Gene Information

Name : fliI (lmo0716)
Accession : NP_464243.1
Strain : Listeria monocytogenes EGD-e
Genome accession: NC_003210
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 747219 - 748520 bp
Length : 1302 bp
Strand : +
Note : similar to H+-transporting ATP synthase alpha chain FliI, flagellar-specific, -; involved in type III protein export during flagellum assembly

DNA sequence :
GTGAGCTGGTCGCCAAAAACCGAAGCTTGGCAAGAATTAAAAAACACCGTCCCATACATCCAAAAAGGGAAAATCCACAC
AGTCCAAGAACAAGTCTATATTTCTAAAGGCCCTCAAGTGAAAATTGGTGACACTGTCATGGTCGGTGAAAACAAAGTAC
TCTGCGAAGTAATCTCCATCGAAAAAGAAAATAATATGCTGCTCCCGTTTAATCAAAGCGACAAAGTGGCATACGGTGAT
TGGGTGTACGTAACGGATACGAAAATCACGATTCCGGCCGACGAATTCCTCCTCGGAAAAGTACTCAACGCATCCGGCGA
CATTTTAAACGAAGAAGCTGGTATGGCTAAATTCAAACAAAAAATGCCACTTGAAGCTCCACCAATTCATGCTTTTAGCA
GAGCAGAAATCACTGATACGCTCGAAACAGGCATCAAAGCAATTGACGGGATGTTAACGATTGGAATCGGTCAAAAAATT
GGTATTTTCGCCGGATCGGGTGTTGGGAAATCTACTTTACTTGGAATGATTGCTCGTAACGCCAAAGCAGACATTAATGT
GATTGGTTTAGTCGGCGAGCGTGGCCGTGAAGTAAAAGATTTCTTGCGTAAGGATCTTGGAGAAGACGGACTGCGCAAAA
GCGTGATTGTTGCTGCTACCTCGGACGAAAGCCATCTTATGCAACTACGCGCCGCCAAACTAGCCACTTCTATTGCCGAG
CATTTCCGCGACCAAGGAAAAACCGTCCTTCTAATGATGGATTCTGTCACTCGTTTTGCTGATGCAAGAAGAAGCGTCGA
TATCGCCGTCAAAGACTTACCAATCGGTGGAAAAACTTTGCTAATGGAATCTTATATGAAGAAATTGCTAGAACGTTCAG
GTAAAACACAAAACGGCTCGATTACTGGTATTTATACTGTGCTTGTTGATGGAGATGATATGAATGGTCCAGTCCCCGAT
TTAGCGCGGGGGATTTTAGATGGACATATCGTTCTCACCCGTGAACTCGCCACCAAAAACCACTATCCTGCCATTGATGT
CCTTGGCTCCGTTAGTCGGGTAATGGAAGAAATCGTTCCAGAAAACCAGTGGAAAACTGCTTCGAAAATTCGCGAATGGA
TGAGTATTTATCAAGAAAATGAACTATATTTCAAACTTGGTACAATCGAACAGACGAGCGACAACGCGGCGATTTTTACA
AGTAAAGAAAAGTCCTATTTTATCCATCAATTTTTAAAGCAATTGCGGGATGAAAGTGTTACGCTCGAAGAAACGAGTAA
GTTGATGGAAACGTTAGTATAA

Protein sequence :
MSWSPKTEAWQELKNTVPYIQKGKIHTVQEQVYISKGPQVKIGDTVMVGENKVLCEVISIEKENNMLLPFNQSDKVAYGD
WVYVTDTKITIPADEFLLGKVLNASGDILNEEAGMAKFKQKMPLEAPPIHAFSRAEITDTLETGIKAIDGMLTIGIGQKI
GIFAGSGVGKSTLLGMIARNAKADINVIGLVGERGREVKDFLRKDLGEDGLRKSVIVAATSDESHLMQLRAAKLATSIAE
HFRDQGKTVLLMMDSVTRFADARRSVDIAVKDLPIGGKTLLMESYMKKLLERSGKTQNGSITGIYTVLVDGDDMNGPVPD
LARGILDGHIVLTRELATKNHYPAIDVLGSVSRVMEEIVPENQWKTASKIREWMSIYQENELYFKLGTIEQTSDNAAIFT
SKEKSYFIHQFLKQLRDESVTLEETSKLMETLV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 6e-68 46
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 6e-68 46
unnamed AAL06369.1 EscN Virulence LEE Protein 9e-67 44
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-67 43
escN CAI43874.1 EscN protein Virulence LEE Protein 4e-68 42
escN YP_003223475.1 translocator EscN Virulence LEE Protein 5e-68 42
escN CAC81862.1 EscN protein Virulence LEE II Protein 5e-68 42
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 8e-68 42
escN AAL57542.1 EscN Virulence LEE Protein 6e-68 42
escN YP_003236088.1 translocator EscN Virulence LEE Protein 5e-69 42
escN AAC38383.1 EscN Virulence LEE Protein 1e-68 42
escN AAC31513.1 L0034 Virulence LEE Protein 7e-69 42
escN NP_290268.1 hypothetical protein Virulence LEE Protein 9e-69 42
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 7e-69 42
escN AAK26715.1 EscN Virulence LEE Protein 6e-68 42
ECs4568 NP_312595.1 EscN Virulence LEE Protein 9e-69 42
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-65 42
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-64 42
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-64 41
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-64 41
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-64 41
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-64 41
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-64 41
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 8e-65 41
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-50 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI NP_464243.1 flagellum-specific ATP synthase VFG2144 Protein 2e-73 46
fliI NP_464243.1 flagellum-specific ATP synthase VFG0048 Protein 1e-70 43
fliI NP_464243.1 flagellum-specific ATP synthase VFG0812 Protein 4e-69 42
fliI NP_464243.1 flagellum-specific ATP synthase VFG0730 Protein 8e-69 42
fliI NP_464243.1 flagellum-specific ATP synthase VFG0390 Protein 3e-63 42
fliI NP_464243.1 flagellum-specific ATP synthase VFG1254 Protein 2e-70 42
fliI NP_464243.1 flagellum-specific ATP synthase VFG0192 Protein 8e-70 41