADYNDMMALTEGIITTVAQDVLGTLQITYQGETVDLTPPWRR
VTMHDLVKEYTGLDFHSFQTLEEAKSAGKNAGIPGVDEAQTIGKILNLAFEEKVETKLIQPTFVIDYPVEISPLAKPHRS
QPGLVERFELFIVGRETANSFSELTDPIDQRERLEAQAAKKAAGDLEAQGVDEDFLTALEYGMPPTGGLGIGIDRLVMLL
TDSASIRDVIAFPLLKPEGSFIKAYRYEPTTQTLTLEFDSGSIYEYFKVPLTVKEELDNAPSKGQYFHKFIKGQFKYEQL
S

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 8e-108 48
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 4e-84 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS NP_488111.1 lysyl-tRNA synthetase VFG1668 Protein 5e-108 48