Gene Information

Name : guaA (BF0887)
Accession : YP_210582.1
Strain : Bacteroides fragilis NCTC 9343
Genome accession: NC_003228
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1107698 - 1109221 bp
Length : 1524 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCAAGAGAAAATTATAATACTTGATTTCGGTTCACAGACCACGCAGCTTATCGGTCGCCGGGTGCGCGAGTTGGATAC
GTATTGCGAGATTGTCCCCTATAACAAGTTCCCCAAAGGCGATGAAACCGTCAAGGGAGTGATTCTGTCGGGAAGCCCCT
TCTCCGTATATGACGAAAGTGCGTTCAAGGTCGATTTGAGCGAAATCAGAGGTAAATACCCCATCTTGGGCATCTGCTAT
GGTGCACAGTTTATGGCGTATACCAATGGTGGCAAAGTAGAACCGGCAGGTACCCGTGAGTATGGACGTGCTCACCTGAC
TTCTTTCTGCAAGGACAATGTTTTGTTCAAAGGTGTGAGAGAGGGTACGCAGGTATGGATGAGCCACGGTGATACCATTA
CTGCTATCCCTGAGAATTTTAAAACCATTGCATCGACAGACAAAGTGGCTATTGCCGCCTATCAGGTAGAGGGCGAACAG
GTATGGGGAGTACAGTTCCATCCGGAAGTTTTCCACAGTGAAGACGGTACGCAGATGCTTCGCAATTTCGTTGTCGATGT
ATGTGGCTGTAAACAGGACTGGAGTCCGGCGTCATTCATCGAGAGCACGGTTGCCGAATTGAAAGCTCAGCTGGGTGATG
ACAAGGTTGTACTGGGATTAAGCGGAGGAGTTGACTCTTCTGTAGCCGCCGTTTTGCTGAACAGGGCTATTGGCAAGAAT
CTGACTTGTATTTTCGTTGACCACGGTATGCTTCGCAAGAACGAGTTTAAGAACGTGATGCACGATTACGAATGCCTTGG
CTTGAACGTGATTGGTGTGGATGCCAGTGAGAAGTTCTTCTCTGAACTGGAAGGCGTCACCGAACCTGAACGTAAACGTA
AAATTATAGGTAAAGGATTTATTGACGTATTCGATGAAGAAGCACATAAACTGAAAGATGTGAAATGGCTGGCTCAGGGT
ACGATTTATCCGGACTGTATCGAGTCGCTTTCTATCACCGGTACTGTTATCAAGAGTCACCACAATGTGGGAGGACTTCC
TGAAAAGATGAATCTAAAACTTTGTGAACCGCTTCGCCTGTTGTTTAAGGACGAGGTTCGTCGTGTAGGTAGAGAGTTAG
GTATGCCCGAGCACTTGATTACCCGTCATCCTTTCCCCGGGCCGGGACTTGCTGTTCGTATCTTAGGTGATATTACTCCT
GAGAAGGTTCGTATCTTGCAAGATGCCGATGATATCTTTATTCAGGGTTTGCGCGATTGGGGATTGTACGATCAGGTGTG
GCAGGCAGGTGTTATCTTGCTTCCTGTTCAATCGGTAGGCGTAATGGGAGACGAACGTACTTACGAACGTGCCGTTGCTT
TGCGTGCCGTGACTTCAACGGATGCTATGACAGCCGACTGGGCGCATTTGCCTTATGAATTCCTTGGTAAAGTGTCGAAT
GATATTATAAATAAGGTAAAAGGTGTGAACCGTGTGACCTATGATATCAGTTCGAAGCCACCTGCAACTATCGAATGGGA
ATAA

Protein sequence :
MQEKIIILDFGSQTTQLIGRRVRELDTYCEIVPYNKFPKGDETVKGVILSGSPFSVYDESAFKVDLSEIRGKYPILGICY
GAQFMAYTNGGKVEPAGTREYGRAHLTSFCKDNVLFKGVREGTQVWMSHGDTITAIPENFKTIASTDKVAIAAYQVEGEQ
VWGVQFHPEVFHSEDGTQMLRNFVVDVCGCKQDWSPASFIESTVAELKAQLGDDKVVLGLSGGVDSSVAAVLLNRAIGKN
LTCIFVDHGMLRKNEFKNVMHDYECLGLNVIGVDASEKFFSELEGVTEPERKRKIIGKGFIDVFDEEAHKLKDVKWLAQG
TIYPDCIESLSITGTVIKSHHNVGGLPEKMNLKLCEPLRLLFKDEVRRVGRELGMPEHLITRHPFPGPGLAVRILGDITP
EKVRILQDADDIFIQGLRDWGLYDQVWQAGVILLPVQSVGVMGDERTYERAVALRAVTSTDAMTADWAHLPYEFLGKVSN
DIINKVKGVNRVTYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-123 52
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-123 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-123 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-113 47