Gene Information

Name : serS (lmo2747)
Accession : NP_466269.1
Strain : Listeria monocytogenes EGD-e
Genome accession: NC_003210
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 2821912 - 2823195 bp
Length : 1284 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATGTTAAATTGTTACGTAATAATTTTGATGAAGTAAAGCAGAAATTACAAAATCGCGGAGAAGACCTTGGTGA
ATTCGAGAAATTTGGCGAGTTAGATAAACGCCGTCGTACATTGATTGTGGAAACAGAAGCGCTGAAAAGTCAGCGCAATG
AGGTGTCTCAAGAAATCGCTAAATTAAAACGCGAAAAACAAGACGCGGATGCTAAAATTGAAGAAATGCGTGTTGTTGGT
GATCGTATTAAAACATTAGATATCGAACTACGCGAAATTGACGAGAAGTTAGATATGATTTTAATGTCGATTCCAAATAT
TCCACACGAATCTACTCCGGTTGGCGAATCGGAAGACGATAACGTGGAAATCCGCAAATGGGGCGAAGTACGCGCATTTG
ATTTTGAACCAAAAGCGCATTGGGATTTAGGAACAGACTTAGATATCCTTGATTTTGAAAATGCTGCGAAAGTAACTGGT
AGCCGTTTTGTCTTTTATAAAAAATTAGGAGCAAGACTGGAACGAGCGCTTATTAACTTTATGATGGACTTGCATTCGAA
TGAACATGGCTACGAAGAAATGTTACCGCCTTACATGGTAAACCGTGCGAGCATGACAGGAACTGGTCAATTGCCGAAAT
TTGAAGAAGATGCTTTCTTAATTGAAGCAGAAGATTATTTCCTTATTCCAACAGCGGAAGTACCAGTAACAAACTACCAC
CGCGAAGACATTTTAAAAGCAGAAGACTTACCAAGAAAATATACAGCGTTTAGCGCATGTTTCCGCTCTGAAGCGGGATC
TGCTGGTCGCGATACGCGTGGTTTAATCCGTCAACATCAATTTAACAAAGTGGAATTAGTTCAATTTGTGAAACCGGAAG
ATTCTTACGTGGCGCTAGAAAAATTAACTGGTAACGCAGAAGAAGTATTGCGTCGCTTAGAATTGCCATACCGCGTACTA
AGCATGTGTACGGCTGATTTAGGCTTCACTGCTGCTAAAAAATATGATTTAGAAGTTTGGATTCCAAGCTACAATTCTTA
TCGTGAGATTTCTTCTTGCAGTAATTTTGAAAGCTTCCAAGCAAGACGCGCTAACATTCGTTTCCGTCGTGAACCAGGAA
GCAAGCCAGAATACGTTCATACACTTAATGGTTCCGGCTTAGCGCTAGGACGTACAGTGGCTGCCATTTTAGAAAATTAC
CAAGATGCAGATGGTTCTGTACGCATTCCAAAAGTATTGCAAGGTTACATGGGCGGTATCGAGAAAATAGAATTACCAAA
ATAA

Protein sequence :
MLDVKLLRNNFDEVKQKLQNRGEDLGEFEKFGELDKRRRTLIVETEALKSQRNEVSQEIAKLKREKQDADAKIEEMRVVG
DRIKTLDIELREIDEKLDMILMSIPNIPHESTPVGESEDDNVEIRKWGEVRAFDFEPKAHWDLGTDLDILDFENAAKVTG
SRFVFYKKLGARLERALINFMMDLHSNEHGYEEMLPPYMVNRASMTGTGQLPKFEEDAFLIEAEDYFLIPTAEVPVTNYH
REDILKAEDLPRKYTAFSACFRSEAGSAGRDTRGLIRQHQFNKVELVQFVKPEDSYVALEKLTGNAEEVLRRLELPYRVL
SMCTADLGFTAAKKYDLEVWIPSYNSYREISSCSNFESFQARRANIRFRREPGSKPEYVHTLNGSGLALGRTVAAILENY
QDADGSVRIPKVLQGYMGGIEKIELPK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-130 62