Gene Information

Name : STY4116
Accession : NP_458246.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase B
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.22
Position : 3978586 - 3980124 bp
Length : 1539 bp
Strand : +
Note : Fasta hit to ALDA_ECOLI (478 aa), 33% identity in 478 aa overlap; Fasta hit to FEAB_ECOLI (499 aa), 34% identity in 481 aa overlap; Fasta hit to YNEI_ECOLI (462 aa), 31% identity in 465 aa overlap; Fasta hit to DHAB_ECOLI (489 aa), 38% identity in 478 aa

DNA sequence :
ATGACGAACAATCCCCCTTCAACACGTATTCAGCCAAGTGAATACGGGTACCCACTGAAGTTAAAAGCCCGCTATGACAA
TTTTATTGGCGGTGACTGGGTTGCGCCCGCCGACGGCGAATATTATCAAAACCTGACGCCAGTGACCGGCCAGCCGCTAT
GTGAAGTCGCTTCCTCCGGTAAAAAAGATATCGATTTAGCGCTCGACGCCGCGCATAAGGCGAAAGATAAGTGGGCGCAT
ACGTCAGTACAAGACCGTGCCGCTATCTTGTTTAAGATCGCCGATCGGATGGAACAAAACCTCGAACTGTTGGCGACAGC
GGAAACTTGGGATAACGGTAAACCGATTCGTGAAACCAGTGCCGCCGACATACCGCTGGCGATCGATCATTTCCGCTATT
TCGCCTCCTGTATACGTGCGCAGGAGGGCGGGATCAGCGAAGTTGATAGCGAAACCGTGGCCTACCATTTTCACGAACCG
CTTGGTGTCGTGGGGCAGATAATCCCGTGGAACTTTCCGCTGCTGATGGCAAGCTGGAAAATGGCGCCAGCGCTGGCGGC
AGGTAACTGCGTGGTGCTTAAACCGGCACGCCTGACGCCGCTTTCCGTTTTACTGTTAATGGAAGTCATTGGCGATCTGT
TACCGCCGGGCGTTGTCAACGTCGTGAACGGCGCGGGCGGCGAGATTGGCGAATATCTGGCGACCTCAAAACGTATCGCG
AAGGTGGCGTTTACCGGTTCGACGGAAGTGGGTCAACAGATCATGCAGTACGCCACGCAGAACATTATTCCGGTGACGCT
GGAGTTAGGCGGCAAGTCGCCCAATATCTTCTTCGCCGACGTGATGGATGAGGAAGATGCGTTCTTTGATAAAGCGCTGG
AGGGATTTGCCCTGTTTGCCTTTAACCAGGGCGAGGTGTGTACCTGTCCAAGCCGTGCGCTGGTTCAGGAGTCCATCTAT
GAGCGCTTTATGGAGCGCGCTATTCGCCGGGTGGAGAGCATTCGCAGCGGGAACCCGCTAGATAGCGGTACACAGATGGG
AGCGCAGGTCTCTCACGGCCAGCTTGAGACTATCCTCAATTATATCGATATCGGTAAAAAAGAGGGGGCCGATATTCTGA
CCGGTGGGCGACGCAAGGAACTGGATGGCGAACTTAAAGAGGGCTATTACCTTGAGCCTACCATTCTGTTTGGTAAGAAT
AATATGCGCGTCTTTCAGGAGGAGATCTTTGGCCCGGTGCTGGCGGTAACCACCTTTAAAACCATGGAGAAGGCGCTGGA
AATCGCTAACGATACGCAATATGGCCTGGGTGCTGGCGTCTGGAGCCGCAACGGCAATCTGGCCTATAAGATGGGGCGCG
GCATTCAGGCCGGGCGCGTATGGACCAACTGCTATCACGCCTATCCGGCACATGCGGCGTTTGGCGGCTATAAGCAGTCG
GGCATCGGGCGCGAAACCCATAAGATGATGCTGGAACACTACCAGCAAACCAAGTGCCTGTTGGTGAGTTATTCCGATAA
GCCGCTGGGGCTGTTCTGA

Protein sequence :
MTNNPPSTRIQPSEYGYPLKLKARYDNFIGGDWVAPADGEYYQNLTPVTGQPLCEVASSGKKDIDLALDAAHKAKDKWAH
TSVQDRAAILFKIADRMEQNLELLATAETWDNGKPIRETSAADIPLAIDHFRYFASCIRAQEGGISEVDSETVAYHFHEP
LGVVGQIIPWNFPLLMASWKMAPALAAGNCVVLKPARLTPLSVLLLMEVIGDLLPPGVVNVVNGAGGEIGEYLATSKRIA
KVAFTGSTEVGQQIMQYATQNIIPVTLELGGKSPNIFFADVMDEEDAFFDKALEGFALFAFNQGEVCTCPSRALVQESIY
ERFMERAIRRVESIRSGNPLDSGTQMGAQVSHGQLETILNYIDIGKKEGADILTGGRRKELDGELKEGYYLEPTILFGKN
NMRVFQEEIFGPVLAVTTFKTMEKALEIANDTQYGLGAGVWSRNGNLAYKMGRGIQAGRVWTNCYHAYPAHAAFGGYKQS
GIGRETHKMMLEHYQQTKCLLVSYSDKPLGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-140 64
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-145 63
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-145 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-145 63
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-144 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
STY4116 NP_458246.1 aldehyde dehydrogenase B VFG0082 Protein 3e-140 64