Gene Information

Name : spaS
Accession : NP_457281.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Virulence
Product : secretory protein (associated with virulence)
Function : -
COG functional category : N : Cell motility
COG ID : COG1377
EC number : -
Position : 2883533 - 2884603 bp
Length : 1071 bp
Strand : -
Note : Similar to Salmonella typhimurium surface presentation of antigens protein SpaS SW:SPAS_SALTY (P40702) (356 aa) fasta scores: E(): 0, 99.4% id in 356 aa. Contains possible membrane spanning hydrophobic domains.

DNA sequence :
ATGTCCTCGAATAAAACAGAAAAACCGACTAAAAAACGGCTGGAAGACTCCGCTAAAAAAGGCCAGTCATTTAAAAGTAA
AGATCTCATTATCGCCTGTCTGACGCTGGGAGGAATTGCCTATCTGGTGTCGTATGGCTCATTTAATGAGTTTATGGGGA
TAATTAAGATCATTATTGCGGATAATTTTGATCAGAGCATGGCTGATTACAGTTTGGCCGTTTTTGGGATAGGATTAAAA
TATCTGATTCCATTTATGCTGCTCTGTTTAGTGTGTTCCGCATTACCGGCGTTATTACAGGCCGGTTTCGTGCTGGCGAC
AGAAGCATTAAAACCTAATTTATCGGCGTTAAACCCGGTAGAAGGGGCGAAAAAACTTTTTAGTATGCGCACGGTTAAAG
ATACGGTCAAAACCCTACTGTATCTCTCATCCTTTGTGGTGGCCGCCATCATTTGCTGGAAGAAATATAAGGTTGAAATC
TTTTCTCAGTTAAATGGCAATGTTGTGGATATTGCCGTCATTTGGCGTGAACTTCTCCTCGCATTGGTATTAACTTGCCT
TGCTTGCGCATTGATTGTCTTATTATTGGATGCTATTGCGGAATATTTCCTGACCATGAAAGATATGAAAATGGATAAGG
AAGAAGTGAAGCGTGAAATGAAGGAGCAGGAAGGGAACCCAGAGGTTAAATCTAAAAGACGTGAAGTTCATATGGAAATT
CTGTCTGAACAGGTGAAATCCGATATTGAAAACTCACGCCTGATTGTTGCCAACCCCACGCATATTACGATCGGGATTTA
TTTTAAACCCGAATTGATGCCGATTCCGATGATCTCGGTGTATGAAACGAATCAGCGCGCACTGGCCGTCCGCGCCTATG
CGGAGAAGGTTGGCGTACCTGTGATCGTCGATATCAAACTGGCGCGCAGTCTTTTCAAAACCCATCGCCGTTATGATCTG
GTGAGTCTGGAAGAAATTGATGAAGTTTTACGTCTTCTGGTTTGGCTGGAAGAGGTAGAAAACGCGGGCAAAGACGTTAT
TCAGCCACAAGAAAACGAGGTACGGCATTGA

Protein sequence :
MSSNKTEKPTKKRLEDSAKKGQSFKSKDLIIACLTLGGIAYLVSYGSFNEFMGIIKIIIADNFDQSMADYSLAVFGIGLK
YLIPFMLLCLVCSALPALLQAGFVLATEALKPNLSALNPVEGAKKLFSMRTVKDTVKTLLYLSSFVVAAIICWKKYKVEI
FSQLNGNVVDIAVIWRELLLALVLTCLACALIVLLLDAIAEYFLTMKDMKMDKEEVKREMKEQEGNPEVKSKRREVHMEI
LSEQVKSDIENSRLIVANPTHITIGIYFKPELMPIPMISVYETNQRALAVRAYAEKVGVPVIVDIKLARSLFKTHRRYDL
VSLEEIDEVLRLLVWLEEVENAGKDVIQPQENEVRH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
spaS NP_457281.1 secretory protein (associated with virulence) Virulence SPI-1 Protein 2e-133 100
spaS NP_806490.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 2e-133 100
spaS YP_217806.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 2e-132 99
spaS NP_461808.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 6e-133 99
spaS AAS66868.1 SpaS Not tested SSR-2 Protein 2e-67 55
ECs3721 NP_311748.1 surface presentation of antigens protein SpaS Not tested LIM Protein 5e-59 54
ysaU AAS66849.1 YsaU Not tested SSR-1 Protein 2e-43 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
spaS NP_457281.1 secretory protein (associated with virulence) VFG0548 Protein 2e-133 99
spaS NP_457281.1 secretory protein (associated with virulence) VFG1015 Protein 2e-51 49
spaS NP_457281.1 secretory protein (associated with virulence) VFG2452 Protein 3e-48 45