Gene Information

Name : hemC (lmo1556)
Accession : NP_465081.1
Strain : Listeria monocytogenes EGD-e
Genome accession: NC_003210
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1592167 - 1593096 bp
Length : 930 bp
Strand : -
Note : highly similar to porphobilinogen deaminases (hydroxymethylbilane synthase); transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAAACGGAAAATAATTGTTGGTTCTAGACGAAGCAAGTTAGCTTTAACTCAGTCTAATTGGGTGATTAATAAGCTCAA
AGAAAATTATCCTGAATTCGATTTTGAGATAAAAGAAATTGTTACAAAAGGGGACCGTATTTTAGATGTAACACTTAGCA
AAGTAGGCGGAAAAGGTCTATTTGTATCTGAAGTGGAGCAGGCTTTAAGTGATGAAGCGATTGATTTTGCGGTACATAGT
ATGAAAGATGTTCCTTCAAGTTTGAAAGAAGGGTTAATTATTGGCGCGATTCCAAAACGTGAATCTCCATTAGATTGCTT
TGTTTTCAATCAAGTGAATTCTCTAGATGAGTTACCACAAGGCTCGGTCATTGGTACAAGTAGCCTCCGTAGAGCGGCAC
AACTTCTAAAACATCGACCTGATTTTGTGATTAAACCGATTCGAGGCAATATCGATACACGTCTTCAAAAATTACATGCA
GAAAATTTTGATGCAATTATCTTAGCAAAAGCTGGGTTAGCTCGTATGGGTTGGTTAGAAAATACTACATTAAAACTAGA
AGACATCCCACCAGAAGTATGTTTGCCAGCTGTTGGACAAGGTGCACTTGCTATCGAGTGTCGCGAAAGTGATCAACAAA
TCCGCGATATGTTAACTTCTATTCATCACGAAGAAACTGGAATTTGTGTAGAAGCAGAACGTGTTTTCTTGAAAAAATTA
AACGGTGGCTGTGAAATTCCGATTGCAGGCTTTGCTACAAGAGCTAATGAATTCGTTCAGTTTAAAGGTTTAGTTGGTAA
TGCGGATGGTTCCATCATTCTTGAATCCGAACAAGTCGGTGCAAATCCAAGTGAAATTGGAAATAAAGTAGCAGAAGATT
TGCTAAGTGAAGGTGCAGATACTATTATCAAAGAACTGAGAAATGTATGA

Protein sequence :
MKRKIIVGSRRSKLALTQSNWVINKLKENYPEFDFEIKEIVTKGDRILDVTLSKVGGKGLFVSEVEQALSDEAIDFAVHS
MKDVPSSLKEGLIIGAIPKRESPLDCFVFNQVNSLDELPQGSVIGTSSLRRAAQLLKHRPDFVIKPIRGNIDTRLQKLHA
ENFDAIILAKAGLARMGWLENTTLKLEDIPPEVCLPAVGQGALAIECRESDQQIRDMLTSIHHEETGICVEAERVFLKKL
NGGCEIPIAGFATRANEFVQFKGLVGNADGSIILESEQVGANPSEIGNKVAEDLLSEGADTIIKELRNV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-63 48
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-63 48