Gene Information

Name : STY4460
Accession : NP_458560.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Virulence
Product : putative type-1 secretion protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2274
EC number : -
Position : 4344317 - 4346383 bp
Length : 2067 bp
Strand : +
Note : Similar to Pasteurella haemolytica leukotoxin secretion ATP-binding protein LktB SW:HLYB_PASHA (P16532) (708 aa) fasta scores: E(): 0, 27.0% id in 567 aa, Salmonella typhimurium LtkB homolog SPI4_R TR:O85327 (EMBL:AF060869) (598 aa) fasta scores: E(): 0,

DNA sequence :
ATGGATAAAAAACTAGAACCTTATTATTTAAGTGCGGAAACGGCATTATCTATAGTGTCTAAAAAATTCAACATAAAAAT
TGACATCAAAGAGGATGATATAAATTTAAGATTTAAAAAGTACGACAGAAATAACACTGATGACTCTATACAAATGAAGA
ATTTCTTTTTGTCGTTAGGGCTTTCTCTACAGGATATATTATTTAATAATGGTGAGGATTTACTAAATGAGCCTATGCCG
ATTTTACTATTAACACCAGAAATGAAGTGGATGGTGTGTGTGAGCGGCGGGCAAAAAATAAAGTTGGTAAACGCGCGCGG
TGAACTCTGTTATGTTGAAATTGAAGATGAATATTTAAAAGAGTTATCTGCATTTAGTATACTACCTTTAAATAAAGTTG
TTGATAGTATAAGAGTAAAAAATATCATAAAAAACTCTTTATCGATGAACAAGATTTTTTATACTAAATACTTCTTTTCA
TCTCTTTTTATGGCAATTTTTGCGTTAACTATCCCAGTATTTAGTAATCTGTTCTATGATAAGCTTGTTCCAAGCGCTTC
GGTTTCATCGTTATTTGGCGTGGCTATAATTGTTGCTGTATTTATTGTTTTTGAGTTTATCCTTCGTACTTCGAAAGATA
TTTATCAGTCTATCACAGCAAGGCAGGATGACGTCGATATTGATATCGCATTTCTTGAAGCGGTACTTTATAGTAAAAAG
AAAAATGGCAGATCCATGTCATCAGCATTTGTGCTATGGAATGAGTTTCAGAAAATTAAACCCGTTTTATTAAACTCGAT
CTTTCAACGTATAGCCGATATTCCAATATTTATTATATTTCTCATTGTTATATATGTAAATTTAGGTCTGGTCGTTATTG
TACCTGTTACCATGTTTATCGTCTCTATTATTATTTTCCTCGTTAACCACCATTATACTAATGAGTTAATGAACAAACAA
AAAGAAGGACAGAAGAACAGGAATATTTTTATCTCAGAAGTTTTCTTATCTATTAAAATGATCCATACCTTAAATAATCA
AGGTTTACTTTTTGATTGGGTCAACACATCAAATGAACAGTCGTATCTTAACCTGAAGATAAGGAAATTAAATCTTATCT
ATCAATCTATATTGGGGAGTATGTCATCTATTACCCAAATAACTATTATGGTAATAGCCTTTTTTATGGTAATCAAGGGT
GATGTTACTACTGGCGCAATTGTTTCATCTGTCATTGTCTCTGGTCGTATTTCCGGGATCATTTCGAATTTTTCTTCTAC
ATTAATCTCTATTTTATCAGCAGAAAAAACCGGTAAGGATCTGCTTTCTTTTTTTGATGAAGATCAGGCAGAAAAAACAC
CGGCATTACAGTCAATATCAAAGTGCAATGGCGATATCTCTATTCGGGGCGTGAGTTATCAGTATGATGCTCAATCTCCG
ATGATTATTAATCGACTGTCTATAGACATACCTGCGGGGCAGCGTGTCGCAGTGATAGGCGAATGCGGTGCAGGAAAAAG
CTCATTACTGGGAATGCTATCTGGCTACCTTTCGCCAACAGACGGTGCCATTTTATATGATGGATATAACTTAGGACATT
TATCGCAGAACTTTTTTTCTCAGCATTTAAGTGTGGTGACGACACATGATGTTTTATTCACCGGAACCATTGAAAGTAAT
TTCGCGTTAAAACCGCAAAACGACAGGGGACGAGTACTCAAGGCGCTTCATCTGGCGAACTGTGGTTTTATCTTGCAACA
TCCTATGGGGCTGAAGTTTCCGGTGAATTTTATGGCTAAAAACCTGTCATCCGGACAGCAGCAGCAGTTATTATTAGCAC
GTAGTCTGAGCAGTAACGCCAGCGTCTTTTTATGGGATGAACCAACATCAAATCTGGATGAGAATACCGAGAAGCAAATT
TTTGATAACTTAGATGAGTTTATTCATGGGAAAACGTTGATCATGGTGACGCATCGTCGATACCTGATAAAGTATTTTGA
CCGGGTCCTGGTAATGAAAGGTGGAAAAATAATCCGTGATTGTTCTCCGGATAAATTATTAATGTAA

Protein sequence :
MDKKLEPYYLSAETALSIVSKKFNIKIDIKEDDINLRFKKYDRNNTDDSIQMKNFFLSLGLSLQDILFNNGEDLLNEPMP
ILLLTPEMKWMVCVSGGQKIKLVNARGELCYVEIEDEYLKELSAFSILPLNKVVDSIRVKNIIKNSLSMNKIFYTKYFFS
SLFMAIFALTIPVFSNLFYDKLVPSASVSSLFGVAIIVAVFIVFEFILRTSKDIYQSITARQDDVDIDIAFLEAVLYSKK
KNGRSMSSAFVLWNEFQKIKPVLLNSIFQRIADIPIFIIFLIVIYVNLGLVVIVPVTMFIVSIIIFLVNHHYTNELMNKQ
KEGQKNRNIFISEVFLSIKMIHTLNNQGLLFDWVNTSNEQSYLNLKIRKLNLIYQSILGSMSSITQITIMVIAFFMVIKG
DVTTGAIVSSVIVSGRISGIISNFSSTLISILSAEKTGKDLLSFFDEDQAEKTPALQSISKCNGDISIRGVSYQYDAQSP
MIINRLSIDIPAGQRVAVIGECGAGKSSLLGMLSGYLSPTDGAILYDGYNLGHLSQNFFSQHLSVVTTHDVLFTGTIESN
FALKPQNDRGRVLKALHLANCGFILQHPMGLKFPVNFMAKNLSSGQQQQLLLARSLSSNASVFLWDEPTSNLDENTEKQI
FDNLDEFIHGKTLIMVTHRRYLIKYFDRVLVMKGGKIIRDCSPDKLLM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY4460 NP_458560.1 putative type-1 secretion protein Not tested SPI-4 Protein 0.0 100
SC4141 YP_219128.1 bacteriocin/lantibiotic ABC transporter Not tested SPI-4 Protein 0.0 99
spi4_R AAC26655.1 ltkB homolog Virulence SPI-4 Protein 0.0 99
siiF CAE11798.1 putative type-I secretion protein (putative inner membrane component) Virulence SPI-4 Protein 0.0 99
STM4262 NP_463127.1 ABC-type bacteriocin/lantibiotic exporter Not tested SPI-4 Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
STY4460 NP_458560.1 putative type-1 secretion protein VFG0582 Protein 0.0 99