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Name : clpB (BF2492) Accession : YP_212116.1 Strain : Bacteroides fragilis NCTC 9343 Genome accession: NC_003228 Putative virulence/resistance : Virulence Product : negative regulator of genetic competence Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 2896396 - 2898930 bp Length : 2535 bp Strand : - Note : Similar to Bacillus subtilis negative regulator of genetic competence ClpC/MecB ClpC or MecB SWALL:CLPC_BACSU (SWALL:P37571) (810 aa) fasta scores: E(): 5.8e-119, 48.21% id in 842 aa, and to Bacteroides thetaiotaomicron ATP-dependent Clp protease BT0898 S DNA sequence : ATGAATAATCAATTCTCACAAAAAGTTTCCGATATTATCGTATATAGCAAAGAAGAGGCAAATCGCCTGAAAAGTAGCTA TATAGGGCCTGAGCATTTATTGCTTGGTATGCTTCGCGATGGTGAGGGAAAAGCAATCGAGATATTGTCTAAACTCAAAA CAAACCTGACCGACATAAAGAAGCAGATTGAGGCCATACTGAAAGAGCATGCAGACGACATGCTGTTGCCTGATGCCGAT GTTCCATTGTCAAATGGAGCTGCAAAGATATTGAAACTATGTATTTTAGAAGCACGAGTGATGAAAAGTCAAGTTGCAGA TACGGAACATGTACTGCTGGCCATCCTTAAAGATAAGGATAATCTGGCAGCAACGGTTCTTGAAGCGAATCATGTGAATT ACCAGCAGGTATTCGAACAATTGTCCTTACAGCCGGATATCAGTGCCGGCATGGGATTTACAGAAGATGATGATGACGAA GAAGAGATGAATCAATCCCGTTCGTCCCATGGATCCGGTGAACGTCAGCAACAGGCGCAGACTGCCTCCAGGAAGCCGAC TAATGATACTCCGGTGCTTGATAATTTTGGTACTGATATGACTAAGGCCGCCGAGGAAGGCCGTCTTGACCCTGTGGTGG GACGTGAGCGGGAAATCGAGCGCCTGGCACAGATATTAAGTCGCCGTAAGAAGAATAACCCCATTTTGATCGGTGAACCG GGAGTCGGAAAATCGGCCATAGTGGAAGGTCTGGCACTTCGTATTATACAGAAAAAGGTGTCCCGTATTCTGTTTGATAA GCGTGTGGTTGCACTCGATATGACTGCGGTTGTTGCCGGTACCAAGTACCGCGGACAATTTGAGGAACGCATTCGTTCCA TCTTGAACGAATTGCAGAAGAATCCGAATGTGATTCTGTTCATTGACGAGATACATACCATTGTAGGTGCCGGATCGGCA GCCGGATCAATGGATGCTGCCAACATGTTGAAACCGGCATTGGCACGTGGAGAGATTCAGTGTATCGGTGCCACTACCCT TGACGAATATCGGAAGAATATCGAAAAAGACGGGGCGTTGGAGCGTCGTTTCCAGAAGGTAATGGTAGAGCCTACTACAG CTGACGAAACGTTGCAGATTCTTCGTAATATTAAGGATAAATATGAAGATCATCACAACGTAAATTATACGGATGCGGCA TTGGAAGCTTGTGTCAAGTTGACAGACCGTTATATAACCGACCGTAACTTCCCGGATAAAGCTATTGATGCACTCGATGA AGCCGGTTCGCGTGTACATCTTACCAATGTGAGTGTACCCAAGGAAATAGAAGATCAGGAGAAGTTGATCGAAGAAGCTA AAAATAACAAGAACGAGGCTGTCAAATCACAGAATTTCGAACTTGCTGCCAGTTTTCGCGATAAGGAAAAAGAACTTGCT GTCCAGTTGGATGTGATGAAGAAAGACTGGGAGGAACGTTTGAAGGATAATCGTGAGACGGTGGATGAGGAAGAAATCGC AAATGTCGTATCAATGATGTCCGGCATTCCGGTACAGCGTATGGCACAGGCGGAAGGCATCAAGTTGGCAGGCATGAAAG AAGACCTGCAATCGAAGGTGATAGCTCAGGACGATGCTATCAAAAAGCTGGTCAAGGCCATTCTGCGCAGCCGTGTCGGA CTGAAAGATCCGAATAAACCGATTGGTACATTTATGTTCCTAGGCCCTACCGGTGTTGGTAAAACTCATCTGGCCAAGGA ATTGGCTAAATATATGTTTGGCTCTTCGGATGCATTGATCCGTATCGATATGAGTGAGTTTATGGAGAAATTCACAGTCT CACGCTTGGTTGGAGCGCCTCCGGGATACGTAGGATACGAGGAAGGCGGACAATTGACAGAGAAAGTACGCCGTAAACCC TATTCTATCGTATTGCTTGACGAAATAGAAAAGGCGCATCCCGATGTGTTCAATCTGCTTCTCCAGGTGATGGACGAAGG TCGGCTGACTGACAGTTATGGCAGAATGGTTGACTTCAAGAATACTGTTATTATCATGACATCGAATATCGGAACCCGCC AGTTGAAAGAGTTTGGGCGTGGAGTCGGTTTTGCCACTCAAAGCCGTCTTGACGATAAAGAATTCTCTCGCAGCGTGATT CAGAAGGCTCTGAATAAATCGTTTGCACCCGAATTTATAAATCGTGTTGACGAAATCATCACCTTTGACCAGTTGTCATT AGAAGCTATAACGAAGATTATCGATATTGAGTTGAAAGGACTGTATAACAGAATCGAATCTATCGGCTATAAACTGGTCA TTGAAGACAAGGCTAAACAGTTTGTCGCTTCAAAAGGCTATGATGTCCAGTACGGTGCACGTCCGCTGAAGCGTGCCATC CAGACCTATCTGGAAGACGGCTTATCGGAACTTATCATTTCGGCTGATCTGAATGAAGGAGATACGATCACTGTCTCTTT AAATGAAGAAAAGGGTGAGTTGGAAATGAAGAATGAAGCCAAAACGGCTGAATAA Protein sequence : MNNQFSQKVSDIIVYSKEEANRLKSSYIGPEHLLLGMLRDGEGKAIEILSKLKTNLTDIKKQIEAILKEHADDMLLPDAD VPLSNGAAKILKLCILEARVMKSQVADTEHVLLAILKDKDNLAATVLEANHVNYQQVFEQLSLQPDISAGMGFTEDDDDE EEMNQSRSSHGSGERQQQAQTASRKPTNDTPVLDNFGTDMTKAAEEGRLDPVVGREREIERLAQILSRRKKNNPILIGEP GVGKSAIVEGLALRIIQKKVSRILFDKRVVALDMTAVVAGTKYRGQFEERIRSILNELQKNPNVILFIDEIHTIVGAGSA AGSMDAANMLKPALARGEIQCIGATTLDEYRKNIEKDGALERRFQKVMVEPTTADETLQILRNIKDKYEDHHNVNYTDAA LEACVKLTDRYITDRNFPDKAIDALDEAGSRVHLTNVSVPKEIEDQEKLIEEAKNNKNEAVKSQNFELAASFRDKEKELA VQLDVMKKDWEERLKDNRETVDEEEIANVVSMMSGIPVQRMAQAEGIKLAGMKEDLQSKVIAQDDAIKKLVKAILRSRVG LKDPNKPIGTFMFLGPTGVGKTHLAKELAKYMFGSSDALIRIDMSEFMEKFTVSRLVGAPPGYVGYEEGGQLTEKVRRKP YSIVLLDEIEKAHPDVFNLLLQVMDEGRLTDSYGRMVDFKNTVIIMTSNIGTRQLKEFGRGVGFATQSRLDDKEFSRSVI QKALNKSFAPEFINRVDEIITFDQLSLEAITKIIDIELKGLYNRIESIGYKLVIEDKAKQFVASKGYDVQYGARPLKRAI QTYLEDGLSELIISADLNEGDTITVSLNEEKGELEMKNEAKTAE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| clpC | YP_005163377.1 | ATP-dependent Clp protease ATP-binding subunit | Not tested | Not named | Protein | 0.0 | 46 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| clpB | YP_212116.1 | negative regulator of genetic competence | VFG0080 | Protein | 3e-148 | 49 |
| clpB | YP_212116.1 | negative regulator of genetic competence | VFG0079 | Protein | 0.0 | 48 |
