Gene Information

Name : lin1605 (lin1605)
Accession : NP_470941.1
Strain : Listeria innocua Clip11262
Genome accession: NC_003212
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1612641 - 1614398 bp
Length : 1758 bp
Strand : -
Note : highly similar to pyruvate kinases; catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAAAAAAACGAAAATTGTTTGTACAATTGGTCCTGCAAGTGAGTCAGTTGACACATTAGTTCAGTTGATCGAAGCAGG
AATGAACGTTGCACGTCTTAATTTCTCTCACGGAGATTTTGAAGAGCACGGTGCGCGTATTGTAAATATCCGTGAAGCAT
CGAAAAAAACTGGCAAACAAGTTGCTATCTTACTTGATACAAAAGGTCCAGAAATCCGTACAAACGACATGGTCGGCGGA
AAATTAGAATTCCAAACAGGTGACGTTGTACGTGTATCTATGACTCCTGTTGAAGGAACAAAAGAAAAATTCTCTGTAAC
TTACGGAGAACTTTATGATGACGTAGAAATTGGTTCTTCCATTTTACTTGATGACGGTTTAATCGGTCTTGAAGTAATCG
AAAAAGACGAAGCTAATCGCGAACTAGTAACTAAAGTACTTAACCCAGGTGTACTTAAAAATAAAAAAGGTGTTAACGTA
CCGAATGTTTCTATCAACCTACCAGGAATCACAGAAAAAGATGCTGCTGATATCCGCTTCGGTTTAGAACAAGGTATTGA
CTTTATCGCTGCATCTTTCGTACGTCGTGCTACAGATGTTCTTGAAATTACTAAAATTTTAGAAGAGCATAACGCAACTC
ACGTACAAATCATTCCTAAAATCGAAAACCAAGAAGGCGTTGACAACATCGACGAAATCTTACAAGTATCTCAAGGCTTA
ATGGTTGCTCGTGGTGACCTAGGTGTTGAAATTCCAGCTGAAGAAGTTCCGATTGTACAAAAAGAACTTATCAGAAAATG
TAATAAACTTGGTAAACCTGTTATTACTGCTACACAAATGCTTGATTCCATGCAACGTAACCCACGTCCAACTCGCGCTG
AAGCAAGTGACGTAGCGAATGCGATTTTTGATGGAACAGATGCTATTATGTTATCCGGTGAAACAGCTGCTGGGGATTAT
CCAGTAGAAGCAGTTAAAATGATGGCGAAAATCGCTGTTCGTACTGAGGAAGTTCTAGTTGCTCAAGATAAATTTGCACT
TAAACTTCATGAAAATACAGATATGACAGAAGCTATCGGTCAAGCAGTTGGCCATACTGCGAAAAACCTAAATGTACAAA
CTATCGTTGCTGCGACTCAAAGTGGTCACACAGCTCGTATGATTTCTAAATACCGTCCAAAATCTCATATCGTTGCTGTA
ACATTCAACGAACATGTATATCGCGGATTAGCTCTTTCTTGGGGCGTATATCCTCGTCTAGCTACTCCAGTTAGCAATAC
AGACGAAATGTTTGACCTTGCAGTAAAAGAATCTCTTGCTTCAGGTGTTGCGAAACAAGGCGACCTAATCATCATCACTG
CTGGTGTTCCAGTTACAGAAAGCGGAACAACAAACGTTATGAAAATCCAATTAATTGGTGAAAAAGTAGTTAAAGGCCAA
GGTATTGGTAGCAAATCAGTTATTGGTAAAGCAGTAGTTGCTAAATCCAATGCAGAAGCTCTTCAAAAAGCAGAAGAAGG
CGGAATCTTAATCGTTAAAACAACTGATAAAGAAATCCTTCCTGCATTCGAGAAAAGTGCTGCAGTTGTTGTGGAAGAAG
GCGGCTTAACTAGCCATGCAGCAGTTGTTGGAATCAACCTTGGCATTCCTGTCATCGTTGGCGCTAAAGACGCAACATCC
CTTGTAAAAGACGGTGAAATCATCACTGTTGATTCTCGTCAAGGTGTTGTATATAACGGCAAAACAGCAACTCACTAA

Protein sequence :
MKKTKIVCTIGPASESVDTLVQLIEAGMNVARLNFSHGDFEEHGARIVNIREASKKTGKQVAILLDTKGPEIRTNDMVGG
KLEFQTGDVVRVSMTPVEGTKEKFSVTYGELYDDVEIGSSILLDDGLIGLEVIEKDEANRELVTKVLNPGVLKNKKGVNV
PNVSINLPGITEKDAADIRFGLEQGIDFIAASFVRRATDVLEITKILEEHNATHVQIIPKIENQEGVDNIDEILQVSQGL
MVARGDLGVEIPAEEVPIVQKELIRKCNKLGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGDY
PVEAVKMMAKIAVRTEEVLVAQDKFALKLHENTDMTEAIGQAVGHTAKNLNVQTIVAATQSGHTARMISKYRPKSHIVAV
TFNEHVYRGLALSWGVYPRLATPVSNTDEMFDLAVKESLASGVAKQGDLIIITAGVPVTESGTTNVMKIQLIGEKVVKGQ
GIGSKSVIGKAVVAKSNAEALQKAEEGGILIVKTTDKEILPAFEKSAAVVVEEGGLTSHAAVVGINLGIPVIVGAKDATS
LVKDGEIITVDSRQGVVYNGKTATH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-106 51
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-106 51
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-106 51
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-106 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lin1605 NP_470941.1 pyruvate kinase VFG0479 Protein 1e-106 51