Gene Information

Name : pmrA
Accession : NP_458591.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Virulence
Product : two-component response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 4378837 - 4379505 bp
Length : 669 bp
Strand : -
Note : Similar to Salmonella typhimurium transcriptional regulatory protein PmrA or BasR SW:BASR_SALTY (P36556) (222 aa) fasta scores: E(): 0, 98.6% id in 222 aa, and to Escherichia coli transcriptional regulatory protein BasR SW:BASR_ECOLI (P30843) (222 aa) fas

DNA sequence : 
ATGAAGATACTGATTGTTGAAGACGACACGCTATTATTACAGGGGTTAATACTCGCCGCGCAAACCGAAGGCTATGCGTG
TGATGGCGTTTCGACAGCGCGTGCCGCCGAGCATAGTCTGGAGTCTGGTCATTACAGTCTGATGGTGCTGGATTTAGGGC
TGCCCGATGAGGATGGCCTGCATTTCCTGACGCGAATCCGACAGAAAAAATACACCCTGCCGGTACTCATTCTGACCGCC
CGCGATACGCTCAACGACCGCATTAGCGGGCTGGATGTCGGCGCAGATGATTATCTGGTAAAACCCTTCGCCCTGGAGGA
GCTGCACGCCCGCATCCGCGCGTTGCTGCGCCGCCATAATAACCAGGGTGAAAGTGAACTGACGGTTGGCAATCTGACGC
TCAATATAGGCCGCCATCAGGCATGGAGGGATGGACAGGAACTGACCCTGACGCCTAAGGAGTACGCGCTGCTCTCACGA
TTGATGCTCAAGGCAGGCAGTCCGGTGCACCGGGAAATTCTTTATAACGATATCTACAACTGGGATAACGAACCCTCGAC
CAACACTCTGGAAGTGCATATACATAATTTGCGCGACAAAGTCGGCAAGTCGCGCATTCGCACGGTTCGCAGGTTTGGCT
ACATGCTGGTTGCCACTGAGGAAAGCTAA

Protein sequence : 
MKILIVEDDTLLLQGLILAAQTEGYACDGVSTARAAEHSLESGHYSLMVLDLGLPDEDGLHFLTRIRQKKYTLPVLILTA
RDTLNDRISGLDVGADDYLVKPFALEELHARIRALLRRHNNQGESELTVGNLTLNIGRHQAWRDGQELTLTPKEYALLSR
LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKSRIRTVRRFGYMLVATEES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
armR AAN62112.1 putative response-regulator ArmR Not tested PAGI-2(C) Protein 8e-30 43
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 3e-22 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pmrA NP_458591.1 two-component response regulator BAC0487 Protein 1e-53 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pmrA NP_458591.1 two-component response regulator VFG0473 Protein 2e-90 99
pmrA NP_458591.1 two-component response regulator VFG0596 Protein 1e-22 41