Gene Information

Name : hemC (lin1591)
Accession : NP_470927.1
Strain : Listeria innocua Clip11262
Genome accession: NC_003212
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1596640 - 1597569 bp
Length : 930 bp
Strand : -
Note : highly similar to porphobilinogen deaminases (hydroxymethylbilane synthase); transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAAACGGAAAATAATTGTTGGTTCAAGACGTAGTAAATTAGCTTTAACACAGTCTAACTGGGTGATAAAAAAACTCAA
AGAAAACTATCCTGAAATCGATTTTGAAATAAAAGAAATTGTTACAAAGGGCGACCGTATTTTAGATGTTACTTTGAGTA
AAGTCGGTGGAAAAGGTCTATTTGTTTCTGAAGTTGAGCAAGCTTTGAGCGATGAAGTAATAGATTTCGCGGTACATAGT
ATGAAAGATGTGCCTTCAAGTTTGAAAGATGGACTAGTCATTGGAGCAATTCCAAAACGTGAATCCCCATTAGATTGTTT
TGTTTTTAATGAGGTAAGCACGCTAGATGACTTACCAAAAGGTGCAGTAATCGGCACAAGTAGTCTACGTCGCGCGGCAC
AACTCTTAAAACATCGTCCTGATTTTGTCGTTAAGCCAATTCGTGGCAATATTGATACTCGGCTTCAAAAATTACATGCT
GAAAACTTTGATGCAATCATTTTAGCAAAAGCTGGACTTGCACGAATGGGTTGGCTTGAAAATACGAGTTTAAAACTAGA
AGATATATCTCCTGAATTATGTTTACCTGCTGTAGGGCAAGGGGCTCTTGCTATCGAATGTAGAGAAACCGATCTTCAAA
TTTGCGATATGCTAGCTTCTATTCACCATGAAGAAACGGGAATCTGTGTAGAAGCAGAGCGCGTTTTCTTGAAAAAACTA
AATGGCGGCTGCGAAATCCCAATTGCTGGATTTGCGACAAAAACAGGCGATTCAGTTCACTTTAAAGGTTTGGTTGGTAA
CGCAGATGGTTCCATTATTCTTGAATCTGAACGAACTGGTGCGAGCCCAGCTGAAATTGGCAATCAAGTAGCTGAAGAAT
TGCTGAGTGAAGGTGCAGATACCATTATCAAAGAGCTGAGAAATATATGA

Protein sequence :
MKRKIIVGSRRSKLALTQSNWVIKKLKENYPEIDFEIKEIVTKGDRILDVTLSKVGGKGLFVSEVEQALSDEVIDFAVHS
MKDVPSSLKDGLVIGAIPKRESPLDCFVFNEVSTLDDLPKGAVIGTSSLRRAAQLLKHRPDFVVKPIRGNIDTRLQKLHA
ENFDAIILAKAGLARMGWLENTSLKLEDISPELCLPAVGQGALAIECRETDLQICDMLASIHHEETGICVEAERVFLKKL
NGGCEIPIAGFATKTGDSVHFKGLVGNADGSIILESERTGASPAEIGNQVAEELLSEGADTIIKELRNI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 9e-62 47
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 9e-62 47