Gene Information

Name : sipB
Accession : NP_457279.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Virulence
Product : pathogenicity island 1 effector protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2881114 - 2882895 bp
Length : 1782 bp
Strand : -
Note : Previously sequenced Salmonella typhi SipB TR:Q56134 (EMBL:X82670) (593 aa) fasta scores: E(): 0, 100.0% id in 593 aa. Also highly similar to Shigella flexneri 62 kDa membrane antigen ipaB SW:IPAB_SHIFL (P18011) (580 aa) fasta scores: E(): 0, 41.5% id in

DNA sequence :
ATGGTAAATGACGCAAGTAGCATTAGCCGTAGCGGATATACCCAAAATCCGCGCCTCGCTGAGGCGGCTTTTGAAGGCGT
TCGTAAGAACACGGACTTTTTAAAAGCGGCGGATAAAGCTTTTAAAGATGTGGTGGCAACGAAAGCGGGCGACCTTAAAG
CCGGAACAAAGTCCGGCGAGAGCGCTATTAATACGGTGGGTCTAAAGCCGCCTACGGACGCCGCCCGGGAAAAACTCTCC
AGCGAAGGGCAATTGACATTACTGCTTGGCAAGTTAATGACACTACTGGGCGATGTTTCGCTGTCTCAACTGGAGTCTCG
TCTGGCGGTATGGCAGGCGATGATTGAGTCACAAAAAGAGATGGGGATTCAGGTATCGAAAGAATTCCAGACGGCTCTGG
GAGAGGCTCAGGAGGCGACGGATCTCTATGAAGCCAGCATCAAAAAGACGGATACCGCCAAGAGTGTTTATGACGCTGCG
GCCAAAAAACTGACGCAGGCGCAAAATAAATTGCAATCGCTGGACCCAGCTGACCCCGGCTATGCACAAGCTGAAGCCGC
GGTAGAACAGGCCGGAAAAGAAGCGACAGAGGCGAAAGAGGCCTTAGATAAGGCCACGGATGCGACGGTTAAAGCAGGCA
CAGACGCCAAAGCGAAAGCCGAGAAAGCGGATAACATTCTGACCAAATTCCAGGGAACGGCTAATGCCGCCTCTCAGAAT
CAGGTTTCCCAGGGTGAGCAGGATAATCTGTCAAATGTCGCCCGCCTCACTATGCTCATGGCCATGTTTATTGAGATTGT
GGGCAAAAATACGGAAGAAAGCCTGCAAAACGATCTTGCGCTTTTCAACGCCTTGCAGGAAGGGCGTCAGGCGGAGATGG
AAAAGAAATCGGCTGAATTCCAGGAAGAGACGCGCAAAGCCGAGGAAACGAACCGCATTATGGGATGTATCGGGAAAGTC
CTCGGCGCGCTGCTAACCATTGTCAGCGTTGTGGCCGCTGTTTTTACCGGTGGGGCGAGTCTGGCGCTGGCTGCGGTGGG
ACTTGCGGTAATGGTGGCCGATGAAATTGTGAAGGCGGCGACGGGGGTGTCGTTTATTCAGCAGGCGCTAAACCCGATTA
TGGAGCATGTGCTGAAGCCGTTAATGGAGCTGATTGGCAAGGCGATTACCAAAGCGCTGGAAGGATTAGGCGTCGATAAG
AAAACGGCAGAGATGGCAGGCAGCATTGTTGGTGCGATTGTCGCCGCTATTGCCATGGTAGCGGTCATTGTGGTGGTCGC
AGTTGTCGGGAAAGGCGCGGCGGCGAAACTGGGTAACGCGCTGAGCAAAATGATGGGCGAAACGATTAAGAAGTTGGTGC
CTAACGTGCTGAAACAGTTGGCACAAAACGGCAGCAAACTCTTTACCCAGGGGATGCAACGTATTACTAGCGGCCTGGGT
AATGTGGGTAGCAAGATGGGCCTGCAAACGAATGCCTTAAGTAAAGAGCTGGTAGGTAATACCCTAAATAAAGTGGCGTT
GGGCATGGAAGTCACGAATACCGCAGCCCAGTCAGCCGGTGGGGTTGCCGAGGGGGTATTTATTAAAAATGCCAGCGAGG
CGCTTGCTGATTTTATGCTCGCCCGTTTTGCCATGGATCAGATTCAGCAGTGGCTTAAACAATCCGTAGAAATATTTGGT
GAAAACCAGAAGGTAACGGCGGAACTGCAAAAAGCCATGTCTTCTGCGGTACAGCAAAATGCGGATGCTTCGCGTTTTAT
TCTGCGCCAGAGTCGCGCATAA

Protein sequence :
MVNDASSISRSGYTQNPRLAEAAFEGVRKNTDFLKAADKAFKDVVATKAGDLKAGTKSGESAINTVGLKPPTDAAREKLS
SEGQLTLLLGKLMTLLGDVSLSQLESRLAVWQAMIESQKEMGIQVSKEFQTALGEAQEATDLYEASIKKTDTAKSVYDAA
AKKLTQAQNKLQSLDPADPGYAQAEAAVEQAGKEATEAKEALDKATDATVKAGTDAKAKAEKADNILTKFQGTANAASQN
QVSQGEQDNLSNVARLTMLMAMFIEIVGKNTEESLQNDLALFNALQEGRQAEMEKKSAEFQEETRKAEETNRIMGCIGKV
LGALLTIVSVVAAVFTGGASLALAAVGLAVMVADEIVKAATGVSFIQQALNPIMEHVLKPLMELIGKAITKALEGLGVDK
KTAEMAGSIVGAIVAAIAMVAVIVVVAVVGKGAAAKLGNALSKMMGETIKKLVPNVLKQLAQNGSKLFTQGMQRITSGLG
NVGSKMGLQTNALSKELVGNTLNKVALGMEVTNTAAQSAGGVAEGVFIKNASEALADFMLARFAMDQIQQWLKQSVEIFG
ENQKVTAELQKAMSSAVQQNADASRFILRQSRA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sipB NP_457279.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 0.0 100
sipB NP_806488.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 0.0 100
sipB NP_461806.1 translocation machinery component Virulence SPI-1 Protein 0.0 99
sipB YP_217804.1 cell invasion protein Virulence SPI-1 Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sipB NP_457279.1 pathogenicity island 1 effector protein VFG0546 Protein 0.0 99
sipB NP_457279.1 pathogenicity island 1 effector protein VFG0987 Protein 5e-70 43