Gene Information

Name : leuS (lin1769)
Accession : NP_471105.1
Strain : Listeria innocua Clip11262
Genome accession: NC_003212
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1764667 - 1767078 bp
Length : 2412 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGACATTTAATCATAAAAAAATGGAACCGAAATGGCAACAATATTGGAGTGAACATAACACTTTCAAAACAACAGAAGA
TAAAGATAAAGAAAACTTCTATGCACTTGATATGTTTCCTTACCCATCTGGAGCAGGTCTTCACGTAGGACATCCAGAAG
GCTATACTGCAACAGATATTTTGTCTAGAATGAAACGCATGCAAGGGAAGAACGTCCTTCATCCAATCGGTTGGGATGCA
TTTGGACTTCCTGCAGAGCAATATGCGATTGATACTGGTAACGATCCAGAAGAATTCACCGCACTGAATATTGCCAACTT
TACTCGCCAAATTAAATCTCTGGGTTTTTCCTACGATTGGGATCGTGAAATTAATACAACAGATCCTGAATATTATAAAT
GGACACAGTGGATTTTTGAAAAATTATATGAAAATGGCTTAGCTTATGAAGCCGAAATCGCTGTAAACTGGTGTCCGGCA
CTTGGAACCGTACTAGCCAATGAAGAAGTAATCGATGGCAAAAGTGAACGCGGTGGCTTCCCAGTTTTCCGTAAACCAAT
GCGTCAATGGATGCTTAAAATTACTGCCTATGCAGATCGTTTGCTAGATGACCTTGAACTTGTAGACTGGCCTGAAAATA
TTAAAGATATGCAACGTAACTGGATTGGTCGTTCAGAAGGCGCAGAAGTTACTTTTAAAATTAAAGATAGCGATGAAACG
TTTAATGTCTTTACAACACGCCCAGATACACTTTTTGGCGCAACATATACAGTTTTTGCACCAGAACACGAACTTATCGA
AAAAATCACAACACCGGAGCAAAAAGAAGCAGTTGAAGCTTATAAAAAACAAGTAGAACTAAAAAGCGAACTAGAAAGAA
CCGACCTTGCAAAAGACAAAACAGGCGTATTCACAGGAGCATATGCGATTAATCCAATCAACGGTGAAGAAGTGCCAATT
TGGATTGCGGACTACGTGTTGATTCAATATGGAACAGGTGCAATTATGGCCGTACCAGCCCACGATGAACGCGACTTTGA
ATTTGCGCAACAATTTGGTTTGAATATTCGTCCTGTTCTTGAAGGCGGCGACGTGACAAAAGAAGCATTCACTGGCGATG
GACCACATATTAACTCTGATTTCTTGAACGGACTAGCTAAAGCCGAAGCGATTACCGCTGCAATTGATTGGCTAGAAAAA
GAAGGCATCGGTAGCCGTAAAATCACGTATCGTTTGCGCGACTGGTTGTTCAGCAGACAGCGTTACTGGGGTGAACCAAT
TCCAGTTATTCACTGGGAAGACGGGGAAACAACGCTTGTACCAGAAGACGAACTACCACTACTTCTGCCAAAAGCAACAG
AAATCAAACCATCAGGAACAGGCGAATCACCACTTGCCAACTTGCATGACTGGGTAAACGTAACAGACGAAAACGGTCGA
AAAGGTCGTCGCGAAACAAATACGATGCCACAATGGGCTGGATCAAGCTGGTATTTCTTGCGCTATATCGATCCAAAAAA
CAGCGAAGCAATTGCTGATAAAGAAAAATTAGCAGAATGGCTTCCTGTAGATGTTTATATCGGCGGGGCAGAACATGCAG
TGCTTCACCTTCTTTATGCACGTTTCTGGCATAAATTCTTGTATGATATCGGCGTAGTTCCAACAAAAGAACCTTTCCAA
AAACTATTTAACCAAGGCATGATTCTTGGCGAAAATAACGAAAAAATGTCCAAATCAAGAGGCAATGTCGTTAACCCTGA
TGAAGTAGTAGAAAAATACGGTGCAGACACACTTCGCTTGTACGAAATGTTCATGGGACCACTGGAAGCTTCTATTGCTT
GGAATGAAAATGGACTAGAAGGTGCGCGTAAATTCTTAGACCGTATTTGGCGCTTGCTAGTAACTGAAGAAGGCACTCTT
GCTGAAAAAGTTACAACCGATGCGAATGCTAATTTAGAAAAAGCGTATCATCATATGGTGAAAACAGTTACTAATCATTA
CGAAAATCTGCGTTTCAATACCGGGATTTCGCAACTAATGATTTTCATCAATGAAGCATACAAACGAGATACGATTCCAA
AACAATATGTTGAAGGTTTCGTTCAACTCTTGTCCCCAATTGCACCACACCTTGCAGAAGAATTGTGGGAAATCCTTGGT
CATACAGAAACAATTAGCTATGTAGCTTGGCCAACATACGATGAAACAAAACTAGTAGAAGATGAAGTAGAAATCGTACT
TCAAGTAAATGGCAAAGTAAAAAGTAAAATCACCGTTGCAAAGTCACTCGGAAAAGAAGAACTAGAGAAACTCGCACATG
AAGACGATAAAATCAAAGAAAACATAGACGGAAAAACCATCCGTAAAGTAATCGTCGTTCCAGGAAAACTTGTAAATATT
GTTGCGAATTGA

Protein sequence :
MTFNHKKMEPKWQQYWSEHNTFKTTEDKDKENFYALDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGKNVLHPIGWDA
FGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDREINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPA
LGTVLANEEVIDGKSERGGFPVFRKPMRQWMLKITAYADRLLDDLELVDWPENIKDMQRNWIGRSEGAEVTFKIKDSDET
FNVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKTGVFTGAYAINPINGEEVPI
WIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLEGGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEK
EGIGSRKITYRLRDWLFSRQRYWGEPIPVIHWEDGETTLVPEDELPLLLPKATEIKPSGTGESPLANLHDWVNVTDENGR
KGRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQ
KLFNQGMILGENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDRIWRLLVTEEGTL
AEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYKRDTIPKQYVEGFVQLLSPIAPHLAEELWEILG
HTETISYVAWPTYDETKLVEDEVEIVLQVNGKVKSKITVAKSLGKEELEKLAHEDDKIKENIDGKTIRKVIVVPGKLVNI
VAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 68