Gene Information

Name : wcfF (BF1020)
Accession : YP_210707.1
Strain : Bacteroides fragilis NCTC 9343
Genome accession: NC_003228
Putative virulence/resistance : Virulence
Product : UDP-glucose-6 dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 1270195 - 1271472 bp
Length : 1278 bp
Strand : +
Note : Similar to previously sequenced Bacteroides fragilis UDP-glucose-6 dehydrogenase WcfF SWALL:Q9XDJ7 (EMBL:AF048749) (425 aa) fasta scores: E(): 4.5e-161, 100% id in 425 aa, and to Escherichia coli udp-glucose-6-dehydrogenase wbqA SWALL:AAO39690 (EMBL:AY208

DNA sequence :
ATGGAAGAATTAAAGATTGCCGTAATAGGTCTTGGTTATGTTGGGCTACCTTTGGCTCGATTGTTTTCGACAAAATATGA
ATGTATTGGTTTTGATCTGAACCAGTCTCGTGTTGATGCTTTAAATTCCGGTCATGATATGACTTTAGAGGTTTCTGATG
ACTTACTTCGGAAAGCGTTAGAAAATGGTTTCAAATGTACCAGTAATATTGACGAAATAAGTAATTGTAACTTTTATGTT
GTAGCTGTACCAACCCCTGTGGATTTGAATAATCGCCCCGATCTTACACCTTTGATTGGTGCGAGTACAACAGTCGGAAA
AGTTATTTCAAAAGGGGATATTGTTGTGTATGAATCTACTGTATATCCGGGAGTAACAGAGGAAGAATGTCTTCCGGTAG
TCGAAGAGGTGTCTGGGTTAACATACAATGTAGATTTTTATGCAGGTTATTCACCAGAACGTATAAACCCGGGTGATAAA
GAGCATACTGTTGAAAAGATTAAGAAAGTAACTTCCGGTTCGACTCCTGAGATTGCTGACATTGTTGATTCTGTTTATAA
TTCAGTGTTGGTTAACGGTACTCATAAAGCCCCTTCTATCAAAGTGGCTGAAGCTTCCAAAATAATAGAGAACTCCCAGC
GCGATGTGAATATTGCCTTCATGAATGAACTCTCAAAGATCTTCAATGCAATGGGCATTGATACCAATGATGTTATTGAG
GCTGCATCTTCCAAATGGAATTTTATCAAGTTGAAACCTGGCTTGGTCGGTGGTCACTGTATTAGTGTTGATCCTTATTA
TCTTATTCAGAAGGCCCAGGTTTATGGGGTACTCCCACGAATCATGTCTGCAGCAAGGCGCTTGAATGATGGTATGGGAG
ACTATGTCGCTAATCAGGTGATTAGATTAATGAATAAAAAAGGTATTCTTGTCAAAGATTCAAAGATTCTGCTTCTGGGT
TTTACTTTTAAAGAAGATTGCCCTGATATTCGAAATACCAAGGTGATAGACATTTATTCTACCTTACATGAGTATACTTC
TGACATTACCGTTTATGATGCTTGGGCTAATTCGGCTAAAGTGGCACATGAATATGGTATATCGATCCTGACTGCTGGTC
TTGATAATTTGGTTGGACAATTTGATGCGGTGGTGTTGTGTGTTGGACATAAAGAGTTCCGGCATATGAATATTCGCGGC
TTTCTCCGTTCTGATATGGGTGTTGTTTATGATGTTAAAGCTGTATTGAGTAAAGATATAATAGATGGCAGATTATAA

Protein sequence :
MEELKIAVIGLGYVGLPLARLFSTKYECIGFDLNQSRVDALNSGHDMTLEVSDDLLRKALENGFKCTSNIDEISNCNFYV
VAVPTPVDLNNRPDLTPLIGASTTVGKVISKGDIVVYESTVYPGVTEEECLPVVEEVSGLTYNVDFYAGYSPERINPGDK
EHTVEKIKKVTSGSTPEIADIVDSVYNSVLVNGTHKAPSIKVAEASKIIENSQRDVNIAFMNELSKIFNAMGIDTNDVIE
AASSKWNFIKLKPGLVGGHCISVDPYYLIQKAQVYGVLPRIMSAARRLNDGMGDYVANQVIRLMNKKGILVKDSKILLLG
FTFKEDCPDIRNTKVIDIYSTLHEYTSDITVYDAWANSAKVAHEYGISILTAGLDNLVGQFDAVVLCVGHKEFRHMNIRG
FLRSDMGVVYDVKAVLSKDIIDGRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 4e-110 54
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 4e-110 54
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-97 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
wcfF YP_210707.1 UDP-glucose-6 dehydrogenase VFG0431 Protein 2e-110 54