Gene Information

Name : polA (lmo1565)
Accession : NP_465090.1
Strain : Listeria monocytogenes EGD-e
Genome accession: NC_003210
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : -
Position : 1601820 - 1604447 bp
Length : 2628 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
GTGAATAAATTAGTATTAATTGATGGAAATAGTATTGCGAATCGCGCTTTTTATGCGTTACCACTTTTAAATAACGATAA
AGGTGTTTACACAAATGCGGTGTATGGATTCGCAATGATGTTGATGAATGTACTCGAAAAAGAAAAACCCAGCCATGTGC
TCGTTGCATTTGATGCTGGAAAAACAACTTTTAGACATACAACATTTAAAGGTTATAAAGGCGGACGTCAAAAAACCCCA
AGTGAGTTATCTGAACAGTTTCCATTCATCCGAGAGCTTTTAACGGCGTATGATATCCCGCAATATGAACTGGCCAATTA
CGAGGCAGACGATATTATCGGAACATTGACGAAAAAAGCGGAAGCAGATGGAATGGAAGTTGCAATTATTACCGGAGACC
GCGATTTAACACAATTAGCTTCTGAAAAAACAACGGTTTATATTACTAAAAAAGGCATAGCCGATATGGAAACCAACACA
CCAGAAACACTAAAAGAAAAATACAATCTAACTCCTGAACAAATCATTGATATGAAAGGTTTAATGGGAGATTCCTCCGA
TAATATTCCTGGGATTCCAGGCGTTGGTGAAAAAACAGCCTTAAAACTCTTACATGAATTTGGCGGAACGGTGGAAAGTG
TGTTAGAGCACGCCGAGGAAATTTCCGGTAAAAAACTAAAAGAAAAAGTACTAGAAAATAAAGAATTAGCTATTTTAAGT
AAAGAGCTAGCTACAATCAATGTGGATTCACCGATTGAATGCACAGTCGAAAGCACGAAATATGACGGGTATCAAACTGA
AAAAGTTATCCCTTTATTAAAAGAAATGAATTTTACAACACTTTTGAAAAATATCGAAGGAGATACACCGGAGGAATCGA
AAGAACTAAAAGAATTGTCTTTTGAAATAGTAACGGAATTAAAAGAACAACATTTTGGTGGGAAAACCGCACTTTATGTG
GAGCTAGAAAATGATAATTACCATACAGCAAACTTCATCGGGCTGACAGTACATTCCAGCCAAGGAACGTATTTCTTTAC
AAAAGAAACAGCTGAAAGTAGTGAGGCATTCCGCAAATGGGTAGAAAGTGATCAAACAAAAGTAGTGTATGATGCGAAGA
AAACAATAGTTGCAATGAACCGCATTGGTTTGGCAATTTCTGGTATCACATTTGATATCATGTTAGCATCTTACTTGTTA
AATCCATCTGATTCAATTGATGATTTTACAAGTGTTGCAGTAAGACATGATTACACAGAAGTAGAAACAGATGAAGCAGT
CTACGGAAAAGGTGCTAAACGTAGCACTCCTGAAGAAAGCATTGTTGCGGCACACTTAGCTAGGAAAGCAGTGGCCATTG
CTGACTTAGAGAAAAGACTAGTTGATGATTTAGAGAAAAATGAACAACTAGCTTTGATGGAAGACCTAGAGCTACCACTA
ACATTTGTTTTAGCAGAAATGGAGATGCAAGGAGTCAGCGTAGATACAGATCGGCTTGAAGATATGAAAGTAGAGCTGGG
TGGAAGACTAAAAACATTAGAAGCATCCATTCATTCACTAGCTGGCGAAGAATTCAATATTAATTCACCGAAACAACTAG
GTGTAATTTTATTTGAAAAGCTGGAACTTCCCCCAGTCAAGAAAACAAAAACAGGCTATTCAACAGCTGCGGATGTACTG
GAAAGTTTGTCTGGAAAACACGCGATTATTGATGAAATTTTGTTATATCGTCAACTTGGTAAAATTCAGTCCACTTATAT
CGAAGGGCTGCTTAAAGTGACGGATAAAGAAACACATAAGGTCCATACACGTTTCAACCAAACATTAACGCAAACGGGAC
GTTTAAGTTCAGTCGATCCGAACTTACAAAATATCCCGATTCGTTTAGAAGAAGGTCGGAAAATCAGACAAGTTTTTGTG
CCGAGTAAACCTGGTTGGAAAATGTTTTCAGCCGATTATTCTCAAGTAGAGTTGCGAGTTTTAGCACATATTTCTGAAGA
TGAGAATTTAATTTATGCATTTAAGCACGATTACGATATCCATACGAAAACAGCCATGGACGTGTTTCATGTGGAGAAGG
AAGAAGTGGATTCACTAATGCGCCGTCAAGCTAAAGCAGTAAACTTTGGTATTGTATATGGTATTAGTGATTATGGGCTT
TCGCAAAACCTTGGTATTACGCGTAAAGAAGCAAAAGACTTTATTGATCGTTACTTTGTGAGTTATCCAGCCGTGAAAGA
ATATATGCAAGACATTGTCCGTTTTGCGAAAGAAAAAGGCTATGTAGAGACCATTTTACATCGTCGTCGTTATATTCCGG
AGATTGTTAGTCGTAATTTTAATGTTCGCGGATTTGCAGAAAGAACTGCGATGAACACACCTATTCAAGGTAGTGCCGCT
GATATTATCAAAAAAGCGATGATTCTGATGAGCGAGCGTTTAGTATCTGAAAAATTAGAAGCAAAATTATTACTTCAAGT
GCACGATGAATTAATCTTCGAAGCACCTGAAGCTGAAATAGCTAAATTAGAAGAAATTGTCCCAGATGTTATGGAAAATG
CAGTAGAGCTTTCTGTGCCGCTTAAAGTAGATAGCGCCTTTGGTGACACTTGGTACGACGCGAAATAA

Protein sequence :
MNKLVLIDGNSIANRAFYALPLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAFDAGKTTFRHTTFKGYKGGRQKTP
SELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLTKKAEADGMEVAIITGDRDLTQLASEKTTVYITKKGIADMETNT
PETLKEKYNLTPEQIIDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGKKLKEKVLENKELAILS
KELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEESKELKELSFEIVTELKEQHFGGKTALYV
ELENDNYHTANFIGLTVHSSQGTYFFTKETAESSEAFRKWVESDQTKVVYDAKKTIVAMNRIGLAISGITFDIMLASYLL
NPSDSIDDFTSVAVRHDYTEVETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEKNEQLALMEDLELPL
TFVLAEMEMQGVSVDTDRLEDMKVELGGRLKTLEASIHSLAGEEFNINSPKQLGVILFEKLELPPVKKTKTGYSTAADVL
ESLSGKHAIIDEILLYRQLGKIQSTYIEGLLKVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFV
PSKPGWKMFSADYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEKEEVDSLMRRQAKAVNFGIVYGISDYGL
SQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRRYIPEIVSRNFNVRGFAERTAMNTPIQGSAA
DIIKKAMILMSERLVSEKLEAKLLLQVHDELIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 50