Gene Information

Name : hemC (alr1878)
Accession : NP_485918.1
Strain : Nostoc sp. PCC 7120
Genome accession: NC_003272
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2240586 - 2241596 bp
Length : 1011 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAGAGTGAAATTATCGCCTGGTTTGACATATTGTTTTATGACTTCAGTTGTTTCCAGTGCTAGACGCACAATCCGTAT
AGGTTCTCGTAAAAGTCAACTCGCTCTAGTTCAGACATACTGGGTTAGAGAGCAATTACAAAACAGTTTCCCTGATATCA
ATTTTGAAGTCCACACCATGTCTACCCAAGGCGACAAAATCCTTGATGTAGCATTAGCCAAAATCGGCGATAAAGGACTA
TTCACCAAAGAACTGGAAGTGGGAATGATCAATGAGGAGATTGATTTTGCTGTCCATTCCCTGAAAGATTTGCCGACTAA
CTTACCGGAAGGGTTAGCACTAGCCGCGATTACAGAACGGGAAAACCCGGCAGATGCGCTAGTAGTGCATGAAAATTTTA
AGGATAAGCAAATTGATACCTTACCAGCCGGCGCGGTAATTGGGACATCTTCTTTACGACGCTTGGCGCAGTTACGCAAC
CAATTTCCCCACTTGACATTTAAAGATGTACGGGGAAATTTGAATACACGGTTAGCTAAACTAGATGCAGGTGAGTATGA
CGGTCTAATTTTAGCGGCTGCTGGGTTACAGCGCTTAGGTATGGGCGATCGCGTCCACCAAATCCTCCCCAAAGAAATCT
CTCTCCACGCTGTCGGACAAGGCGCTTTAGGGATTGAATGCCGTGCCGATGATGCGGAATTAATCACCGTACTCAAAGCC
ATTGAACACCCCGAAACACGCGATCGCTGTCTGGCTGAACGCTCTTTTTTACGCAGTTTAGAAGGCGGTTGTCAAGTACC
CATCGGTGTAAATACAGAAATCAATGGTAATGAATTAATCCTCACAGGTGTAGTTGCTAGTGTAGACGGTCAAAACTTGG
TGAAAGACACTGTTTCTGGTAATGCTAGTGATGCCGAAGCGATCGGTATAAGATTAGCAGAACTCCTCCGTGAACAAGGA
GCGCAAGAGATTTTAAATACAATCTTTGCAGAGATCCAACGTGGTTCTTAA

Protein sequence :
MRVKLSPGLTYCFMTSVVSSARRTIRIGSRKSQLALVQTYWVREQLQNSFPDINFEVHTMSTQGDKILDVALAKIGDKGL
FTKELEVGMINEEIDFAVHSLKDLPTNLPEGLALAAITERENPADALVVHENFKDKQIDTLPAGAVIGTSSLRRLAQLRN
QFPHLTFKDVRGNLNTRLAKLDAGEYDGLILAAAGLQRLGMGDRVHQILPKEISLHAVGQGALGIECRADDAELITVLKA
IEHPETRDRCLAERSFLRSLEGGCQVPIGVNTEINGNELILTGVVASVDGQNLVKDTVSGNASDAEAIGIRLAELLREQG
AQEILNTIFAEIQRGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-64 50
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-64 50