Gene Information

Name : wcfS (BF1377)
Accession : YP_211035.1
Strain : Bacteroides fragilis NCTC 9343
Genome accession: NC_003228
Putative virulence/resistance : Virulence
Product : undecaprenyl-phosphate galactose phosphotransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG2148
EC number : -
Position : 1645005 - 1645592 bp
Length : 588 bp
Strand : +
Note : Similar to previously sequenced Bacteroides fragilis undecaprenyl-phosphate galactose phosphotransferase WcfS SWALL:Q93QV6 (EMBL:AF189282) (198 aa) fasta scores: E(): 4.8e-76, 99.48% id in 195 aa, and to Bacteroides thetaiotaomicron glycosyltransferase BT

DNA sequence : 
TTGATCCGTTTTTTTGATATCGTTTTTTCCCTTTTGGGAATTCTTCTGCTTTCTCCCGTTTTTCTTCTTCTTTATATAGC
CATTTGTCTCGAAAGTAAAGGAGGTGGTTTCTATAAACAGCTCCGTGTGGGAAGGTACGGAGGGGATTTTTATGTTTATA
AATTTCGTTCGATGCGTGTAGGGGCTGATAAAAAGGGGTTGATAACGGTAGGAGGGAGAGATCCGAGAATAACTCGTACC
GGATACCTGATCCGGAAGTATAAATTGGATGAATTGCCTCAGTTGTTTAACGTACTGAAAGGAGATATGAGTCTGGTAGG
GCCCCGTCCTGAGGTTCGTAAGTATGTGGATTTATATACCGATGAACAAAAGAAAGTATTGAGTGTACGTCCGGGGATTA
CGGATTATGCTTCTATTGAGTATGTAGATGAAAATATGATTCTTGGAGAGGCTTCGGATCCTGACAGAGCATATATAGAA
CAGATTATGCCCGATAAGATACGGTATAATATGAAATATATCTGTAATCGTTCGGTGAAGGAATATTTTAAAATTATATT
TCTGACATTTTGGAGCATCATTCGTTAG

Protein sequence : 
MIRFFDIVFSLLGILLLSPVFLLLYIAICLESKGGGFYKQLRVGRYGGDFYVYKFRSMRVGADKKGLITVGGRDPRITRT
GYLIRKYKLDELPQLFNVLKGDMSLVGPRPEVRKYVDLYTDEQKKVLSVRPGITDYASIEYVDENMILGEASDPDRAYIE
QIMPDKIRYNMKYICNRSVKEYFKIIFLTFWSIIR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1N AAL26667.1 type 8 capsule synthesis gene Virulence SCCcap1 Protein 3e-16 46
SSP0070 YP_300160.1 capsular polysaccharide synthesis protein Not tested SCC15305cap Protein 6e-17 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
wcfS YP_211035.1 undecaprenyl-phosphate galactose phosphotransferase VFG0032 Protein 1e-32 54
wcfS YP_211035.1 undecaprenyl-phosphate galactose phosphotransferase VFG1309 Protein 1e-19 42