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Name : leuS (BF4372) Accession : YP_213927.1 Strain : Bacteroides fragilis NCTC 9343 Genome accession: NC_003228 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 5198827 - 5201658 bp Length : 2832 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGGAATATAATTTCAGGGAGATCGAAAAGAAATGGCAGAAAATTTGGGTAGACAACCATACCTACCAGGTAAATGAAGA TGCATCCAAACAAAAATTCTATGTACTCAATATGTTCCCCTATCCTTCGGGTGCCGGACTGCACGTAGGTCATCCCCTGG GATATATTGCCTCAGACATTTATGCGCGCTATAAACGCCTGCAAGGATTTAACGTATTGAACCCGATGGGATATGATGCT TACGGACTGCCGGCCGAACAATATGCTATTCAAACCGGACAGCACCCTGCAATTACCACTGTTAATAACATCAACCGCTA TCGTGAACAATTAGATAAGATTGGTTTCTCTTTCGACTGGAATCGTGAAATTCGCACTTGCGATCCGGAATATTATCATT GGACCCAATGGGCATTTATCAAAATGTTCAACAGCTATTATTGCAATGATGAAAAACAGGCACGTCCCATCGAAGAGTTA ATAGAAGCTTTTAGTACCAACGGAACACAAGGTATGAACGTAGCCTGTGGCGAAGAAATGGACTTCACTGCCGACGAATG GAATGCTAAAAGCGAAAAAGAACAACAGGAAATCCTCATGAACTACCGTATAGCCTATTTGGGCAATACAATGGTAAACT GGTGTCCGGCTTTGGGTACCGTACTTGCCAATGATGAAGTAGTTGACGGTGTTTCCGAAAGAGGCGGTTATCCCGTTATT CAAAAAGTGATGCGTCAGTGGTGCCTGCGCGTATCCGCTTATGCACAGCGTTTGCTCGACGGACTTGAAACCGTAGAATG GACCGACTCGCTGAAAGAGACTCAACGCAACTGGATAGGACGCAGCGAAGGTGCTGAAATGAACTTTAAAGTGAAAGATT CGGATATTGAATTTACTATCTTTACAACCCGTGCCGACACGGTATTTGGAGTTACTTTCATGGTGCTTGCCCCGGAAAGT GAATTGGTAGCCAAGTTGACCACTCCGGAACAAAAAGCCGAAGTAGATGCTTATCTGGACCGTACCAAAAAACGTACCGA ACGCGAACGTATTGCCGACCGTAGCGTAAGCGGCGTATTCTCCGGAAGCTATGCCATTAACCCATTGACCAACGAACCCA TACCGGTATGGATTAGCGATTATGTATTAGCAGGTTACGGTACAGGTGCCATCATGGCTGTTCCTGCACACGATAGCCGT GACTATGCTTTTGCCAAACATTTCAATCTGGAAATCCGTCCGCTGATCGAAGGTTGCGACGTCAGTGAAGAAAGCTTCGA CGCCAAAGAAGGCATCATGATGAATTCTCCCCGTCCGGGAGCTCCCGAAGGTGGACTCGTATTGAACGGATTGACCGTAA AAGAAGCAATCGCCAAAACTAAAGAATATATCAAGGCAACCGGATTAGGCCGTGTGAAAGTCAATTTCCGTCTGCGTGAT GCAATTTTCTCACGTCAGCGCTATTGGGGCGAACCATTCCCGGTTTACTACAAAGACGGAATGCCTTACATGATTGATGA AAGTTGCCTCCCGCTGGAATTGCCGGAAGTAGCCAAATTCCTTCCTACCGAAACCGGTGAACCACCATTGGGACATGCCA CTAAATGGGCATGGGACACTGTCAACAAATGCGTGACAGACAATGAAAACATTGATAATATAACCATTTTCCCACTGGAA CTGAATACGATGCCGGGATTTGCCGGTTCATCCGCCTATTATCTGCGCTATATGGATCCGCGCAATCACGAAGCTCTCGT TTCTCCCGCCGTGGATCAGTACTGGAAAAATGTAGACTTATATGTAGGAGGTACGGAACATGCTACCGGACACTTGATTT ATTCACGTTTCTGGAATAAGTTCCTGCACGATTGGGGTATCTCCGTAGCCGAAGAGCCTTTCCAGAAACTTGTAAATCAG GGAATGATACAAGGACGAAGTAACTTTGTCTACCGTATCAAGGATACCAATACTTTCGTATCTCTCAATCTGAAAGATCA ATATGAAGTTACTCCTATCCACGTAGATGTCAACATCGTATCCAACGATATCCTCGACCTGGAAGCTTTCAAGGCTTGGA GACCCGAATACGAAACTGCCGAATTTATTCTGGAAGACGGCAAGTATATCTGTGGATGGGCTGTTGAAAAGATGAGTAAA TCTATGTTCAATGTGGTAAATCCGGATATGATTGTTGAAAAATACGGTGCCGATACACTCCGTATGTACGAAATGTTCCT CGGACCGGTTGAACAGTCCAAACCTTGGGATACGAACGGAATAGATGGCGTACATCGTTTCATCAAAAAATTCTGGTCAT TGTTCTATGACAGAAACGGCGAATATCTGGTAAAAGACGAACCGGCTACCAAAGAAGAACTAAAAGCACTCCATAAGTTG ATTAAGAAAGTAACCGGTGATATCGAACAGTTCTCTTACAACACTTCAGTAAGTGCTTTCATGATCTGTGTCAATGAACT TTCAAGTCTGAAATGCAATAAAAAAGAGGTATTGGAGCAACTCATCGTAGTTCTTGCACCTTTTGCTCCGCATGTATGCG AAGAGTTATGGGATACACTGGGAAGCACCACCTCTGTATGTGATGCACAATGGCCGGCTTTCAACGAGCAATACCTGGTA GAAGATACGGTTAATTACACCATTTCTTTCAATGGTAAAGCACGTTTCAATATGGAATTTCCGGCTAATGCCGCCAGCGA CGCGATTCAAGCCACTGTACTTGCCGACGAACGCTCGTTAAAATGGACAGAAGGCAAAACACCGAAGAAAGTTATCGTAG TCCCGAAGAAGATTGTTAACATTGTTATTTAA Protein sequence : MEYNFREIEKKWQKIWVDNHTYQVNEDASKQKFYVLNMFPYPSGAGLHVGHPLGYIASDIYARYKRLQGFNVLNPMGYDA YGLPAEQYAIQTGQHPAITTVNNINRYREQLDKIGFSFDWNREIRTCDPEYYHWTQWAFIKMFNSYYCNDEKQARPIEEL IEAFSTNGTQGMNVACGEEMDFTADEWNAKSEKEQQEILMNYRIAYLGNTMVNWCPALGTVLANDEVVDGVSERGGYPVI QKVMRQWCLRVSAYAQRLLDGLETVEWTDSLKETQRNWIGRSEGAEMNFKVKDSDIEFTIFTTRADTVFGVTFMVLAPES ELVAKLTTPEQKAEVDAYLDRTKKRTERERIADRSVSGVFSGSYAINPLTNEPIPVWISDYVLAGYGTGAIMAVPAHDSR DYAFAKHFNLEIRPLIEGCDVSEESFDAKEGIMMNSPRPGAPEGGLVLNGLTVKEAIAKTKEYIKATGLGRVKVNFRLRD AIFSRQRYWGEPFPVYYKDGMPYMIDESCLPLELPEVAKFLPTETGEPPLGHATKWAWDTVNKCVTDNENIDNITIFPLE LNTMPGFAGSSAYYLRYMDPRNHEALVSPAVDQYWKNVDLYVGGTEHATGHLIYSRFWNKFLHDWGISVAEEPFQKLVNQ GMIQGRSNFVYRIKDTNTFVSLNLKDQYEVTPIHVDVNIVSNDILDLEAFKAWRPEYETAEFILEDGKYICGWAVEKMSK SMFNVVNPDMIVEKYGADTLRMYEMFLGPVEQSKPWDTNGIDGVHRFIKKFWSLFYDRNGEYLVKDEPATKEELKALHKL IKKVTGDIEQFSYNTSVSAFMICVNELSSLKCNKKEVLEQLIVVLAPFAPHVCEELWDTLGSTTSVCDAQWPAFNEQYLV EDTVNYTISFNGKARFNMEFPANAASDAIQATVLADERSLKWTEGKTPKKVIVVPKKIVNIVI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 5e-127 | 42 |
