Gene Information

Name : spaR
Accession : NP_457282.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Virulence
Product : secretory protein (associated with virulence)
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4791
EC number : -
Position : 2884590 - 2885381 bp
Length : 792 bp
Strand : -
Note : Highly similar to Salmonella typhimurium surface presentation of antigens protein SpaR SW:SPAR_SALTY (P40701) (263 aa) fasta scores: E(): 0, 99.2% id in 263 aa and to Shigella flexneri SpaR SW:SPAR_SHIFL (P40706) (256 aa) fasta scores: E(): 0, 49.4% id in

DNA sequence :
ATGCTTTACGCGTTGTACTTTGAAATTCATCACCTGGTTGCGTCTGCGGCACTAGGGTTTGCTCGCGTAGCGCCGATTTT
TTTCTTCCTGCCGTTTTTGAATAGCGGGGTATTAAGCGGCGCGCCGAGAAACGCCATTATCATCCTGGTGGCATTGGGAG
TATGGCCGCATGCATTGAACGAGGCGCCGCCGTTTTTATCGGTGGCGATGATCCCGTTAGTTCTGCAAGAAGCGGCGGTA
GGCGTCATGCTGGGCTGTCTGCTGTCATGGCCTTTTTGGGTTATGCATGCGCTGGGTTGTATTATCGATAACCAGCGAGG
GGCAACGCTAAGTAGCAGTATCGATCCGGCAAACGGTATTGATACCTCGGAAATGGCTAATTTCCTGAATATGTTTGCCG
CTGTCGTTTATTTACAAAACGGCGGTCTGGTCACGATGGTTGACGTGTTAAATAAAAGCTATCAGCTATGCGATCCGATG
AACGAGTGCACGCCTTCATTACCGCCGCTATTAACGTTTATTAATCAGGTGGCTCAAAACGCCTTGGTTCTGGCCAGTCC
GGTGGTATTAGTGCTGTTGCTGTCAGAAGTATTCCTGGGTTTATTGTCGCGCTTTGCTCCGCAAATGAACGCTTTTGCGA
TTTCACTGACGGTAAAAAGCGGCATTGCCGTTTTAATTATGCTGCTTTATTTCTCTCCGGTACTACCGGACAATGTACCG
CGACTCTCTTTCCAGGCCACAGGGTTAAGCAGTTGGTTTTACGAGCGAGGGGCGACGCATGTCCTCGAATAA

Protein sequence :
MLYALYFEIHHLVASAALGFARVAPIFFFLPFLNSGVLSGAPRNAIIILVALGVWPHALNEAPPFLSVAMIPLVLQEAAV
GVMLGCLLSWPFWVMHALGCIIDNQRGATLSSSIDPANGIDTSEMANFLNMFAAVVYLQNGGLVTMVDVLNKSYQLCDPM
NECTPSLPPLLTFINQVAQNALVLASPVVLVLLLSEVFLGLLSRFAPQMNAFAISLTVKSGIAVLIMLLYFSPVLPDNVP
RLSFQATGLSSWFYERGATHVLE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
spaR NP_457282.1 secretory protein (associated with virulence) Virulence SPI-1 Protein 7e-106 100
spaR NP_806491.1 virulence-associated secretory protein Virulence SPI-1 Protein 7e-106 100
spaR NP_461809.1 needle complex export protein Virulence SPI-1 Protein 2e-104 99
spaR YP_217807.1 surface presentation of antigens; secretory proteins Virulence SPI-1 Protein 5e-102 98
spaR AAS66867.1 SpaR Not tested SSR-2 Protein 2e-33 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
spaR NP_457282.1 secretory protein (associated with virulence) VFG0549 Protein 9e-105 99
spaR NP_457282.1 secretory protein (associated with virulence) VFG1014 Protein 6e-36 52
spaR NP_457282.1 secretory protein (associated with virulence) VFG2453 Protein 5e-32 44
spaR NP_457282.1 secretory protein (associated with virulence) VFG1771 Protein 7e-25 41