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Name : guaA (lmo1096) Accession : NP_464621.1 Strain : Listeria monocytogenes EGD-e Genome accession: NC_003210 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : 6.3.5.2 Position : 1129945 - 1131501 bp Length : 1557 bp Strand : + Note : highly similar to GMP synthetase; contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : TTGTTTAAAATTATGAAAGACTTTACCGAGCAAGAGAAAATTATCGTTCTAGATTTTGGTAGTCAGTACAATCAACTAAT TACGCGCCGCATTCGTGAATTCGGTGTGTACAGTGAATTACATCCGCATACTATTACAGTTGAAGAAATGAAAGCACTAA ATCCAACGGGGATTATTTTTTCAGGAGGACCTAACAGTGTGTATGACGAAGATGCCTTCCGCGCTGACGAAAGAATCTTT GACATGGGAATTCCGATTTTGGGAATTTGTTACGGCATGCAATTAATGACAACGCACTTCGGTGGCAAAGTAGAACGTGC GAAAGACCGCGAATACGGGAAAGCGGACATTCACGTTGAGAAGCCAAACCGTTTATTTGCTGGACTACCAACCGATCAAG TTGTTTGGATGAGTCACGGCGATTTAGTCGTTGAGGAGCCTGCTGGTTTTGAAGTAACAGTTACTAGTAAATCTTGCCCA ATTGCAGGTATTGCGGACGAAGAACGTTCACTTTACGGCGTGCAATTCCACCCAGAAGTACGTCACTCCGTTTATGGCAA CGAATTACTGAAGAATTTTGCATTAAATGTTTGTGGCTGTAAAGGCGACTGGACAATGGAAAACTTTAGTGAAGTAGAAA TCGCAAAAATCCAAGAAATCGTAGGCGACAAAAAAGTCTTGCTTGCCCTTTCTGGCGGTGTAGATTCCTCTGTTGTTGGC GTGTTAATTCATAAAGCAATAGGCGACCAACTAACATGTATTTTCGTTGACCACGGCCTTCTTCGTAAAGGGGAAGCTGA CCAAGTAATGGAGACATTACAAGGCGAATTCAACATGAACATCATCAAAGTAGATGCGAAAAAACGCTTCATGGACAAAC TTGCTGGCGTTTCTGACCCAGAACAAAAACGTAAAATCATCGGCAACGAATTCATTTACGTATTTGACGATGAAGCCAAC AAATTAGATGGCGTAGAATTCCTTGCACAAGGAACACTCTACACAGACATCATCGAAAGTGGTACAGCAACTGCCCAAAC AATCAAGTCTCACCACAACGTAGGCGGCTTACCAGAAGATATGCAATTTAAACTAATCGAACCATTAAATACACTTTTCA AAGATGAAGTTCGCGCACTAGGAACCGAACTTGGCATGCCTGACGCAATCGTTTGGCGCCAACCATTCCCAGGCCCAGGC TTAGGAATCCGTGTGCTTGGCGAAATTACGGAAGAGAAATTAGAGATTGTTCGTGATTCTGATTACATCTTGCGTGAAGA AATCAAAAACGCAGGTCTAGAACGCGAAATCTGGCAATACTTTACTGCTCTTCCAAATATCCGTAGCGTTGGTGTTATGG GTGATGGTAGAACGTATGACCATACTGTGGTTGTTCGTGCAGTGACGAGTATTGATGGTATGACAGCCGATTGGGCACGT ATTCCGTGGGATGTACTGGAGAAAATTTCGGTACGGATTGTGAATGAAGTGGATCATGTGAATCGTGTTGTTTATGATAT TACGAGTAAGCCACCAGCTACGGTTGAGTGGGAATAG Protein sequence : MFKIMKDFTEQEKIIVLDFGSQYNQLITRRIREFGVYSELHPHTITVEEMKALNPTGIIFSGGPNSVYDEDAFRADERIF DMGIPILGICYGMQLMTTHFGGKVERAKDREYGKADIHVEKPNRLFAGLPTDQVVWMSHGDLVVEEPAGFEVTVTSKSCP IAGIADEERSLYGVQFHPEVRHSVYGNELLKNFALNVCGCKGDWTMENFSEVEIAKIQEIVGDKKVLLALSGGVDSSVVG VLIHKAIGDQLTCIFVDHGLLRKGEADQVMETLQGEFNMNIIKVDAKKRFMDKLAGVSDPEQKRKIIGNEFIYVFDDEAN KLDGVEFLAQGTLYTDIIESGTATAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRALGTELGMPDAIVWRQPFPGPG LGIRVLGEITEEKLEIVRDSDYILREEIKNAGLEREIWQYFTALPNIRSVGVMGDGRTYDHTVVVRAVTSIDGMTADWAR IPWDVLEKISVRIVNEVDHVNRVVYDITSKPPATVEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 0.0 | 76 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 0.0 | 76 |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 0.0 | 75 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 5e-129 | 53 |
