Gene Information

Name : STY4457
Accession : NP_458557.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Virulence
Product : putative type-I secretion protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1566
EC number : -
Position : 4326304 - 4327581 bp
Length : 1278 bp
Strand : +
Note : Similar to several putative type I membrane transport proteins including: Serratia marcescens LipC , involved in the extracellular secretion of lipase, TR:Q54457 (EMBL:D49826) (443 aa) fasta scores: E(): 8.4e-10, 23.0% id in 434 aa, Erwinia chrysanthemi p

DNA sequence :
ATGAATAGAAGACAAAGCGATCATCTCATGATGATAATTATTTCTTTGACGATCTTAATTATTATCCTTACCTACTTTAT
AGAAATTAATTCAGTGGTTCATGGTCAGGGTGTTATCACTACTAAAGATAATGCTCAGTTAATATCTCTTTCTAAAGGAG
GGACGATACAAGATATTTATGTGGCCGAGGGGGATACTGTAAAAAAAGGAGAACTCCTTGCAAAGGTCGTTAACTTTGAT
CTGCAAAAAGAATATCAAAGGTATAGAACTCAAAAAGGGTATCTGGATAAAGATGTTAACGAAATATCTTTCATTCTTGA
TAAAGAAAATGAGAGTGGATTGATTACCCTGGATGGCACCCGTTCTTTAAGCAACAAAGAGGTAAAAGCGAATATTGAAT
TAGTGCATAGTCAGATAAGAGCTAAAGAGTTAAAAAAAACCTCTCTTGATTCTGAGATTAGCGGATTACAAGAGAAGCTA
AGTTCGAAAGAAAAAGAACTAGCATTGCTTGCCGAAGAAATAAATATTCTTTCTCCACTGGTAAAAAAAGGAATTAGCCC
ATATACCAATTTTCTTAACAAGAAACAGGCGTATATAAAAGTTAAGTCTGAAATTAATGATATTGAAAGTAGCATCACTT
TAAAAAAAGATGATATTGAGCTGGTTGTTAATGATATTGAGGCGCTTAATAATGAATTGCGATTATCTTTATCTAAAATA
ATATCTAAAAATCTTCAGGAACTTGAGGTTGTTAACTCTACATTAAAAGTAATAGAGAAGCAGATAAATGAGGAGGATAT
CTATTCACCGGTTGACGGTGTAATTTATAAAATCAATAAAAGTGCCACTACTCATGGTGGTGTGATTCAGGCGGCGGACT
TACTTTTTGAAATAAAACCAAAAGTAAGGACTATGCTGGCCGATGTGAAAATACTACCAAAATACCGTGACCAAATATAT
GTAGATGAAGCCGTTAAGCTAGATGTCCAGTCAATTATTCAACCAAAGATAAAATCGTATAATGCGACTATCGATAATAT
TAGCCCTGACTCTTATGAGGAAAATACCGGAGGAACAATTCAGCGTTATTATAAAGTAATTATTGCATTCGATGTTAATG
AAGATGATTTACGGTGGTTAAAACCAGGTATGACTGTTGACGCCAGTGTAATTACCGGAAAACACAGCATTATGGAATAC
CTGTTATCTCCTTTGATGAAAGGCGTGGACAAAGCCTTTTCAGAACCAGTTAATACTAAACGATTAGATACACCTTGA

Protein sequence :
MNRRQSDHLMMIIISLTILIIILTYFIEINSVVHGQGVITTKDNAQLISLSKGGTIQDIYVAEGDTVKKGELLAKVVNFD
LQKEYQRYRTQKGYLDKDVNEISFILDKENESGLITLDGTRSLSNKEVKANIELVHSQIRAKELKKTSLDSEISGLQEKL
SSKEKELALLAEEINILSPLVKKGISPYTNFLNKKQAYIKVKSEINDIESSITLKKDDIELVVNDIEALNNELRLSLSKI
ISKNLQELEVVNSTLKVIEKQINEEDIYSPVDGVIYKINKSATTHGGVIQAADLLFEIKPKVRTMLADVKILPKYRDQIY
VDEAVKLDVQSIIQPKIKSYNATIDNISPDSYEENTGGTIQRYYKVIIAFDVNEDDLRWLKPGMTVDASVITGKHSIMEY
LLSPLMKGVDKAFSEPVNTKRLDTP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY4457 NP_458557.1 putative type-I secretion protein Not tested SPI-4 Protein 1e-175 100
SC4139 YP_219126.1 membrane permease, cation efflux pump Not tested SPI-4 Protein 8e-175 99
STM4260 NP_463125.1 cation efflux pump Not tested SPI-4 Protein 8e-175 99
spi4_D AAC26642.1 HLYD family secretion protein Virulence SPI-4 Protein 6e-175 99
siiD CAE11796.1 putative type-I secretion protein, putative inner membrane component Virulence SPI-4 Protein 6e-175 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
STY4457 NP_458557.1 putative type-I secretion protein VFG0580 Protein 3e-175 99