Gene Information

Name : leuS (alr3283)
Accession : NP_487323.1
Strain : Nostoc sp. PCC 7120
Genome accession: NC_003272
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 3956864 - 3959482 bp
Length : 2619 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGGACTCCCGATACAACCCCGCAACACTTGAGGAAAAATGGCAAAAAACATGGGTAGAACTTGGTTTAGATAAGACCCA
AACACAAAGCAACAAACCAAAATTCTACGCTCTATCCATGTTTCCCTATCCATCGGGCAGCCTACACATGGGTCACGTCC
GTAATTACACAATTACAGATGTGATTGCCCGCCTCAAACGAATGCAAGGGTATCGGGTACTGCATCCAATGGGATGGGAT
GCCTTTGGCTTACCAGCAGAAAACGCCGCCATTGACCGTGGTGTACCCCCTGCCAAATGGACTTATCAAAACATTACCCA
AATGCGGCAACAATTGCAGCGTCTTGGTTTATCCATTGACTGGGATAGCGAAGTTGCCACCTGTTCGCCAGATTATTACA
AATGGACACAGTGGATTTTCTTACAGTTCTTACAGGCGGGGTTAGCTTACCAAAAAGAAGCAGCCGTCAACTGGGACCCC
ATTGACCAAACTGTATTAGCAAACGAACAAGTTGATAACGAAGGTCGTTCTTGGCGTAGCGGCGCTATTGTTGAGCGTAA
ATTACTCAGGCAGTGGTTTTTGAAGATTACCGACTACGCCGAAGAATTATTAAATGACCTAGATAAATTGACTGGTTGGC
CAGAACGTGTCAAATTGATGCAGGCGAACTGGATAGGGAAATCCTCAGGAGCCTATTTAGAATTTCCCATTGTCGGCAGC
AATGAAAAAATAGCTGTGTATACTACCCGCCCTGATACAGTTTACGGGGTCAGCTATGTAGTATTGGCACCAGAACATCC
CCTCACCAAGCAAGTTACAACCAAAACACAACAAGCAGCAGTAGACACCTTTATTCAAGAGGTGACAAATCAAAGCGAAT
TGGAACGTACCGCCGAAGACAAACCTAAACGAGGTATAGCCACTGGTGGTAAGGCAATTAACCCGTTTACAGGGGAAGAA
GTACCCATTTGGATTGCCGACTATGTACTGTATGAGTATGGTACTGGGGCTGTAATGGGTGTACCTGCCCACGATGTACG
GGATTTTAAATTTGCTCAGAGATATGACTTACCCATTGATTTTGTCATTGCGGCCCCTGATGATGTAGCAGGTTTTGACT
TAAGCCCGACATCAGAGACAGAAGAAGTCACTCAAGTCGTGCAGATAGAATATAACCAAGCCTACACAGAACCAGGAATC
TTAATTAATTCTGGGGCTTTTACTGGTATGACTTCCACAGATGCCAAACAGGCGATTGTGAAATATGCCACAGAAAAAGG
TTTTGGCAAAGAACGTATTCAATATCGCTTGCGGGACTGGTTGATTTCTCGGCAACGCTATTGGGGCGCACCAATTCCCG
TCATTCATTGCCCCAATTGTGGGATAGTACCAGTACCTGACAAAGATTTGCCCGTCATTTTACCAGAAGAAGTGGAATTT
ACTGGACGAGGTGGTTCACCGTTGGCACAGTTGGAAAGCTGGGTAAATGTCCCTTGTCCTACCTGTGGTACTCCTGCCAA
ACGGGAAACCGATACGATGGACACCTTCATTGATTCCTCGTGGTATTTCTTGCGGTTTACTGATGCTAGGAACGAAGCAC
AGGTATTTGAATCAGCAAAAACCAATGACTGGATGCCCGTAGACCAATATGTAGGCGGTATTGAACACGCAATTTTGCAC
TTGTTATATTCCCGCTTCTTCACGAAAGTATTGCGCGATCGCGGCTTGTTGAATTTTGATGAACCTTTTGAGCGTTTGTT
AACTCAAGGGATGGTACAAGGTTTAACTTACTTCAATCCGAACAAGGGTGGTAAAGATAAGTGGGTTCCTTCCCATTTAG
TTAACCCCAATGACCCTCGTGACCCCCAAACAGGCGAACCACTGCAACGGCTTTACGCCACCATGTCCAAATCTAAAGGC
AACGGTGTCGCACCGGAAGATGTGATTGCTAAATATGGTGTAGATACGGCGCGGATGTTCATCTTATTTAAAGCGCCGCC
AGAAAAAGATTTGGAATGGGATGAAGCTGATGTAGAAGGACAATTCCGCTTTTTAAATCGGGTTTGGCGTTTGGTGACAG
ATTATGTAGCATCTGGGGTAAACCCTAAAAATAAATCTGGCGAATTGAGCAAGTCAGAAAAAGACTTACGGCGGGCAATT
CACACTGCTATTCAGTCGGTGACGGAAGATTTAGAGGATGATTATCAGTTTAATACTGCTATTTCCGAATTGATGAAGTT
AAGTAACGCCCTTACTGATGCTAACGGCAAAGATTCACGGGTTTATGCTGAGGGTATTAAGACATTGGTGGTTTTGCTGG
CTCCTTTTGCACCACACATTGCTGAGGAATTGTGGCGATTATTGGGTAATAGCGAGTCAGTGCATACTCAAACCTGGCCT
GCTTTTGACCCAGCTGCTTTGGTTGCCGATGAAATCACTTTAGTGATTCAAGTTAATGGTAAGAAGCGTGCTGACATTCA
AGTTCCGTCACAAGCTGATAAAGCTGAGTTAGAGAAATACGCCCGCGAATCAGAAGTTGTGCAACGTCACCTTGAAGGCA
AGGAAATTAAAAAGGTAATTGTCGTGCCTGGAAAGTTAGTTAATTTTGTCGTTGGTTAA

Protein sequence :
MDSRYNPATLEEKWQKTWVELGLDKTQTQSNKPKFYALSMFPYPSGSLHMGHVRNYTITDVIARLKRMQGYRVLHPMGWD
AFGLPAENAAIDRGVPPAKWTYQNITQMRQQLQRLGLSIDWDSEVATCSPDYYKWTQWIFLQFLQAGLAYQKEAAVNWDP
IDQTVLANEQVDNEGRSWRSGAIVERKLLRQWFLKITDYAEELLNDLDKLTGWPERVKLMQANWIGKSSGAYLEFPIVGS
NEKIAVYTTRPDTVYGVSYVVLAPEHPLTKQVTTKTQQAAVDTFIQEVTNQSELERTAEDKPKRGIATGGKAINPFTGEE
VPIWIADYVLYEYGTGAVMGVPAHDVRDFKFAQRYDLPIDFVIAAPDDVAGFDLSPTSETEEVTQVVQIEYNQAYTEPGI
LINSGAFTGMTSTDAKQAIVKYATEKGFGKERIQYRLRDWLISRQRYWGAPIPVIHCPNCGIVPVPDKDLPVILPEEVEF
TGRGGSPLAQLESWVNVPCPTCGTPAKRETDTMDTFIDSSWYFLRFTDARNEAQVFESAKTNDWMPVDQYVGGIEHAILH
LLYSRFFTKVLRDRGLLNFDEPFERLLTQGMVQGLTYFNPNKGGKDKWVPSHLVNPNDPRDPQTGEPLQRLYATMSKSKG
NGVAPEDVIAKYGVDTARMFILFKAPPEKDLEWDEADVEGQFRFLNRVWRLVTDYVASGVNPKNKSGELSKSEKDLRRAI
HTAIQSVTEDLEDDYQFNTAISELMKLSNALTDANGKDSRVYAEGIKTLVVLLAPFAPHIAEELWRLLGNSESVHTQTWP
AFDPAALVADEITLVIQVNGKKRADIQVPSQADKAELEKYARESEVVQRHLEGKEIKKVIVVPGKLVNFVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 6e-170 44