Gene Information

Name : thyA (lin1988)
Accession : NP_471322.1
Strain : Listeria innocua Clip11262
Genome accession: NC_003212
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 2002324 - 2003268 bp
Length : 945 bp
Strand : -
Note : similar to thymidylate synthase; ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-deriv

DNA sequence :
ATGAAACAATATTTGGATTTAGAAAAGTACGTTTTAGAGAATGGAACACAAAAAGGAGATCGCACTGGGACTGGAACAAT
CAGCACATTTGGTTATCAAATGCGTTTTGATTTACAGGAAGGCTTTCCAATTATGACAACAAAACGGGTACCATTTAAAC
TTGTAGTAAGTGAACTACTATGGTTTTTACATGGAGATACGAATATTCGCTACCTTTTACAGCATAATAATAATATTTGG
AATGAATGGGCTTTTGAGCGTTTTGTGAAAAGCGCTGATTATAAAGGCGAAGATATGACTGACTTTGGGCTGCGTGCTGA
GCGTGATCCGGCCTTTAAAGAAGTGTATCAAGCTGAAATGGAGAAGTTTAAAACGCGGATCTTAGAAGACGAAACGTTCG
CGAATAAATACGGCGAATTAGGTAATATTTACGGCAAACAATGGCGTGAATGGAAAACTTCGCAAGGGGAAACAATTGAT
CAGTTAGCTGACTTAATTGAAATGATTAAAACAAACCCGAACTCGCGTCGTTTAATCGTGTCTGCTTGGAATCCTGAAGA
TATTCCGAATATGGCTTTACCACCTTGTCATTCATTGTTTCAATTTTATGTGGCAGATGGGAAATTATCGTGCCAATTGT
ACCAACGAAGTGCAGATATTTTCTTAGGAGTACCGTTTAACATTGCAAGTTATGCACTTTTGACACATTTAATTGCACGG
GAAGTTGGACTTGATGTTGGTGAATTTATCCATACTATGGGAGATGCACATCTTTATAACAATCATATCGAACAAGTGAA
AGAACAATTATCAAGAACTCCGCATGCGTTACCAAAATTAGTTCTTTCAGATAAACCTGCAACCATTTTTGATTTTGAAG
TAGCGGATATTTCACTAGATGGTTATAATCCAGATCCTGCAATTAAAGCACCAATTTCAGTATAA

Protein sequence :
MKQYLDLEKYVLENGTQKGDRTGTGTISTFGYQMRFDLQEGFPIMTTKRVPFKLVVSELLWFLHGDTNIRYLLQHNNNIW
NEWAFERFVKSADYKGEDMTDFGLRAERDPAFKEVYQAEMEKFKTRILEDETFANKYGELGNIYGKQWREWKTSQGETID
QLADLIEMIKTNPNSRRLIVSAWNPEDIPNMALPPCHSLFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAR
EVGLDVGEFIHTMGDAHLYNNHIEQVKEQLSRTPHALPKLVLSDKPATIFDFEVADISLDGYNPDPAIKAPISV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 3e-101 64