Gene Information

Name : STY3769
Accession : NP_457953.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 3634542 - 3635702 bp
Length : 1161 bp
Strand : -
Note : Fasta hit to METC_ECOLI (395 aa), 31% identity in 394 aa overlap; Orthologue of E. coli metB (METB_ECOLI); Fasta hit to METB_ECOLI (386 aa), 96% identity in 386 aa overlap

DNA sequence :
ATGACGCGTAAACAGGCCACTATCGCAGTGCGTAGCGGATTAAACGATGACGAACAATACGGCTGCGTTGTGCCGCCAAT
CCATCTCTCCAGTACCTATAACTTTACCGGTTTCAATGAGCCGCGCGCGCATGATTATTCCCGCCGCGGTAATCCCACGC
GTGATGTGGTTCAGCGCGCATTAGCGGAACTGGAAGGCGGCGCGGGCGCAGTATTGACGAATACCGGCATGTCGGCGATT
CATCTGGTCACCACCGTTTTCCTCAAGCCGGGCGATCTGCTGGTCGCGCCGCATGATTGCTACGGCGGCAGTTATCGTCT
GTTTGACAGTCTGGCGACGCGCGGCTGTTATCGTGTGCGGTTTGTCGATCAGGGCGATGAACGCGCCTTACAGGCGGCGC
TGGAAGAAAAACCGAAGCTGGTACTGGTAGAAAGTCCAAGTAATCCATTGTTACGCGTGGTGGATATTGCGAAAATCTGT
CGGCTGGCGCGCGAGGCGGGCGCAGTGAGCGTCGTTGATAACACATTTTTAAGCCCGGCGCTGCAAAATCCGCTGGCGTT
GGGTGCCGATCTGGTGTTGCATTCATGCACGAAATATCTCAATGGTCATTCGGATGTCGTGGCCGGCGTGATGATTGCTA
AGGATCCGGAAATGGTCACTGAACTGGCGTGGTGGGCGAATAATATTGGCGTGACCGGCGGGGCGTTTGATAGCTATCTG
CTGCTGCGCGGTTTGCGAACTCTGGTGCCGCGTATGGAGCTGGCGCAGCGCAACGCGCAGGCGATTGTGAAATATCTGCA
AACCCAGCCGTTGGTGAAAAAACTGTATCACCCGTCGCTGCCGAATAATCAGGGACATGAGATTGCCGCGCGTCAGCAAA
AAGGCTTTGGCGCAATGTTGAGTTTTGAACTGGATGGGGATGAGGAGACGCTACGTCGTTTTCTGGGCGGGCTGTCGCTG
TTTACGCTGGCGGAATCTTTAGGGGGAGTGGAAAGTTTGATCTCTCACGCCGCCACCATGACGCATGCCGGTATGTCGCC
GCAGGCGCGTGCCGCCGCCGGGATCTCCGAAACGCTACTGCGTATCTCCACCGGTATTGAAGATGGCGAAGATTTAATTG
CCGACCTGGAAAATGGCTTCCGGGCTGCAAACAAGGGGTAA

Protein sequence :
MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAI
HLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLATRGCYRVRFVDQGDERALQAALEEKPKLVLVESPSNPLLRVVDIAKIC
RLAREAGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVMIAKDPEMVTELAWWANNIGVTGGAFDSYL
LLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPNNQGHEIAARQQKGFGAMLSFELDGDEETLRRFLGGLSL
FTLAESLGGVESLISHAATMTHAGMSPQARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-61 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-62 43
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 8e-51 41