Gene Information

Name : lmo0293 (lmo0293)
Accession : NP_463824.1
Strain : Listeria monocytogenes EGD-e
Genome accession: NC_003210
Putative virulence/resistance : Unknown
Product : rRNA large subunit methyltransferase
Function : -
COG functional category : S : Function unknown
COG ID : COG1576
EC number : -
Position : 319049 - 319528 bp
Length : 480 bp
Strand : +
Note : conserved hypothetical protein, highly similar to B. subtilis YydA proteinYyd; SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA

DNA sequence :
ATGAATATCCAAATTGTAACGGTCGGGAAATTAAAAGAAAAATATTTAGTGCAAGGAATCGCCGAATATTTAAAACGGTT
GAGCGCCTACGCGAAAGTGACGATTGTTGAAGTTCCGGATGAGAAAGCTCCGGAAGTGCTTAGTGATGCGGAAATGAAAC
AAGTGAAGGATAAAGAGGGTGCGCGGATTTTAGCAAAGATTCCGGACGATGCCTATGTGATTGCGCTGGCGATTGATGGG
AAAATGAAGTCGAGTGAAGAATTTGCGGCGGATTTGGATAAGCTGGCGACTTATGGTAAGAGTAAGGTGACGTTTGTGAT
TGGTGGATCGCTGGGACTTAGTGAGGCGGTGCTGAAGCGGAGTAATGAGCGGATTTCGTTTGGACGGTTGACGTTGCCGC
ACCAGTTGATGAGGTTGGTGCTGGTGGAGCAGGTTTATCGGGCGTTTCGGATTGTTCGGGGGGAGCCTTATCATAAATAG

Protein sequence :
MNIQIVTVGKLKEKYLVQGIAEYLKRLSAYAKVTIVEVPDEKAPEVLSDAEMKQVKDKEGARILAKIPDDAYVIALAIDG
KMKSSEEFAADLDKLATYGKSKVTFVIGGSLGLSEAVLKRSNERISFGRLTLPHQLMRLVLVEQVYRAFRIVRGEPYHK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
orfX YP_251938.1 rRNA large subunit methyltransferase Not tested SCCmec Protein 3e-44 63
unnamed BAC57492.1 hypothetical protein Not tested Type-IIIinv SCCmec Protein 6e-44 62
SAV0024 NP_370548.1 rRNA large subunit methyltransferase Not tested Type-II SCCmec Protein 8e-44 62
unnamed BAB72121.1 hypothetical protein Not tested Type-IVa SCCmec Protein 6e-44 62
unnamed BAB72138.1 open reading frame X Not tested Type-IVb SCCmec Protein 6e-44 62
unnamed BAC67575.1 open reading frame X Not tested Type-IVc SCCmec Protein 6e-44 62
unnamed BAA82243.1 orfX Not tested Type-II SCCmec Protein 6e-44 62
orfX AAL26648.1 unknown Not tested SCCcap1 Protein 8e-44 62
unnamed BAD24821.1 conserved hypothetical protein orfX Not tested Type-V SCCmec Protein 6e-44 62
orfX BAA86653.1 open reading frame X Not tested Type-I SCCmec Protein 6e-44 62
unnamed BAG06184.1 conserved hypothetical protein orfX Not tested Type-VII SCCmec Protein 6e-44 62
unnamed BAB47681.1 open reading frame X Not tested Type-III SCCmec Protein 6e-44 62
unnamed BAC53844.1 open reading frame X Not tested SRImec-III and SCCmec-III region Protein 6e-44 62
SAR0024 YP_039501.1 rRNA large subunit methyltransferase Not tested Type-II SCCmec Protein 8e-44 62
orfXhom BAB83497.1 open reading frame X Not tested SCC 12263 Protein 2e-39 61
unnamed ACL99851.1 hypothetical protein Not tested Type-V SCCmec Protein 4e-28 60
SE0023 NP_763578.1 rRNA large subunit methyltransferase Not tested SCCpbp4 Protein 8e-43 60
SERP2529 YP_190070.1 rRNA large subunit methyltransferase Not tested Type-II SCCmec Protein 8e-43 60
SSP0026 YP_300116.1 rRNA large subunit methyltransferase Not tested SCC15305RM Protein 5e-43 60