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Name : topB Accession : NP_458624.1 Strain : Salmonella enterica CT18 Genome accession: NC_003198 Putative virulence/resistance : Unknown Product : topoisomerase B Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0550 EC number : - Position : 4418728 - 4420722 bp Length : 1995 bp Strand : + Note : Previously sequenced Salmonella typhi topoisomerase B TopB TR:Q9RHF5 (EMBL:AF000001) (664 aa) fasta scores: E(): 0, 100.0% id in 664 aa. Also similar to Escherichia coli DNA topoisomerase III TopB SW:TOP3_ECOLI (P14294) (653 aa) fasta scores: E(): 0, 40.7 DNA sequence : ATGCGTCTGGTGTTGTGTGAAAAACCTTCTCAGGGCAGAGATATTGCGAAGTTTCTTGGCGCCACTCAAAGAGGCGAAGG ATTCCTGAATGGTCCGGGAGTTACAGTCACCTGGGCTCGCGGCCATCTGCTGGAGACAGCTGAACCGGAAGTATATGGCG AACAGTATGGTAAGCCATGGCGCACCGATGTGCTTCCTTTATTACCACAGCAGTGGAAACTGGTAGTCAAAGCGGATGCA AAAGCCCAATTCGCGGTAATTAACCGTCTGCTTAAACAGGTAGATGAGGTGGTAATTGCCACGGATGCTGACCGGGAAGG TGAAGTAATCGCCCGTGAGTTGCTGGATTACTGCAAGTTTCAGGGGCGTGTATTCCGGTTGTGGATGTCAGCTCTGGATG ATGCCAGTATCCGGTCAGCGTTAGCTGATTTGTGGCCGTCTTCCCGAACTGAATCGCTTTATTATGCTGGCGTGGGCAGG AGCAGGGCTGACTGGCTGATCGGTATGAATCTGACTCGCCTGTTTACACTCCTGGGGCGTGAAGCGGGTATCGGTAACGT ACTTTCAGTTGGCCGGGTACAAACGCCAACGCTGGCGATAGTGGTAAAGCGTGATCGTGAAATTGATAACTTCGTGTCGA AACCGTACTTCGAAGTTATTGCCACGATGGCCGTGAATGGCGTGTTGTTTCCATCCAAATGGGTACCGGCTGCACAGTAT TGCGATGAAGAGAAGCGTTGTATCCAGTCGGGGGTAGCGGCACAGGTGGTTCAGTTGTGTCGGCAAACGCCAACGGCTGC GATAATCAATTGCCAGATCGAGAGGAAAAAACAATCAGCGCCGCTGGCTTTCAGCCTGAGCACACTACAACAGGCCTGCT CCCGACACTGGGGGATGCCAGCCCAGACGGTACTTGATATCGCCCAGAAGTTATATGAAACCCACAAACTGACGACCTAT CCCAGAACTGACTGTGGTTATCTGCCGTTATCGATGCGAGAAGAAATCCCACAGGTACTGTCTGCTGTGGTCGGAACTGA TCCGGCGCTACAGCCGGTGGTCGCGAGTCTGGACACTCAGTTTGTGTCACGTATCTGGAATGATAAAAAAATTACCGCTC ATCACGGTATCATTCCGACAAAACATACTGGTGATCTGAGCAAACTCAGTGATGCTGAGCGCAATGTCTATCAGCTGGTC AGGTTGCACTACCTGGCCCAGTTCCTGCCCCAGATGGAAATTGACGTGACTGAGGCCACATTTAATATTGGCGGTCAGCT TTTCCGTACCCGTGGTAACGTTTTGGTGAAACCCGGCTGGAAATCTCTGTTTGGCAAAATGTCCGAAGATGATGAGGATA ATACTGGTGAAACCACACTGCCCGCCATGCAGGCGGGCCAGGTCTGCCAGGTGCAGGGCGCTGAGCAGAAGGTACTGCAG ACAAAACCGCCTGCTCCGTACAACGATGGAACTCTTATTGCCGCGATGACCAATGCGGCGGCGTTCGTTACTGACGCCGC GCTGAAAAAGGTGCTCAAAGAGAATGCGGGGATAGGAACTGAAGCAACACGGGCCGGGATAATCGACACGCTGTTGAAGC GTGGGTTTCTGGTGCGTGAGAAAAAGACGCTTAAGTCAACACCTCTTGGACGTAACCTGGTGGATGTGTTGCCAGGAACG TTAACGAATCCCGGACTTACGGCACTGTGGGAACAGATGCTGGATGAGGTAGCTGCAGGCAGGGTGAGCCTGGATGACTT TATGGCAAAGCAAAGTCAGTGGGTCAGTCAGCTGGTCGCTCAGGGGAGATCACAGCCACTGACTATGCAGGCGCCACCTT CACCACCCTGTCCTGTATGTGGCGGCAAGACGTTGCAGCGCAATGGAAAGAGTGGCTTGTTCTGGGGCTGCCTGAAATAT CCGGAGTGCAAAGGTATCGTGAACAATGGTAACAAGGGCCCCAGAGGACGCAGACGAAAACCTTCGCCAGCCTAG Protein sequence : MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLLETAEPEVYGEQYGKPWRTDVLPLLPQQWKLVVKADA KAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYCKFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGR SRADWLIGMNLTRLFTLLGREAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAVNGVLFPSKWVPAAQY CDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRHWGMPAQTVLDIAQKLYETHKLTTY PRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVASLDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLV RLHYLAQFLPQMEIDVTEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTGETTLPAMQAGQVCQVQGAEQKVLQ TKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRGFLVREKKTLKSTPLGRNLVDVLPGT LTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWVSQLVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKY PECKGIVNNGNKGPRGRRRKPSPA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| topB | AAF14809.1 | topoisomerase B | Not tested | SPI-7 | Protein | 0.0 | 100 |
| topB | NP_458624.1 | topoisomerase B | Not tested | SPI-7 | Protein | 0.0 | 100 |
| topB | NP_807836.1 | DNA topoisomerase III | Not tested | SPI-7 | Protein | 0.0 | 100 |
| PMI2630 | YP_002152332.1 | DNA topoisomerase III | Not tested | Not named | Protein | 0.0 | 58 |
| pph56 | CAI36097.1 | Topoisomerase IA | Not tested | PPHGI-1 | Protein | 5e-169 | 52 |
| topB | AAN62194.1 | putative DNA topoisomerase III | Not tested | PAGI-2(C) | Protein | 2e-171 | 51 |
| topB | AAN62317.1 | putative DNA topoisomerase III | Not tested | PAGI-3(SG) | Protein | 1e-162 | 51 |
| topB1 | YP_005176228.1 | DNA topoisomerase III | Not tested | ICEPmu1 | Protein | 2e-158 | 50 |
